Results 41 to 50 of about 18,651,759 (343)

Covalent and density-controlled surface immobilization of E-cadherin for adhesion force spectroscopy.

open access: yesPLoS ONE, 2014
E-cadherin is a key cell-cell adhesion molecule but the impact of receptor density and the precise contribution of individual cadherin ectodomains in promoting cell adhesion are only incompletely understood.
Dagmar Fichtner   +8 more
doaj   +1 more source

E-cadherin is transcriptionally activated via suppression of ZEB1 transcriptional repressor by small RNA-mediated gene silencing. [PDF]

open access: yesPLoS ONE, 2011
RNA activation has been reported to be induced by small interfering RNAs (siRNAs) that act on the promoters of several genes containing E-cadherin. In this study, we present an alternative mechanism of E-cadherin activation in human PC-3 cells by siRNAs ...
Minami Mazda   +3 more
doaj   +1 more source

E-cadherin, guardian of liver physiology [PDF]

open access: yesClinics and Research in Hepatology and Gastroenterology, 2015
E-cadherin is a cell-to-cell adhesion molecule involved in epithelial cell behavior, tissue formation and cancer suppression. In the liver, E-cadherin is expressed by hepatocytes and biliary epithelial cells. However, the exact role of E-cadherin in hepatic pathophysiology remains largely unknown.
Gonzalez-Sanchez, Ester   +3 more
openaire   +3 more sources

Expression of e-cadherin, n-cadherin and snail and their correlation with clinicopathological variants: an immunohistochemical study of 132 invasive ductal breast carcinomas in Egypt

open access: yesClinics, 2011
OBJECTIVE: To evaluate the expression of the cell adhesion molecules E-cadherin and N-cadherin and the transcription factor Snail in invasive ductal breast carcinomas and to determine their relationships with clinicopathological features.
Hanan Mohamed Abd ElMoneim   +1 more
doaj   +1 more source

E-cadherin expression in thymomas

open access: yesYonsei Medical Journal, 1998
For the purpose of investigating the pattern of E-cadherin (E-CD) expression in thymomas, 72 cases were immunostained using monoclonal antibody (HECD-1) and microwave-enhanced immunohistochemical method on formalin-fixed, paraffin-embedded tissue sections. The thymomas were classified according to modified Müller-Hermelink classification.
W I, Yang   +3 more
openaire   +3 more sources

E-Cadherin Engagement Stimulates Tyrosine Phosphorylation [PDF]

open access: yesCell Adhesion and Communication, 1997
Cadherins are cell adhesion molecules concentrated at intercellular adherens junctions, where they form a multiprotein complex with cytoplasmic catenins. Although cell-cell interactions affect many aspects of cell behavior, little is known about signaling pathways triggered by cadherin engagement.
M S, Kinch   +3 more
openaire   +2 more sources

Transcriptional repression of E-cadherin by human papillomavirus type 16 E6. [PDF]

open access: yesPLoS ONE, 2012
There is increasing evidence supporting DNA virus regulation of the cell adhesion and tumour suppressor protein, E-cadherin. We previously reported that loss of E-cadherin in human papillomavirus (HPV) type 16-infected epidermis is contributed to by the ...
Zarina J D'Costa   +5 more
doaj   +1 more source

Characterizing interactions in E-cadherin assemblages

open access: yesBiophysical Journal, 2023
Cadherin intermolecular interactions are critical for cell-cell adhesion and play essential roles in tissue formation and the maintenance of tissue structures. In this study, we focus on E-cadherin, a classical cadherin that connects epithelial cells, to understand how they interact in cis and trans conformations when attached to the same cell or ...
Sayane Shome   +3 more
openaire   +4 more sources

Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model. [PDF]

open access: yesPLoS ONE, 2016
Tight regulation of cadherin-mediated intercellular adhesions is critical to both tissue morphogenesis during development and tissue homeostasis in adults.
Stephanie L Maiden   +2 more
doaj   +1 more source

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