Results 141 to 150 of about 2,342 (192)
International Review of Neurobiology, 2009 Dynorphins, the endogenous opioid peptides derived from prodynorphin may participate not only in the inhibition, but also in facilitation of spinal nociceptive transmission.
Koichi Tan-No +2 more
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Differential Metabolism of Dynorphins in Substantia Nigra, Striatum, and Hippocampus
Peptides, 1997 To map the proteolytic enzymes metabolizing dynorphins in brain structures, size-exclusion chromatography linked to electrospray ionization mass spectrometry was used. Enzymes extracted from rat hippocampus, striatum, and substantia nigra were tested for
Johan Sandin +2 more
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Neuropeptides, 2016 Dynorphins are important neuropeptides with a central role in nociception and pain alleviation. Many mechanisms regulate endogenous dynorphin concentrations, including proteolysis.
Francis Beaudry
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Annual Review of Pharmacology and Toxicology, 1988
Like other opioids, the dynorphins play a role in wide variety of physiological parameters, including pain regulation, motor activity, cardiovascular regulation, respiration, temperature regulation, feeding behavior, hormone balance, and the response to shock or stress. The dynorphins are unusual if not unique, however, in that they frequently modulate
A P, Smith, N M, Lee
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Like other opioids, the dynorphins play a role in wide variety of physiological parameters, including pain regulation, motor activity, cardiovascular regulation, respiration, temperature regulation, feeding behavior, hormone balance, and the response to shock or stress. The dynorphins are unusual if not unique, however, in that they frequently modulate
A P, Smith, N M, Lee
openaire +3 more sources
Progress in Neurobiology, 1996
Studies on dynorphin involvement in epilepsy are summarised in this review. Electrophysiological, biochemical and pharmacological data support the hypothesis that dynorphin is implicated in specific types of seizures. There is clear evidence that this is true for complex partial (limbic) seizures, i.e.
Simonato M., Romualdi P.
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Studies on dynorphin involvement in epilepsy are summarised in this review. Electrophysiological, biochemical and pharmacological data support the hypothesis that dynorphin is implicated in specific types of seizures. There is clear evidence that this is true for complex partial (limbic) seizures, i.e.
Simonato M., Romualdi P.
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Nonopiate Effects of Dynorphin and Des-Tyr-Dynorphin
Science, 1982Intracerebroventricular administration of dynorphin produced potent and long-lasting effects on motor function and the electroencephalogram in rats. In addition, local iontophoretic or pressure ejection of dynorphin consistently inhibited hippocampal unit activity.
J M, Walker +4 more
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PROCESSING OF DYNORPHINS IN THE STRIATO-NIGRAL PATHWAY
Analgesia (Elmsford, N Y ), 1995 Jerzy Silberring, Íngrid Nylander
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Biochemical and Biophysical Research Communications, 1983
Rimorphin (dynorphin B) has been demonstrated to exist together with alpha-neo-endorphin and dynorphin(1-17) (dynorphin A) in the human hypothalamus. The content of rimorphin was comparable to that of alpha-neo-endorphin and somewhat higher than that of dynorphin. This result is quite similar to the recent observations in bovine, porcine and rat neural
K, Nakao +6 more
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Rimorphin (dynorphin B) has been demonstrated to exist together with alpha-neo-endorphin and dynorphin(1-17) (dynorphin A) in the human hypothalamus. The content of rimorphin was comparable to that of alpha-neo-endorphin and somewhat higher than that of dynorphin. This result is quite similar to the recent observations in bovine, porcine and rat neural
K, Nakao +6 more
openaire +2 more sources