Results 71 to 80 of about 5,248,927 (249)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Real-Time Adaptive Target Tracking via Inverse Kinematics Optimization in Stabilized Systems

IEEE Access
To keep a target item inside their field of view, two-axis gimbal systems are designed to dynamically compensate for any movements that may occur, whether such movements originate from the target itself or from the platform on which the device is mounted.
Abderahman Kriouile, Soufiane Hamida, Oussama El Gannour, Abdoul Latif Abdou Moussa   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Experimental study on population-based incremental learning algorithms for dynamic optimization problems [PDF]

, 2005
Copyright @ Springer-Verlag 2005.Evolutionary algorithms have been widely used for stationary optimization problems. However, the environments of real world problems are often dynamic. This seriously challenges traditional evolutionary algorithms.
Yang, S, Yao, X, Yao, Xin, Yang, Shengxiang   +3 more
core   +1 more source

Indoor Positioning Systems as Critical Infrastructure: An Assessment for Enhanced Location-Based Services

Sensors
As the demand for context-aware services in smart environments continues to rise, Indoor Positioning Systems (IPSs) have evolved from auxiliary technologies into indispensable components of mission-critical infrastructure.
Tesfay Gidey Hailu, Xiansheng Guo, Haonan Si   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

An immune system based genetic algorithm using permutation-based dualism for dynamic traveling salesman problems [PDF]

, 2009
Copyright @ Springer-Verlag Berlin Heidelberg 2009.In recent years, optimization in dynamic environments has attracted a growing interest from the genetic algorithm community due to the importance and practicability in real world applications. This paper
Yang, S, Wang, Dingwei, Shengxiang Yang, Liu, Lili, Lili Liu, Dingwei Wang, Yang, Shengxiang, Wang, D, Liu, L   +8 more
core   +1 more source

An evolutionary algorithm to track changes of optimum value locations in dynamic environments

Journal of Computer Science and Technology, 2004
Non-stationary, or dynamic, problems change over time. There exist a variety of forms of dynamism. The concept of dynamic environments in the context of this paper means that the fitness landscape changes during the run of an evolutionary algorithm ...
Victoria S. Aragón, Susana Cecilia Esquivel   +1 more
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Mastering Requirements Volatility: Strategies for Dynamic Environments and Multiple Stakeholders in Government Software Projects

IEEE Access
Government software projects face challenges due to requirement volatility, dynamic environments, and multiple stakeholders. This study examines these challenges through a case study of the Brazilian National Textbook Program (PNLD) software platform. We
Alenilton Santos Silva, Andre Araujo, Paula Palomino, Rafael Araujo, Diego Dermeval   +4 more
doaj   +1 more source