Results 171 to 180 of about 59,671 (341)

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy

Science, 2016
Chengzu Long, L. Amoasii, A. Mireault, John R. McAnally, Hui Li, E. Sánchez-Ortiz, Samadrita Bhattacharyya, J. Shelton, R. Bassel-Duby, E. Olson   +9 more
semanticscholar   +1 more source

MyomiRs Expression in Limb Girdle Muscular Dystrophy

IUBMB Life, Volume 77, Issue 10, October 2025.
ABSTRACT This manuscript is a comprehensive review focused on the role of microRNAs (miRs)—short RNA molecules—in Limb Girdle Muscular Dystrophy (LGMD). LGMD encompasses various and heterogeneous rare genetic neuromuscular diseases, characterized by the progressive wasting and deterioration of muscle fibers, predominantly affecting the pelvic and ...
G. Breveglieri, M. T. Altieri, M. T. Rodia, R. Costa, F. Frabetti, G. Cenacchi, G. Sabbioni, M. Borgatti   +7 more
wiley   +1 more source

Myotubes from transgenic mdx mice expressing full-length dystrophin show normal calcium regulation. [PDF]

, 1994
W F Denetclaw, F. Woodward Hopf, Gregory A. Cox, Jeffrey S. Chamberlain, Richard A. Steinhardt   +4 more
openalex   +1 more source

Characterization of Muscle Tissue Cell Diversity and Clinical Implications in Idiopathic Inflammatory Myopathy

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Idiopathic inflammatory myopathies (IIMs) exhibit diverse cellular microenvironments in muscle tissues, yet the full spectrum of cell populations and changes remains unclear. This study aimed to characterize cellular heterogeneity, explore cell–cell interactions and assess the prognostic value of cell subtype abundances across IIM ...
Honglin Zhu, Yizhi Xiao, Shasha Xie, Qiming Meng, Ting Ding, Ting Huang, Di Liu, Sijia Liu, Xiaoli Zhang, Huali Zhang, Hui Luo   +10 more
wiley   +1 more source

Dystrophin in a membrane skeletal network: localization and comparison to other proteins [PDF]

, 1993
GM Dmytrenko, D W Pumplin, RJ Bloch
openalex   +1 more source

Immunoproteasome Inhibition Positively Impacts the Gut‐Muscle Axis in Duchenne Muscular Dystrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Duchenne Muscular Dystrophy (DMD) features immune‐muscle crosstalk, where muscle fibre degeneration enhances pro‐inflammatory macrophage infiltration, worsening inflammation and impairing regeneration. Methods We investigated the impact of immunoproteasome (IP) inhibition on the gut‐muscle axis in mdx mice, a well‐established model ...
Andrea Farini, Francesco Strati, Monica Molinaro, Debora Mostosi, Sabrina Saccone, Luana Tripodi, Jacopo Troisi, Annamaria Landolfi, Chiara Amoroso, Barbara Cassani, Aitor Blanco‐Míguez, Emma Leonetti, Davide Bazzani, Mattia Bolzan, Francesco Fortunato, Flavio Caprioli, Federica Facciotti, Yvan Torrente   +17 more
wiley   +1 more source

<b>Dense immunostainings on both neuromuscular and myotendon junctions with an anti-dystrophin monoclonal </b><b>anfibody </b>

, 1989
Teruo Shimizu, Kiichiro Matsumura, Yoshihide Sunada, Toru Mannen   +3 more
openalex   +2 more sources

Non-isotopic analysis of single strand conformation polymorphism (SSCP) in the exon 13 region of the human dystrophin gene. [PDF]

, 1993
Uwe Lenk, R. Hanke, U Kraft, K Grade, Ingrid Grunewald, Andreas Speer   +5 more
openalex   +1 more source

Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy

Molecular Therapy, 2018
D. Duan
semanticscholar   +1 more source

Preterm Birth Conditions Alter Muscle Stem Cells and Their Niche, Causing Lasting Impairments in Muscle Regeneration and Function

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Preterm birth‐related conditions affect the development of multiple organs, such as the heart, the lungs and the brain, leading to long‐term alterations in their function and a higher risk of comorbidities. Emerging evidence also indicates that the skeletal muscles are affected. We aimed to understand the mechanisms underlying these
Alyson Deprez, Thomas Molina, Gael Cagnone, Pauline Garcia, Séverine Leclerc, Anik Cloutier, Rebecca Desaulniers, Benjamin Ellezam, Anne Monique Nuyt, Nicolas A. Dumont   +9 more
wiley   +1 more source