Results 161 to 170 of about 59,671 (341)
After ischemic stroke, TRPV4 activation induces cerebral edema through the TRPV4‐RhoA‐MMP9 axis: RhoA upregulates MMP9, which cleaves β‐DG to impair membrane anchoring. Subsequent β‐DG loss triggers AQP4 depolarization, disrupting GS‐mediated water homeostasis.
Yongchuan Li +13 more
wiley +1 more source
Direct visualization of the dystrophin network on skeletal muscle fiber membrane. [PDF]
Volker Straub +3 more
openalex +1 more source
ERRα promotes muscle regeneration. ERRα drives angiogenic and mitochondrial metabolic gene program in proliferating and differentiating myogenic cells. ERRα also induces myogenic factor genes such as MyoG. Through these pathways ERRα promotes muscle regeneration in the skeletal muscle in acute injury and chronic myopathy.
Thi Thu Hao Nguyen +8 more
wiley +1 more source
Identification of a novel first exon in the human dystrophin gene and of a new promoter located more than 500 kb upstream of the nearest known promoter. [PDF]
Hisahide Nishio +9 more
openalex +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó +17 more
wiley +1 more source
Localization of dystrophin gene transcripts during mouse embryogenesis. [PDF]
Denis Houzelstein +3 more
openalex +1 more source
Filamented Light (FLight) Bioprinting of Mini‐Muscles with Self‐Renewal Potential
This work presents the FLight biofabrication for engineering in vitro muscle constructs by photocrosslinking pristine collagen and fibrinogen using ruthenium. The resulting mini‐muscles retain in vivo‐like tissue organization and a Pax7⁺ cell pool.
Hao Liu +8 more
wiley +1 more source
Dystrophin is phosphorylated by endogenous protein kinases [PDF]
Monica De Luise +8 more
openalex +1 more source
DNA‐based hydrogels serve dual roles as structural scaffolds and therapeutic platforms, offering innovative solutions for musculoskeletal regeneration with multifunctional abilities. Abstract Musculoskeletal disorders, including bone fractures, osteoarthritis, and muscle injuries, represent a leading cause of global disability, revealing the urgency ...
Ruijianghan Shi +4 more
wiley +1 more source
Isolation and characterization of different C-terminal fragments of dystrophin expressed in Escherichia coli [PDF]
R E Milner +2 more
openalex +1 more source

