Results 111 to 120 of about 3,790 (193)

Identification of compounds that repress DUX4 expression in facioscapulohumeral muscular dystrophy. [PDF]

Sci Rep
Chang N, Moore HP, Himeda CL, O'Brien TE, Thomas W, Roshanravan B, Jones TI, Jones PL.   +7 more
europepmc   +1 more source

The emergence and diversification of the DUX gene family across placental mammals. [PDF]

Commun Biol
Budillon A, Lemmers RJLF, Tapscott SJ, van der Maarel SM.   +3 more
europepmc   +1 more source

KLF18 is a necessary component of the DUX4-initiated transcriptional network and a candidate locus for phenotypic diversity. [PDF]

Genes Dev
Hamm DC, O'Donnell AB, Bennett SR, Lemmers RJLF, van der Vliet PJ, van der Maarel SM, Tapscott SJ.   +6 more
europepmc   +1 more source

Targeting CIC::DUX4 sarcoma with Minnelide in a dual recombinase-initiated genetically engineered mouse model. [PDF]

J Clin Invest
Browne MR, Silver AV, Banerjee R, Dickson BC, Aquino B, Oristian KM, Himes J, Hendrickson PG, Kirsch DG.   +8 more
europepmc   +1 more source

Evaluation of new antisense oligomers targeting the DUX4 mRNA

, 2013
Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common hereditary muscle disorders. Its molecular mechanism involves DNA hypomethylation and chromatin de-repression at the D4Z4 repeat array of chromosome 4q35.
Guckes, Susan M, Harper, Scott Q., Domire, Jacqueline S, Yip, Cassandre, Coppée, Frédérique, Ansseau, Eugénie, Laoudj-Chenivesse, Dalila, Belayew, Alexandra, Tassin, Alexandra, Wallace, Lindsay M, Wilton D., Steve, Vanderplanck, Céline   +11 more
core  

CIC/DUX4 Fusion Gene [PDF]

, 2020
openaire   +1 more source

Successful surgical management of CIC-DUX4 sarcoma of the chest wall. [PDF]

J Surg Case Rep
Bohler F, Chaiyasate M, Waggener JR.
europepmc   +1 more source

Transgenic mouse models for investigating human DUX4 expression during development and its roles in FSHD pathophysiology. [PDF]

Dis Model Mech
Hiramuki Y, Himeda CL, Jones PL, Jones TI.   +3 more
europepmc   +1 more source

Lipid nanoparticle delivery of antisense gapmers attenuates pathology in a mouse model of facioscapulohumeral muscular dystrophy. [PDF]

Mol Ther
Anwar S, Chan KYT, Zia A, Beck SL, Moriyama H, Lim KRQ, Shah MNA, Haque US, Maruyama R, Witzigmann D, Echigoya Y, Bosnakovski D, Kyba M, Cullis PR, Yokota T.   +14 more
europepmc   +1 more source

Modeling of Capicua Family Fusion Oncoprotein-Driven Cancers Reveals Gene-Specific Functionality. [PDF]

Mol Cancer Res
Luck C, Luo Y, Vasileva E, Jacobs KA, Riad J, Macaraig CD, Ponce RKM, Amatruda JF, Okimoto RA.   +8 more
europepmc   +1 more source