Results 1 to 10 of about 9,142 (164)

A basal body microtubule singlet-to-doublet transition in Plasmodium male gametogenesis [PDF]

open access: yesNature Communications
Axoneme assembly constitutes a pivotal process in male gametogenesis of Plasmodium. Plasmodium possesses a unique nuclear envelope-anchored basal body that templates axoneme assembly, distinct from the basal body that templates the axoneme of cilia or ...
Shuzhen Yang   +8 more
doaj   +2 more sources

ANKEF1 is a key axonemal component essential for murine sperm motility and male fertility [PDF]

open access: yeseLife
Sperm motility is essential for male fertility and depends on the structural integrity of the sperm axoneme, which features a canonical ‘9 + 2’ microtubule arrangement.
Shuntai Yu   +10 more
doaj   +2 more sources

The axoneme of the spider spermatozoon

open access: yesBollettino Di Zoologia, 1995
Abstract The axoneme of the spider spermatozoon (Pholcus sp.) has been examined after fixation with a fixative that permits the visualization of the individual protofilaments. The axoneme was found to consist of nine microtubular doublets in a circle around three microtubular singlets, thus a 9 + 3 pattern.
Romano Dallai, Wojciech Witaliński
exaly   +2 more sources

Proteome of the central apparatus of a ciliary axoneme [PDF]

open access: yesJournal of Cell Biology, 2019
Nearly all motile cilia have a “9+2” axoneme containing a central apparatus (CA), consisting of two central microtubules with projections, that is essential for motility. To date, only 22 proteins are known to be CA components. To identify new candidate CA proteins, we used mass spectrometry to compare axonemes of wild-type Chlamydomonas and a CA-less ...
Lei Zhao   +2 more
exaly   +4 more sources

Correction: Divergent Plasmodium kinases drive MTOC, kinetochore, and axoneme organisation in male gametogenesis [PDF]

open access: yesLife Science Alliance
This study reveals how Plasmodium kinases regulate MTOC, axoneme and kinetochore organisation in male gametogenesis, providing key insights into potential targets for malaria transmission control.
Ryuji Yanase   +8 more
doaj   +2 more sources

Proteomic and structural comparison between cilia from primary ciliary dyskinesia patients with a DNAH5 defect [PDF]

open access: yesFrontiers in Molecular Biosciences
IntroductionPrimary ciliary dyskinesia (PCD) is a genetic disorder affecting motile cilia across various organs, leading to recurrent respiratory infections, subfertility, and laterality defects.
Charlotte de Ceuninck van Capelle   +13 more
doaj   +2 more sources

Predicting the locations of force-generating dyneins in beating cilia and flagella

open access: yesFrontiers in Cell and Developmental Biology, 2022
Cilia and flagella are slender cylindrical organelles whose bending waves propel cells through fluids and drive fluids across epithelia. The bending waves are generated by dynein motor proteins, ATPases whose force-generating activity changes over time ...
Jonathon Howard   +7 more
doaj   +1 more source

Structure of the trypanosome paraflagellar rod and insights into non-planar motility of eukaryotic cells

open access: yesCell Discovery, 2021
Eukaryotic flagella (synonymous with cilia) rely on a microtubule-based axoneme, together with accessory filaments to carryout motility and signaling functions. While axoneme structures are well characterized, 3D ultrastructure of accessory filaments and
Jiayan Zhang   +8 more
doaj   +1 more source

Flagellar energetics from high-resolution imaging of beating patterns in tethered mouse sperm

open access: yeseLife, 2021
We demonstrate a technique for investigating the energetics of flagella or cilia. We record the planar beating of tethered mouse sperm at high resolution. Beating waveforms are reconstructed using proper orthogonal decomposition of the centerline tangent-
Ashwin Nandagiri   +7 more
doaj   +1 more source

The Ancient and Evolved Mouse Sperm-Associated Antigen 6 Genes Have Different Biologic Functions In Vivo

open access: yesCells, 2022
Sperm-associated antigen 6 (SPAG6) is the mammalian orthologue of Chlamydomonas PF16, an axonemal central pair protein involved in flagellar motility. In mice, two Spag6 genes have been identified.
Yi Tian Yap   +10 more
doaj   +1 more source

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