Results 61 to 70 of about 4,735 (197)

A Theoretical Model for the Treatment of Androgenetic Alopecia Using the STEAP3 Protein, and the Genetic Challenges of Treating AGA

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Androgenetic alopecia (AGA) is a prevalent condition. The treatment methods currently available for this condition have limited potential (minoxidil) and side effects with long‐term therapy that affect the physiology of the male population (5α‐reductase inhibitors).
Ignacy Klemens Młodzianowski, Małgorzata Grochocka, Tadeusz Tadrowski, Marta Hałas‐Wiśniewska, Magdalena Izdebska   +4 more
wiley   +1 more source

Integrating Prostate‐Specific Antigen Density and Prostate Imaging Reporting and Data System Scores to Optimize Detection of Clinically Significant Prostate Cancer: A Multivariable Risk Model Approach

Journal of Clinical Laboratory Analysis, Volume 40, Issue 12, June 2026.
For the detection of clinically significant prostate cancer, incorporating PSA density into PI‐RADS‐based assessment improved clinical net benefit compared with PI‐RADS alone. The addition of DRE and age to this combined model produced only marginal further gain, indicating that most of the incremental clinical value was derived from PSA density rather
Yunus Kayali
wiley   +1 more source

To compare the efficacy and safety of silodosin and dutasteride combination with alfuzosin and dutasteride combination in patients of benign prostatic hyperplasia: a randomized, open label study [PDF]

, 2019
Background: BPH is a major cause of bothersome lower urinary tract symptoms (LUTS) and affects quality of life (QoL) which deteriorates if not taken care with the passage of time.
Tandon, Vishal R., Gupta, Rahul, Kahkashan, Iram, Chawdhary, Shabnam   +3 more
core   +1 more source

Potential Anticancer, Anti-inflammatory, and Antioxidant Effects of Dutasteride on LNCap Prostate Cancer Cell Line

Medical Journal of Babylon
Background: Prostate cancer (PCa) is one of the main causes of death in men across the world. Particular focus has been placed on its preventative and treatment techniques, which include focusing on the activity of 5-alpha reductase enzyme which is ...
Zahraa Abdulhasan Jihad, Majid Kadhim Abbas, Kaiser N. Madlum   +2 more
doaj   +1 more source

Improvement of Overactive Bladder Symptoms and Bladder Ischemia with Dutasteride in Patients with Benign Prostatic Enlargement. [PDF]

, 2015
OBJECTIVES: To evaluate the correlation of clinical and urodynamic parameters with bladder vascular resistance before and after dutasteride treatment in patients with lower urinary tract symptoms associated with benign prostatic enlargement. METHODS: A
Hashizume, Kazumi, キタ, マサフミ, Kakizaki, Hidehiro, 松本, 成史, 橋爪, 和純, Kita, Masafumi, 柿崎, 秀宏, ワダ, ナオキ, ハシヅメ, カズミ, 北, 雅史, カキザキ, ヒデヒロ, Matsumoto, Seiji, マツモト, セイジ, 和田, 直樹, Wada, Naoki   +14 more
core   +1 more source

Comparison of oral minoxidil, finasteride, and dutasteride for treating androgenetic alopecia

, 2022
Background Androgenetic alopecia (AGA) is the most common cause of hair loss, often challenging to treat. While oral finasteride (1 mg/d) is an FDA-approved treatment for male AGA, oral minoxidil and oral dutasteride are not approved yet.
Greg Williams, Mesbah Talukder, Aditya K. Gupta   +2 more
core   +1 more source

Efficacy and safety of oral finasteride versus dutasteride in moderate-to-severe androgenetic alopecia in males based on trichoscopic and laboratory findings: a clinical comparison in Iran

Journal of Dermatological Treatment
Background Androgenetic alopecia (AGA) is the most common type of hair loss in men. Finasteride and dutasteride are oral 5-alpha-reductase inhibitors. This study compared their efficacy and safety in Iranian men with moderate to severe AGA.Methods This ...
Nazila Poostiyan, Zahra Nikyar, Reza Makhmali, Mohsen Hosseini, Zabihollah Shahmoradi   +4 more
doaj   +1 more source

Efficacy of tadalafil treatment on erectile dysfunction in patients under dutasteride treatment: A prospective non-randomized comparative study

Urology Research and Practice, 2019
Objective: In this study, we aimed to evaluate the efficacy of tadalafil in the management of erectile dysfunction in patients under dutasteride medication for bladder outlet obstruction.
Önder Yaman, Mete Özkıdık, Mehmet İlker Gökce   +2 more
doaj   +1 more source

Advances in the Treatment of Androgenetic Alopecia: A Review of Mechanisms and the Clinical Efficacy of Combination Drug Therapy

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Androgenetic alopecia (AGA) is the most prevalent type of hair loss, exerting a significant negative impact on patients' quality of life. The limited efficacy, potential adverse effects, and poor patient adherence of single‐agent therapies highlight substantial unmet needs in clinical management.
Zhuhao Lai, Yi Zhou, Rui Zhou
wiley   +1 more source

การศึกษาประสิทธิศักย์และความปลอดภัยของการใช้ยา dutasteride ขนาดต่ำ ในการรักษาภาวะผมบางจากพันธุกรรมในเพศชาย [PDF]

Currently, finasteride 1 mg/day is the first-line treatment that gives non-improved results in some men with androgenetic alopecia. Dutasteride, in the same drug class, and a dual inhibitor of 5a-reductase, can be used as an alternative. Previous studies

core