Results 91 to 100 of about 24,019 (278)
Difficoltà in matematica: percorsi di autoformazione in e-learning
My PhD thesis enters the sphere of the studies which aims at the integration between the outcomes of the research on mathematical education and the outcomes of the research about e-learning. Particularly, the thesis inquires and discusses the potentialities of self assessment in e-learning modality through routs built from the analysis of errors that ...
openaire +2 more sources
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
In occasione dell'accordo tra il MAXXI Museo delle Arti del XXI secolo e “Sapienza Università di Roma” firmato dalla Direttrice Giovanna Melandri e il Magnifico Rettore Eugenio Gaudio è stata avviata una proficua collaborazione tra due delle ...
Luca Ribichini
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ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Noetica e semiotica nell’apprendimento della matematica
Apprendere la matematica è un procxesso multiforme e complesso, in nessun modo il risultato diretto dell'insegnamento. Dal gli anni 60 Guy Brousseau a posto le basi per una disciplina che oggi è autonoma e e ben fondata, anche se ancora in costruzione.
D'AMORE, BRUNO
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Este artigo propõe uma articulação entre a Perspectiva de Sistemas para o estudo da criatividade, de Csikszentmihalyi, e a Teoria das Situações Didáticas, no campo da matemática, de Brousseau. Consideramos que a articulação das duas teorias possibilita o
Cleyton Hércules Gontijo +2 more
doaj
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Apprendere la matematica facendo matematica
Il rapporto tra la sistemazione formale della matematica, così come viene presentata nei testi e nei manuali, e i processi di comprensione e apprendimento dei ragazzi, visto attraverso le autoanalisi di alcuni grandi matematici del XX ...
BOLONDI, GIORGIO
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