Results 11 to 20 of about 18,651,759 (343)

Association of quantitative analysis of intratumoral reduced E-cadherin expression with lymph node metastasis and prognosis in patients with breast cancer

Scientific Reports, 2023
Loss of E-cadherin expression is a poor prognostic factor in patients with breast cancer. Breast cancer cells co-cultured with adipocytes reportedly promote E-cadherin attenuation and tumor progression.
Xiangyue Meng, Michi Morita, Sayaka Kuba, Hiroko Hayashi, Ryota Otsubo, Megumi Matsumoto, Kosho Yamanouchi, Kazuma Kobayashi, Akihiko Soyama, Masaaki Hidaka, Kengo Kanetaka, Takeshi Nagayasu, Susumu Eguchi   +12 more
doaj   +1 more source

CD148 tyrosine phosphatase promotes cadherin cell adhesion. [PDF]

PLoS ONE, 2014
CD148 is a transmembrane tyrosine phosphatase that is expressed at cell junctions. Recent studies have shown that CD148 associates with the cadherin/catenin complex and p120 catenin (p120) may serve as a substrate.
Keiko Takahashi, Anton Matafonov, Katherine Sumarriva, Hideyuki Ito, Colette Lauhan, Dana Zemel, Nobuo Tsuboi, Jin Chen, Albert Reynolds, Takamune Takahashi   +9 more
doaj   +1 more source

E-Cadherin Orthologues as Substrates for the Serine Protease High Temperature Requirement A (HtrA)

Biomolecules, 2022
Helicobacter pylori (H. pylori) expresses the serine protease and chaperone High temperature requirement A (HtrA) that is involved in periplasmic unfolded protein stress response. Additionally, H.
Sabine Bernegger, Evelyn Hutterer, Urszula Zarzecka, Thomas P. Schmidt, Markus Huemer, Isabella Widlroither, Gernot Posselt, Joanna Skorko-Glonek, Silja Wessler   +8 more
doaj   +1 more source

Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance

Nature Communications, 2023
E-cadherin is an essential cell‒cell adhesion protein that mediates canonical cadherin-catenin complex formation in epithelial lateral membranes.
Chao Kong, Xiaozhan Qu, Mingming Liu, Weiya Xu, Da Chen, Yanshen Zhang, Shan Zhang, Feng Zhu, Zhenbang Liu, Jianchao Li, Chengdong Huang, Chao Wang   +11 more
doaj   +1 more source

E-Cadherin expression in human tumors: a tissue microarray study on 10,851 tumors

Biomarker Research, 2021
Background The E-Cadherin gene (CDH1, Cadherin 1), located at 16q22.1 encodes for a calcium-dependent membranous glycoprotein with an important role in cellular adhesion and polarity maintenance.
Eike Burandt, Felix Lübbersmeyer, Natalia Gorbokon, Franziska Büscheck, Andreas M. Luebke, Anne Menz, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Sören Weidemann, Christoph Fraune, Katharina Möller, Frank Jacobsen, Patrick Lebok, Till Sebastian Clauditz, Guido Sauter, Ronald Simon, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Sarah Minner, Rainer Krech, David Dum, Till Krech, Andreas Holger Marx, Christian Bernreuther   +26 more
doaj   +1 more source

ZEB1 is Negatively Correlated with E-Cadherin in Prostatic Anomaly Tissue

MCBS (Molecular and Cellular Biomedical Sciences), 2022
Background: Prostatic anomalies are common in tumor or infection condition. The enlargement of prostate gland affects the epithelial cell polarity that involves epithelial-mesenchymal transition (EMT).
Sari Eka Pratiwi, Sri Nuryani Wahyuningrum, Rachmagreta Perdana Putri, Danarto Danarto, Didik Setyo Heriyanto, Nur Arfian, Sofia Mubarika Haryana, Indwiani Astuti   +7 more
doaj   +1 more source

Dual role of E-cadherin in cancer cells

Tissue Barriers, 2021
E-cadherin is the main component of epithelial adherens junctions (AJs), which play a crucial role in the maintenance of stable cell–cell adhesion and overall tissue integrity.
S. N. Rubtsova, I. Zhitnyak, N. Gloushankova   +2 more
semanticscholar   +1 more source

The deep infiltrating endometriosis tissue has lower T-cadherin, E-cadherin, progesterone receptor and oestrogen receptor than endometrioma tissue

Taiwanese Journal of Obstetrics & Gynecology, 2021
Objective: To compare the T-cadherin, E-cadherin, PR and ER staining levels of deep infiltrating endometriosis (DIE) tissue, ovarian endometriomas and normal endometrial tissues. Materials and methods: DIE tissue of 24 cases, endometrioma of 30 cases and
Ismail Biyik, Uzeyir Kalkan, Sercan Simsek   +2 more
doaj   +1 more source

The Role of Epithelial and Vascular-Endothelial Cadherin in the Differentiation and Maintance of Tissue Integrity

Acta Medica, 2001
The present review has focused on the cell adhesion molecules from the cadherin superfamily, in particular on E- and VE-cadherin. In general, cadherins are a large group of cell adhesion molecules located at intercellular junctions called adherent ...
Petr Nachtigal, Andrea Gojová, Vladimír Semecký   +2 more
doaj   +1 more source

Vimentin is a potential prognostic factor for tongue squamous cell carcinoma among five epithelial-mesenchymal transition-related proteins. [PDF]

PLoS ONE, 2017
We aimed to investigate the association of the expression levels of five epithelial-mesenchymal transition (EMT)-related proteins (Snail, Twist, E-cadherin, N-cadherin, and Vimentin) with tumorigenesis, pathologic parameters and prognosis in tongue ...
Pei-Feng Liu, Bor-Hwang Kang, Yi-Min Wu, Ju-Hsin Sun, Liang-Ming Yen, Ting-Ying Fu, Yun-Chung Lin, Huei-Han Liou, Yaoh-Shiang Lin, Huei-Cin Sie, I-Chien Hsieh, Yu-Kai Tseng, Chih-Wen Shu, Yao-Dung Hsieh, Luo-Ping Ger   +14 more
doaj   +1 more source