Results 111 to 120 of about 3,261 (239)

Dynamine alexae

open access: yes, 2017
alexae. Dynamine alexae Peñalver & Grimaldi, 2006 Nymphalidae: Biblidinae. Dominican Republic, Cordillera Septentrional between Santago and Puerto Plata, Dominican Amber; Aquitanian, early Miocene. Depository: AMNH (holotype, DR-18-2). Published figures: Peñalver & Grimaldi (2006: Figs 3–5).
openaire   +2 more sources

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell   +3 more
wiley   +1 more source

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu   +5 more
wiley   +1 more source

Improving Proteolysis‐Targeting Chimera Delivery by Targeting Key Biomarkers in Tumor Endocytosis Pathways

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen   +3 more
wiley   +1 more source

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li   +3 more
wiley   +1 more source

Cell‐Type‐Resolved Proteomics Reveals Distinct Immune and Metabolic Programs Between Primary and Recurrent Ascites in HGSOC

open access: yesPROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.
ABSTRACT High‐grade serous ovarian carcinoma (HGSOC) frequently recurs after platinum–taxane therapy, yet recurrence‐associated changes within ascites remain unclear. We performed cell‐type‐resolved quantitative proteomics on paired ascites samples collected at primary diagnosis and at disease recurrence from three HGSOC patients, profiling unsorted ...
Bo Ren   +6 more
wiley   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, Volume 117, Issue 3, Page 642-652, September 2026.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

The role of clathrin in post‐Golgi secretion in plant cells

open access: yesNew Phytologist, Volume 251, Issue 6, Page 3401-3417, September 2026.
Morphology of Arabidopsis thaliana XVE»amiCHC seedlings. Summary Within the plant endomembrane system, the vesicle coat protein clathrin localizes to the plasma membrane (PM) and the trans‐Golgi Network/early endosome (TGN/EE). While the role of clathrin in endocytosis at the PM is well established, its function at TGN/EE, presumably in late secretion (
Maciek Adamowski   +4 more
wiley   +1 more source

Integrating Lateral Super‐Resolution and Axial Progression Reveals Distinct Clathrin Pit Formation Pathways

open access: yesTraffic, Volume 27, Issue 3, September 2026.
Variable‐angle total internal reflection fluorescence structured illumination microscopy (vaTIRF‐SIM) links nanoscale lateral organization with axial progression during clathrin‐mediated endocytosis. Super‐resolved TIRF‐SIM images resolve the lateral architecture of AP2‐labeled clathrin coats, while corresponding Z‐index maps report relative axial ...
Cristopher Thompson   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy