Results 161 to 170 of about 59,671 (341)

Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke

open access: yesBrain Pathology, Volume 35, Issue 6, November 2025.
After ischemic stroke, TRPV4 activation induces cerebral edema through the TRPV4‐RhoA‐MMP9 axis: RhoA upregulates MMP9, which cleaves β‐DG to impair membrane anchoring. Subsequent β‐DG loss triggers AQP4 depolarization, disrupting GS‐mediated water homeostasis.
Yongchuan Li   +13 more
wiley   +1 more source

Direct visualization of the dystrophin network on skeletal muscle fiber membrane. [PDF]

open access: bronze, 1992
Volker Straub   +3 more
openalex   +1 more source

Estrogen‐Related Receptor Alpha Promotes Skeletal Muscle Regeneration and Mitigates Muscular Dystrophy

open access: yesThe FASEB Journal, Volume 39, Issue 19, 15 October 2025.
ERRα promotes muscle regeneration. ERRα drives angiogenic and mitochondrial metabolic gene program in proliferating and differentiating myogenic cells. ERRα also induces myogenic factor genes such as MyoG. Through these pathways ERRα promotes muscle regeneration in the skeletal muscle in acute injury and chronic myopathy.
Thi Thu Hao Nguyen   +8 more
wiley   +1 more source

Identification of a novel first exon in the human dystrophin gene and of a new promoter located more than 500 kb upstream of the nearest known promoter. [PDF]

open access: bronze, 1994
Hisahide Nishio   +9 more
openalex   +1 more source

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 10, Page 2136-2151, October 2025.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó   +17 more
wiley   +1 more source

Localization of dystrophin gene transcripts during mouse embryogenesis. [PDF]

open access: bronze, 1992
Denis Houzelstein   +3 more
openalex   +1 more source

Filamented Light (FLight) Bioprinting of Mini‐Muscles with Self‐Renewal Potential

open access: yesAdvanced Materials, Volume 37, Issue 40, October 9, 2025.
This work presents the FLight biofabrication for engineering in vitro muscle constructs by photocrosslinking pristine collagen and fibrinogen using ruthenium. The resulting mini‐muscles retain in vivo‐like tissue organization and a Pax7⁺ cell pool.
Hao Liu   +8 more
wiley   +1 more source

Dystrophin is phosphorylated by endogenous protein kinases [PDF]

open access: green, 1993
Monica De Luise   +8 more
openalex   +1 more source

DNA‐Based Hydrogels for Musculoskeletal Reconstruction: Harnessing Dynamic Programmability and Multimodal Therapeutic Integration

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
DNA‐based hydrogels serve dual roles as structural scaffolds and therapeutic platforms, offering innovative solutions for musculoskeletal regeneration with multifunctional abilities. Abstract Musculoskeletal disorders, including bone fractures, osteoarthritis, and muscle injuries, represent a leading cause of global disability, revealing the urgency ...
Ruijianghan Shi   +4 more
wiley   +1 more source

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