Mechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysis [PDF]
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting 5–20% of reproductive-age women. However, the treatment of PCOS is mainly based on symptoms and not on its pathophysiology.
Gita Pratama +6 more
doaj +2 more sources
Kappa opioid receptor and dynorphin signaling in the central amygdala regulates alcohol intake
Dipanwita Pati +2 more
exaly +3 more sources
Structural basis of divergent substrate recognition and inhibition of human neurolysin [PDF]
A zinc metallopeptidase neurolysin (Nln) processes diverse bioactive peptides to regulate signaling in the mammalian nervous system. To understand how Nln interacts with various peptides with dissimilar sequences, we determined crystal structures of Nln ...
Ke Shi +7 more
doaj +2 more sources
Altered expression of kisspeptin, dynorphin, and related neuropeptides in polycystic ovary syndrome: A cross-sectional study [PDF]
Background: Since kisspeptin (KISS1) in the hypothalamus is affected by the inhibitory effect of dynorphin, it raises questions about the controlled balance of these 2 neuropeptides in women with and without polycystic ovary syndrome (PCOS).
Andon Hestiantoro +7 more
doaj +2 more sources
Influence of neurokinin B, dynorphin A and kisspeptin-10 on <i>in vitro</i> gonadotropin secretion by anterior pituitary cells isolated from pubescent ewes. [PDF]
Szysiak N +7 more
europepmc +3 more sources
Kisspeptin/Neurokinin B/Dynorphin (KNDy) cells as integrators of diverse internal and external cues: evidence from viral-based monosynaptic tract-tracing in mice [PDF]
Aleisha M Moore, Lique M Coolen
exaly +2 more sources
Functional interaction between orexin/dynorphin transmission in the posterior paraventricular nucleus of the thalamus following alcohol dependence: mediation of alcohol-seeking behavior. [PDF]
Flores-Ramirez FJ +2 more
europepmc +3 more sources
Food and the brain: Neural and endocrine control of feeding, metabolism, and reproduction. [PDF]
Abstract Feeding and reproductive function are regulated by intricate systems that monitor food availability and energy stores, and on the basis of energy status, promote or put a brake on reproduction. This is particularly evident in the systems that regulate feeding and reproductive state in female mammals.
da Silva Mansano N, Lieu CV, Abizaid A.
europepmc +2 more sources
SEQUENCE ANALYSIS SUGGESTS POSITIVE SELECTION ON THE BOVINE PRODYNORPHIN GENE [PDF]
Dynorphin A is an endogenous opioid peptide that is part of the KNDy system in the hypothalamus of mammals. This peptide acts as an inhibitor of the GnRH pulse generation, thus regulating the onset of puberty and reproductive cycles.
Suqueli García M.F. +2 more
doaj +1 more source

