Results 121 to 130 of about 2,593 (166)

DUX4-stimulated genes define an antiviral defense program in human placental trophoblasts. [PDF]

J Exp Med
Hatterschide J, Yang L, Coyne CB.
europepmc   +1 more source

Matrix metalloproteinases are hallmark early biomarkers and therapeutic targets in FSHD. [PDF]

JCI Insight
Jung U, Wei E, Ahsan H, Mitanoska A, Chen K, Kyba M, Bosnakovski D.   +6 more
europepmc   +1 more source

All-in-one vectors for epigenetic CRISPR inhibition of <i>DUX4-fl</i> in facioscapulohumeral muscular dystrophy. [PDF]

Mol Ther Methods Clin Dev
Himeda CL, Jones TI, Jones PL.
europepmc   +1 more source

The CIC::DUX4 oncoprotein maintains DNA integrity through direct regulation of the catalytic subunit of DNA polymerase epsilon (POLE). [PDF]

Oncogene
Kosibaty Z, Luck C, Okimoto RA.
europepmc   +1 more source

Estrogen rescues muscle regeneration impaired by DUX4 in a humanized xenograft mouse model. [PDF]

Cell Death Dis
Maiullari S, Mele G, Calandra P, di Blasio G, Valentini S, Torcinaro A, Manni I, Teveroni E, Mancino F, Proietti L, Maiullari F, Pesavento M, Giorgini L, Putti S, Rizzi R, Bortolani S, Scavizzi F, Raspa M, Ricci E, Piaggio G, Gargioli C, Pontecorvi A, Luvisetto S, Mazzone M, Deidda G, Moretti F.   +25 more
europepmc   +1 more source

Biallelic PAX7 variants cause a novel Satellite Cell-opathy with progressive muscle involvement resembling facioscapulohumeral muscular dystrophy. [PDF]

Cell Death Dis
Ganassi M, Strafella C, Savarese M, Heher P, Engquist EN, McGuire L, Johari M, De Nicola GF, Bigot A, Mouly V, Bortolani S, Torchia E, Monforte M, Megalizzi D, Sabino A, Ricci E, Giardina E, Zammit PS, Tasca G.   +18 more
europepmc   +1 more source

CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency, and cell death. [PDF]

Sci Adv
Chammas P, Xie SQ, Sepulveda-Rincon LP, Leeke BJ, Dore MH, Dormann D, Wagner RT, Chang N, Jones PL, Jones PL, McManus MT, Karimi MM, Young G, Percharde M.   +13 more
europepmc   +1 more source

The recent clinical trial of losmapimod for the treatment of facioscapulohumeral muscular dystrophy. [PDF]

Neuromuscul Disord
Bloch RJ, Traficante M, Mariot V, Dumonceaux J.   +3 more
europepmc   +1 more source

First Radiologic Description of CIC-FOXO4 Sarcoma: A Case Report of a Rare and Aggressive Sarcoma and Review of the Literature. [PDF]

Cureus
Nahal A.
europepmc   +1 more source

AAV-shDUX4 provides short-term benefits but limited long-term efficacy in a DUX4 mouse model of FSHD. [PDF]

Mol Ther Methods Clin Dev
Sohn S, Reid S, Bowen M, Hudon C, Corbex E, Morel B, Hourde C, Mariot V, Dumonceaux J.   +8 more
europepmc   +1 more source