Results 81 to 90 of about 190,206 (302)
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Cancer Communications, EarlyView.Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan +13 more
wiley +1 more source
Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
Prevalence and pattern of dyslipidemia in Nepalese individuals with type 2 diabetes
BMC Research Notes, 2017 Background Atherogenic dyslipidemia is an important modifiable risk factor for cardiovascular disease among patients of type 2 diabetes mellitus.
Daya Ram Pokharel +7 more
doaj +1 more source
Hepatology, EarlyView., 2022 Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef +5 more
wiley +1 more source
Hepatology, EarlyView., 2022 The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol +22 more
wiley +1 more source
EBioMedicine, 2018 Background: Severe hypertriglyceridemia (SHTG, TG ≥5·65 mmol/L), a disease, usually resulting from a combination of genetic and environmental factors, may increase the risk of acute pancreatitis (AP).
Jing-Lu Jin +11 more
doaj
Asian Journal of Medical Sciences, 2019 Background: India has seen an ever increasing number of diabetic patients and in turn rise in cardiovascular diseases. Many studies have shown diabetic patients to have dyslipidemia, with certain common patterns early in the disease.
Vinay Krishnamurthy +2 more
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background There have been no prior reports of detailed evaluations using intravascular imaging during Jetstream treatment. Aims This study, therefore, aimed to investigate the effects of calcification characteristics and wire bias on lumen gain in Jetstream atherectomy using optical frequency domain imaging (OFDI). Methods This study enrolled
Koji Kuroda +10 more
wiley +1 more source
Incidence and 1‐Year Prognostic of Unstable Angina After High‐Sensitivity Troponin Assessment
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Incidence and prognostic of unstable angina after high‐sensitivity troponin assesment is controversial. Aims This study evaluated prognostic of a contemporary population of patients with UA defined using high sensitive T troponin (T hs‐cTn) measurements and with significant coronary artery disease (CAD). Methods Consecutive patients
Romain Jouen +10 more
wiley +1 more source