Results 201 to 210 of about 5,717 (230)

Dynein Structure and Function

Annual Review of Cell Biology, 1989
Article de synthese sur les proteines associees aux microtubules, dont la dyneine.
M E, Porter, K A, Johnson
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Cytoplasmic dynein in neurodegeneration

Pharmacology & Therapeutics, 2011
Cytoplasmic dynein 1 (later referred to as dynein) is the major molecular motor moving cargoes such as mitochondria, organelles and proteins towards the minus end of microtubules. Dynein is involved in multiple basic cellular functions, such as mitosis, autophagy and structure of endoplasmic reticulum and Golgi, but also in neuron specific functions in
Judith, Eschbach, Luc, Dupuis
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The molecular anatomy of dynein

Essays in Biochemistry, 2000
Recent molecular, genetic and functional studies have led to an unparalleled growth in our understanding of dynein and the roles played by the various polypeptides of these massive macromolecular assemblies. Dyneins are highly complex 1-2MDa complexes that function as molecular motor and move the cargo to which they are attached towards the minus-end ...
A, Harrison, S M, King
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Multi‐Dynein hypothesis

Cell Motility, 1995
Axonemal dyneins and cytoplasmic dynein have evolved separate strategies to perform their tasks. The multi-dynein hypothesis accurately describes the highly specialized axonemal isoforms; each isoform is encoded by a separate gene, is located in a precise place, produces specific forces which contribute to the overall generation of propagated bending ...
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Structural comparison of purified dynein proteins with in situ dynein arms

Journal of Molecular Biology, 1984
Using the quick-freeze deep-etch technique, we describe the structure of outerarm dynein proteins from Chlamydomonas and Tetrahymena after adsorption to a mica surface, after high-salt dissociation, and after glutaraldehyde fixation, and compare these images to the configuration of outer arms bound to microtubules.
U, Goodenough, J, Heuser
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Dynein branches out

Nature Cell Biology, 2008
Individual neurons form specific elaborate dendritic structures that receive presynaptic information. The pattern of dendritic branching is regulated by the microtubule-associated motor protein dynein, which is responsible for the transport of essential endosomes and other organelles into the dendrites.
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Role of dynein and kinesin in viral proliferation & dynein inhibitors

2022
Dynein and kinesin are motor proteins involved in the retrograde and anterograde, respectively, transport of cargoes, including viral genomes following infection. Current literature reveals that both proteins play critical roles in ensuring successful viral proliferation.
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Pathway of the Microtubule-Dynein ATPase and the Structure of Dynein: A Comparison with Actomyosin

Annual Review of Biophysics and Biomolecular Structure, 1985
Dynein and myosin show several important similarities in design as well as some interesting differences in detail. Both ATPases function as crossbridges that undergo microscopic movements to drive the sliding of filaments, which results in macroscopic movements. They share a common design employing globular heads attached to flexible strands. Each head
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Purification of Axonemal Dyneins and Dynein-Associated Components from Chlamydomonas

2009
Axonemal dyneins are responsible for generating the force required to power ciliary and flagellar motility. These highly complex enzymes form the inner and outer arms associated with the outer doublet microtubules. They are built around one or more ~520kD heavy chains that exhibit motor activity and also include additional components that are required ...
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Axonemal dyneins

Current Opinion in Cell Biology, 1992
George B Witman
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