Results 41 to 50 of about 495 (105)

Comparison of Hemostatic Activity in Canine Leukoreduced Cryoprecipitate, Cryopoor Plasma, and Fresh Plasma

Veterinary Clinical Pathology, Volume 54, Issue 2, Page 120-131, June 2025.
ABSTRACT Background To date, no studies have reported the evaluation of hemostatic activity in canine leukoreduced cryoprecipitate (LR‐CRYO) and leukoreduced cryopoor plasma (LR‐CPP). Objectives We aimed to compare the hemostatic activity of LR‐CRYO and LR‐CPP to leukoreduced fresh plasma (LR‐FP) and to evaluate the preservation of LR‐CRYO by ...
Roberta Perego, Eva Spada, Luciana Baggiani, Giuliano Ravasio, Enrica Zucca, Graziella Vanosi, Giancarlo Ruffo, Daniela Proverbio   +7 more
wiley   +1 more source

Implications of the c.1201C > G (p.Arg401Gly) mutation in FGG gene on fibrinogen stability and function

Frontiers in Medicine
Congenital dysfibrinogenemia, a rare coagulation disorder characterized by decreased fibrinogen activity while antigen level is usually normal. We conducted a study on a three-generation family comprising 15 members, among whom three individuals were ...
Jingyi Lu, Zeyi Xiang, Yonglong Ye, Wei Chen, Jieyi Tan, Bin Kuang, Jun Liu   +6 more
doaj   +1 more source

Identification of Risk Factors and Predictive Indicators for Tigecycline‐Associated Hypofibrinogenemia

Clinical and Translational Science, Volume 18, Issue 4, April 2025.
ABSTRACT To investigate the prevalence, clinical manifestations, and risk factors of hypofibrinogenemia after tigecycline use, which can disrupt coagulation and potentially hinder antimicrobial therapy. This observational study was conducted from January to December 2021 at a tertiary general hospital in China.
Xiaohui Liu, Xuefeng Yuan, Long Wen, Xin Tan, Qian Sui, Jiheng Liu   +5 more
wiley   +1 more source

A newly detected c.180 + 1G > A variant causes a decrease of FGA transcription in patients with congenital hypo-dysfibrinogenemia [PDF]

, 2022
Zhe Li, Jintu Lou, Wei Li, Lin Chen
openalex   +1 more source

Validating the Online Self‐Administered Bleeding Assessment Tool (Self‐BAT) as a Screening Tool for Bleeding Disorders

Haemophilia, Volume 32, Issue 1, Page 324-327, January/February 2026.
Veronica DeYoung, Julie Grabell, Wilma Hopman, Megan Chaigneau, Maria Avgeropoulos, Paula James   +5 more
wiley   +1 more source

Dysfibrinogenemia and hypofibrinogenemia - Spectrum of pathogenic variants in Slovak patients

Biomedical Papers
Introduction. Congenital hypofibrinogenemia (CH) and congenital dysfibrinogenemia (CD) are rare coagulation disorders caused by quantitative or qualitative defects in the fibrinogen gene.
Dominika Jaraskova, Jan Chandoga, Angelika Batorova, Tatiana Prigancova, Miriama Juhosova, Pavol Durina, Alzbeta Vavrova, Silvia Dallemule, Robert Petrovic, Anna Kyselova, Denisa Jankovicova, Daniel Bohmer   +11 more
doaj   +1 more source

Fibrinogen post‐translational modifications are biochemical determinants of fibrin clot properties and interactions

The FEBS Journal, Volume 292, Issue 1, Page 11-27, January 2025.
The biochemical and biophysical properties of fibrinogen and fibrin, which is formed during coagulation, are critical for proper hemostatic function. The formation of abnormal fibrin clots has been linked to a prothrombotic phenotype and disease states.
Margarita Tenopoulou
wiley   +1 more source

Hemostatic Balance in Pediatric Acute Liver Failure: Epidemiology of Bleeding and Thrombosis, Physiology, and Current Strategies

Frontiers in Pediatrics, 2020
Pediatric Acute Liver Failure (PALF) is a rapidly progressive clinical syndrome encountered in the pediatric ICU which may rapidly progress to multi-organ dysfunction, and on occasion to life threatening cerebral edema and hemorrhage.
Yonca Bulut, Anil Sapru, Gavin D. Roach
doaj   +1 more source

How to investigate mild to moderate bleeding disorders and bleeding disorder of unknown cause

International Journal of Laboratory Hematology, Volume 46, Issue S1, Page 27-33, May 2024.
Abstract A bleeding tendency is one of the most common complaints observed by hematologists. It is challenging to differentiate a clinically insignificant bleeding from a bleeding phenotype that requires hemostatic evaluation and medical intervention. A thorough review of personal and familial history, objective assessment of bleeding severity using a ...
Alessandro Casini, Johanna Gebhart
wiley   +1 more source

Acquired hypofibrinogenemia: current perspectives

Journal of Blood Medicine, 2016
Martin W Besser,1 Stephen G MacDonald2 1Department of Haematology, 2Department of Specialist Haemostasis, The Pathology Partnership, Addenbrooke’s Hospital, Cambridge, UK Abstract: Acquired hypofibrinogenemia is most frequently caused by ...
Besser MW, MacDonald SG
doaj