Results 161 to 170 of about 17,522 (280)
bioRxiv, 2019 Cytoplasmic dynein is activated by forming a complex with dynactin and the adaptor protein BicD2. We used Interferometric Scattering (iSCAT) microscopy to track dynein-dynactin-BicD2 (DDB) complexes in vitro and developed a regression-based algorithm to ...
Qingzhou Feng, A. Gicking, W. Hancock
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Journal of Biological Chemistry, 2017 Cytoplasmic dynein is the primary minus-end–directed microtubule motor protein in animal cells, performing a wide range of motile activities, including transport of vesicular cargos, mRNAs, viruses, and proteins.
Pedro A. Gutierrez +3 more
semanticscholar +1 more source
Regulation of Dynactin by Palmitoylation
, 2022 Neurons are large, complex cells that use a microtubule motor protein-based system for the fast transport of proteins and organelle cargo throughout long, complex projections. In output projections known as axons, cytoplasmic dynein transports cargo in the retrograde direction towards the cell body.
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Dynactin Subunit p150Glued Isoforms Notable for Differential Interaction with Microtubules [PDF]
, 2009 Olga Zhapparova +7 more
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The mammalian dynein/dynactin complex is a strong opponent to kinesin in a tug-of-war competition
Nature Cell Biology, 2016 Kinesin and dynein motors transport intracellular cargos bidirectionally by pulling them in opposite directions along microtubules, through a process frequently described as a ‘tug of war’. While kinesin produces 6 pN of force, mammalian dynein was found
V. Belyy +5 more
semanticscholar +1 more source
Narcissistic CLIP-170 also attracts dynactin
The Journal of Cell Biology, 2004 ![Graphic][1] Dynactin (red) does not get to the plus end of microtubules (green) that lack CLIP-170 (blue).Self-love of a microtubule binding protein keeps it from its duties, according to Lansbergen et al. ( [page 1003][2]).
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Three-Dimensional Snapshots of the Microtubule-Bound Dynein-Dynactin Complex [PDF]
, 2017 Danielle A. Grotjahn +3 more
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Nature Communications, 2019 LGN and NuMA link epithelial polarity sites with astral microtubules and associate with dynein, but the architecture of such cortical force-generating complexes is unknown.
Laura Pirovano +10 more
doaj +1 more source
mNUDC is required for plus‐end‐directed transport of cytoplasmic dynein and dynactins by kinesin‐1 [PDF]
, 2009 Masami Yamada +12 more
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Gene Expressions Specifically Detected in Motor Neurons (Dynactin 1, Early Growth Response 3, Acetyl-CoA Transporter, Death Receptor 5, and Cyclin C) Differentially Correlate to Pathologic Markers in Sporadic Amyotrophic Lateral Sclerosis [PDF]
, 2007 Yue‐Mei Jiang +10 more
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