Results 11 to 20 of about 12,013 (227)
Microbial Cell, 2014 Centrin is an evolutionarily conserved EF-hand calcium-binding protein found in the centriole of animals and the basal body of flagellated organisms. It was originally discovered in the flagellated unicellular green alga Chlamydomonas reinhardtii, where ...
Ziyin Li
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Proteome of the central apparatus of a ciliary axoneme [PDF]
Journal of Cell Biology, 2019 Nearly all motile cilia have a “9+2” axoneme containing a central apparatus (CA), consisting of two central microtubules with projections, that is essential for motility. To date, only 22 proteins are known to be CA components. To identify new candidate CA proteins, we used mass spectrometry to compare axonemes of wild-type Chlamydomonas and a CA-less ...
Lei Zhao, Yuqing Hou, George Witman
exaly +4 more sources
Axoneme Structure from Motile Cilia [PDF]
Cold Spring Harbor Perspectives in Biology, 2016 The axoneme is the main extracellular part of cilia and flagella in eukaryotes. It consists of a microtubule cytoskeleton, which normally comprises nine doublets. In motile cilia, dynein ATPase motor proteins generate sliding motions between adjacent microtubules, which are integrated into a well-orchestrated beating or rotational motion.
Ishikawa, Takashi (author)
openaire +5 more sources
Proteins with proximal-distal asymmetries in axoneme localisation control flagellum beat frequency [PDF]
Nature CommunicationsThe 9 + 2 microtubule-based axoneme within motile flagella is well known for its symmetry. However, examples of asymmetric structures and proteins asymmetrically positioned within the 9 + 2 axoneme architecture have been identified.
Cecile Fort +3 more
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Correction: Divergent Plasmodium kinases drive MTOC, kinetochore, and axoneme organisation in male gametogenesis [PDF]
Life Science AllianceThis study reveals how Plasmodium kinases regulate MTOC, axoneme and kinetochore organisation in male gametogenesis, providing key insights into potential targets for malaria transmission control.
Ryuji Yanase +8 more
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The axoneme of the spider spermatozoon
Bollettino Di Zoologia, 1995 Abstract The axoneme of the spider spermatozoon (Pholcus sp.) has been examined after fixation with a fixative that permits the visualization of the individual protofilaments. The axoneme was found to consist of nine microtubular doublets in a circle around three microtubular singlets, thus a 9 + 3 pattern.
Romano Dallai +2 more
exaly +2 more sources
A basal body microtubule singlet-to-doublet transition in Plasmodium male gametogenesis [PDF]
Nature CommunicationsAxoneme assembly constitutes a pivotal process in male gametogenesis of Plasmodium. Plasmodium possesses a unique nuclear envelope-anchored basal body that templates axoneme assembly, distinct from the basal body that templates the axoneme of cilia or ...
Shuzhen Yang +8 more
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ANKEF1 is a key axonemal component essential for murine sperm motility and male fertility [PDF]
eLifeSperm motility is essential for male fertility and depends on the structural integrity of the sperm axoneme, which features a canonical ‘9 + 2’ microtubule arrangement.
Shuntai Yu +10 more
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Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies. [PDF]
J Cell Commun SignalThis review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Zhang Q +7 more
europepmc +2 more sources
Predicting the locations of force-generating dyneins in beating cilia and flagella
Frontiers in Cell and Developmental Biology, 2022 Cilia and flagella are slender cylindrical organelles whose bending waves propel cells through fluids and drive fluids across epithelia. The bending waves are generated by dynein motor proteins, ATPases whose force-generating activity changes over time ...
Jonathon Howard +7 more
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