Results 41 to 50 of about 59,409 (263)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Supply Chain Capability and Performance Under Environmental Uncertainty: The Mediating Role of Multidimensional Resilience

open access: yesSystems
Global supply chains face unprecedented challenges from geopolitical conflicts, climate change, economic volatility, and technological disruptions, highlighting the critical role of supply chain resilience as a core strategy for firms to maintain ...
Jiaqi Wang, Yanfeng Liu, Jing Li
doaj   +1 more source

Understanding green supply chain information integration on supply chain process ambidexterity: The mediator of dynamic ability and the moderator of leaders’ networking ability

open access: yesFrontiers in Psychology, 2022
Based on dynamic capability theory, this paper aims to explore the influence of green supply chain information integration (IT system integration and information sharing) on supply chain process ambidexterity (efficiency and flexibility) and expounds on ...
Tu Lyu, Yulin Guo, Huan Lin, Huan Lin
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

HOW DYNAMIC CAPABILITIES IMPACT COMPETITIVE ADVANTAGES OF THE HOTEL INDUSTRY? MEDIATING ROLE OF SERVICE INNOVATION CAPABILITY [PDF]

open access: yesGeo Journal of Tourism and Geosites
Despite the growing importance of advanced technology and innovation in the hospitality sector, the wide role of dynamic capabilities in shaping service innovation and sustaining competitive advantage remains underexplored.
Nadra TAWFIG , Kholod AGGAD
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Toward a dynamic capability theory of economic growth

open access: yesIndustrial and Corporate Change, 2019
Abstract New theories of economic growth that are policy-relevant and connect with the histories of success and failure in economic development are urgently needed. This article compares the neoclassical (or market efficiency) school of thought with the production-capability school of thought which included Alexander Hamilton, Friedrich ...
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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