Results 151 to 160 of about 59,671 (341)
The repair capacity spectrum of human skeletal muscle injury from sports to surgical trauma settings
The Journal of Physiology, EarlyView.Abstract figure legend The interplay between current knowledge, treatment strategies and remaining unsolved clinical challenges in optimising clinical outcomes for patients suffering skeletal muscle tissue injury. In particular the outcome for strain injuries and acute extremity compartment syndrome remains poor, despite extensive work in animal models.
Grith Højfeldt +3 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend This study investigated the effects of volitional exercise on muscle health in the more severe D2.mdx model of Duchenne muscular dystrophy (DMD). We showed that 8–10 weeks of a relatively high volume of voluntary wheel running (VWR) in D2.mdx animals augmented select muscle mass and normalized ex vivo muscle force compared to ...
Stephanie R. Mattina +7 more
wiley +1 more source
Binding sites involved in the interaction of actin with the N‐terminal region of dystrophin [PDF]
, 1992 Barry A. Levine +3 more
openalex +1 more source
Dietary nitrate supplementation mitigates age‐related changes at the neuromuscular junction in mice
The Journal of Physiology, EarlyView.Abstract figure legend Ageing is associated with a decline in muscle mass and strength, namely sarcopenia, significantly impacting the quality of life in older individuals. Different strategies are being explored to counteract these detrimental effects. In the present study, we investigated a non‐invasive nutritional approach: the impact of 2 months of
Maira Rossi +9 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Thirty‐four participants underwent muscle damage (electrically stimulated eccentric contractions) triggering regenerative processes following myofiber necrosis. Participants were treated for 10 days cold (CWI) (15 min, 12{degree sign}C), thermoneutral (TWI) (30 min, 32{degree sign}C) or hot (HWI) (60 min, 42{degree sign}C) water ...
Valentin Dablainville +15 more
wiley +1 more source
Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis
Scientific Reports, 2017 Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder resulting from mutations in the dystrophin gene. The mdx/utrn −/− mouse, lacking in both dystrophin and its autosomal homologue utrophin, is commonly used to model the clinical symptoms of
Hung-Chih Chen +6 more
doaj +1 more source
Corticosteroid therapy in Duchenne muscular dystrophy: Management and new insights
Developmental Medicine &Child Neurology, EarlyView.
Claudia Brogna, Eugenio Mercuri
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo +11 more
wiley +1 more source
NMR in Biomedicine, Volume 38, Issue 11, November 2025.Biomarkers for muscle disease activity are needed for trials in Becker muscular dystrophy (BMD). We investigated magnesium (Mg2+), phosphodiesters (PDE) and pH from 31P‐MRS; and membrane permeability from random permeable barrier model (RBPM) diffusion as candidates, studying ‘preserved’ and ‘progressing’ muscles in patients with BMD versus controls ...
Esther J. Schrama +5 more
wiley +1 more source
The subcellular distribution of dystrophin in mouse skeletal, cardiac, and smooth muscle. [PDF]
, 1991 T J Byers +2 more
openalex +1 more source