Results 51 to 60 of about 11,182 (207)
Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. [PDF]
Peptidergic neurons synthesizing kisspeptin (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus have been implicated in negative sex steroid feedback to GnRH neurons. In laboratory rodents, testosterone decreases KP and NKB expression in
Herczeg, László +11 more
core +1 more source
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho +8 more
wiley +1 more source
Acute hypothalamic–pituitary–ovarian axis suppression is common in anti‐NMDAR encephalitis, yet ovarian function and fertility recover favorably even in teratoma‐associated cases, supporting reassuring long‐term reproductive prognoses. Abstract Introduction Anti‐N‐methyl‐D‐aspartate receptor (anti‐NMDAR) encephalitis predominantly affects women of ...
Jia Wang +4 more
wiley +1 more source
Uma Nova visão da participação dos receptores B1 e B2 para cininas na dor neuropática orofacial [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011Embora pouco prevalente entre a população, a neuralgia do trigêmeo é uma das condições mais dolorosas.
Luiz, Ana Paula
core
Maladaptive responses to stress are a hallmark of alcohol use disorder, but the mechanisms that underlie this are not well characterized. Here, we show that kappa opioid receptor signaling in the bed nucleus of the stria terminalis (BNST) is a critical ...
Lara S Hwa +11 more
doaj +1 more source
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan +3 more
wiley +1 more source
Secondary structure transitions and aggregation induced in dynorphin neuropeptides by the detergent sodium dodecyl sulfate [PDF]
Dynorphins, endogeneous opioid neuropeptides, function as ligands to the opioid kappa receptors and also induce non-opioid effects in neurons, probably related to direct membrane interactions. We have characterized the structure transitions of dynorphins
Perálvarez-Marín, Alex, +3 more
core +2 more sources
A symmetric systemic challenge elicits a right‐biased response mediated by vasopressin signaling
Water deprivation, a spatially symmetric homeostatic challenge, induces vasopressin receptor‐dependent right‐sided hindlimb asymmetry in rats, providing a binary readout of lateralized physiological regulation. These findings suggest that symmetric homeostatic challenges can engage neuroendocrine mechanisms that shift the balance between left‐ and ...
Hiroyuki Watanabe +10 more
wiley +1 more source
Bradykinin Receptors Mediate Dynorphin Pronociceptive Action To Produce Persistent Pain
Intrathecal injection of dynorphin or des-Tyr-dynorphin fragments, which do not bind to opioid receptors, produce tactile and thermal hypersensitivity in rodents.
Chen, Qingmin
core +4 more sources
Abstract INTRODUCTION Neural network and bioenergetic abnormalities occur with Alzheimer's disease (AD) pathogenesis. METHODS We explored mossy fiber (MF) and mitoenergetic alteration using ɑ‐smooth muscle actin (ɑSMA) and cytochrome c oxidase (COX) immunolabeling in human hippocampus relative to tangle and plaque formation by referring to Braak (0–VI)
Tian Tu +11 more
wiley +1 more source

