Results 71 to 80 of about 4,735 (197)

Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice.

, 2017
Dutasteride is a 5alpha-reductase inhibitor in clinical use to treat endocrine conditions. The present study investigated the neuroprotective mechanisms of action of dutasteride in intact and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned ...
Morissette M, Litim N, Di Paolo T, D. Caruso, R. Melcangi   +4 more
core   +1 more source

Role of dutasteride in pre‐clinical ETS fusion‐positive prostate cancer models [PDF]

, 2012
BACKGROUND Androgens play a crucial role in prostate cancer, hence the androgenic pathway has become an important target of therapeutic intervention.
Pienta, Kenneth J., Cao, Qi, Ateeq, Bushra, Tomlins, Scott A., Lonigro, Robert J., Varambally, Sooryanarayana, Vellaichamy, Adaikkalam, Wang, Rui   +7 more
core   +1 more source

Dutasteride 5α-reductase Inhibitor in the Treatment of Benign Prostatic Hyperplasia: Systematic Review and Meta-analysis

, 2021
Dutasteride is a competitive inhibitor of the enzyme 5-alpha-reductase and is commonly used to treat the symptoms of benign prostatic hyperplasia (BPH).
Romaniuk Maksym, Aksonov Pavlo
core   +1 more source

Quality of Life in Men Treated for Androgenetic Alopecia via a Digital Healthcare Platform: A Retrospective Cohort Study

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Androgenetic alopecia (AGA) is a common chronic condition significantly impacting quality of life (QoL), but few studies have explored treatment outcomes in real‐world digital health settings. Aims The objective of this study is to evaluate the effects of AGA treatment delivered through a digital healthcare platform on patient ...
Angela C. Bersch‐Ferreira, Daniel Reisel, Ashley K. Clift, John C. T. Chao, Hans Johnson, David R. Huang, Hudson Dutra, Gabriel Guimarães   +7 more
wiley   +1 more source

Comparison of Finasteride and Dutasteride on Risk of Prostate Cancer in Patients with Benign Prostatic Hyperplasia: A Pooled Analysis of 15 Real-world Databases

The World Journal of Men's Health
Purpose: Finasteride and dutasteride are used to treat benign prostatic hyperplasia (BPH) and reduce the risk of developing prostate cancer. Finasteride blocks only the type 2 form of 5-alpha-reductase, whereas dutasteride blocks both type 1 and 2 forms
Dae Yul Yang, Won-Woo Seo, Rae Woong Park, Sang Youl Rhee, Jae Myung Cha, Yoon Soo Hah, Chang Won Jeong, Kyung-Jin Kim, Hyeon-Jong Yang, Do Kyung Kim, Ji Yong Ha   +10 more
doaj   +1 more source

Probing the Biological Plausibility of Fluoride as an Endocrine Disruptor

Birth Defects Research, Volume 118, Issue 5, May 2026.
ABSTRACT Background Fluoride has come under recent scrutiny regarding concerns over potential neurodevelopmental and endocrine‐related toxicities, with recent reviews by the National Toxicology Program (NTP) and European Food Safety Authority (EFSA) concluding with moderate or reasonable confidence, respectively, that exposure to drinking water having ...
Ashley M. Mudd, Bladimir J. Ovando, George P. Daston   +2 more
wiley   +1 more source

Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate

, 2009
J Miller, TH TarterSouthern Illinois University School of Medicine, Department of Surgery, Springfield, IL, USAAbstract: Benign prostatic hyperplasia (BPH) is a frequent cause of lower urinary symptoms, with a prevalence of 50% by the sixth decade of ...
J Miller, TH Tarter
core  

Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-analysis

Acta Dermato-Venereologica, 2018
Treatment of male androgenetic alopecia with 5α-reductase inhibitors is efficacious. However, the risk of adverse sexual effects remains controversial.
Solam Lee, Young Bin Lee, Sung Jay Choe, Won-Soo Lee   +3 more
doaj   +1 more source

SUCCESS RATES OF TAMSULOSIN AND DUTASTERIDE AS MEDICAL THERAPY BASED ON IPSS IN SYMPTOMATIC BPH PATIENTS IN ARIFIN ACHMAD HOSPITAL PEKANBARU RIAU

Jurnal Urologi Indonesia, 2018
Objective: To evaluate the success rates of tamsulosin and dutasteride as medical therapy based on international prostate symptom score (IPSS) in symptomatic benign prostatic hyperplasia (BPH) patients. Materials & Methods: We reviewed medical records of 
Zuhirman Zamzami
doaj   +1 more source

The Efficacy of Dutasteride and Green Tea Combination Towards Angiogenesis and Bleeding on BPH after TURP : Study their effect on VEGF, MVD and Hb

International Journal of Science and Engineering, 2015
Objectives: to find the efficacy dutasteride and green tea in reducing hemorrhage on TURP patients  and to evaluate the anti- angiogenesis effect. Methods: Double Blind Randomized Controlled Trial Post Test Only, with 80 samples, randomized into 4 ...
Eriawan Agung Nugroho, Rifki Muslim, Ignatius Riwanto, Soetojo Wirjo Pranoto   +3 more
doaj   +1 more source