Results 51 to 60 of about 18,857 (274)

Avian opioid peptides: evolutionary considerations, functional roles and a challenge to address critical questions

open access: yesFrontiers in Physiology, 2023
The present review considers the putative hormonal opioid peptides in birds. In birds and all other vertebrates, there are four opioid related genes encoding a series of peptides.
Krystyna Pierzchała-Koziec   +1 more
doaj   +1 more source

Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice

open access: yesJournal of Neuroinflammation, 2012
Background The striato-nigral projecting pathway contains the highest concentrations of dynorphin in the brain. The functional role of this opioid peptide in the regulation of mesencephalic dopaminergic (DAergic) neurons is not clear.
Wang Qingshan   +8 more
doaj   +1 more source

Acetaldehyde involvement in ethanol's postabsortive effects during early ontogeny [PDF]

open access: yes, 2013
Clinical and biomedical studies sustains the notion that early ontogeny is a vulnerable window to the impact of alcohol. Experiences with the drug during these stages increase latter disposition to prefer, use or abuse ethanol.
Abate, Paula   +2 more
core   +1 more source

The role of BDNF/TrkB signaling in acute amphetamine-induced locomotor activity and opioid peptide gene expression in the rat dorsal striatum

open access: yesFrontiers in Systems Neuroscience, 2011
Exposure to psychostimulants increases brain-derived neurotrophic factor (BDNF) mRNA and protein levels in the cerebral cortex and subcortical structures.
Jacqueline F McGinty   +3 more
doaj   +1 more source

A role for transcriptional repressor methyl-CpG-binding protein 2 and plasticity-related gene serum- and glucocorticoid-inducible kinase 1 in the induction of inflammatory pain states [PDF]

open access: yes, 2007
Activity-dependent changes in neurons of the rat superficial dorsal horn are crucial for the induction and maintenance of neuropathic and inflammatory pain states.
Geranton, SM   +2 more
core   +1 more source

Estradiol treatment prevents injury induced enhancement in spinal cord dynorphin expression.

open access: yesFrontiers in Physiology, 2012
Administration of the ovarian steroid estradiol in male and female animals has been shown to have neuromodulatory and neuroprotective effects in a variety of experimental models. In the present study, spinal tissues from dermatomes just above (T5-7, at
Daya S. Gupta, Charles H. Hubscher
doaj   +1 more source

Involvement of the Opioid Peptide Family in Cancer Progression

open access: yesBiomedicines, 2023
Peptides mediate cancer progression favoring the mitogenesis, migration, and invasion of tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating angiogenesis/lymphangiogenesis.
Manuel Lisardo Sánchez   +2 more
doaj   +1 more source

Ester hydrolysis differentially reduces aconitine-induced anti-hypersensitivity and acute neurotoxicity: Involvement of spinal microglial dynorphin expression and implications for Aconitum processing

open access: yesFrontiers in Pharmacology, 2016
Aconitines, including bulleyaconitine A, probably the most bioactive and abundant alkaloids in Aconitum plant, are a group of diester C19-diterpenoid alkaloids with one acetylester group attached to C8 of the diterpenoid skeleton and one benzoylester ...
Teng-Fei Li, Yong-Xiang Wang, Nian Gong
doaj   +1 more source

Neuropeptide co-expression in hypothalamic kisspeptin neurons of laboratory animals and the human

open access: yesFrontiers in Neuroscience, 2015
Hypothalamic peptidergic neurons using kisspeptin (KP) and its co-transmitters for communication are critically involved in the regulation of mammalian reproduction and puberty.
Katalin eSkrapits   +6 more
doaj   +1 more source

Isolation and amino acid sequence analysis of a 4,000-dalton dynorphin from porcine pituitary [PDF]

open access: yes, 1982
A 4,000-dalton dynorphin was isolated from porcine pituitary. It has 32 amino acids (Mr = 3,986), with the previously described heptadecapeptide (now called dynorphin A) at its amino terminus and a related tridecapeptide, dynorphin B, at its carboxyl ...
Fischli, Walter   +3 more
core  

Home - About - Disclaimer - Privacy