Results 141 to 150 of about 78,400 (265)
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source
Prediyabette erken ateroskleroz belirteci e-selectin
, 2021 INTRODUCTION: Activation of endothelial dysfunction cascade and procoagulant pathways are one of the main pathophysiological mechanisms that leads to beta cell dysfunction, insulin resistance and vascular complications in prediabetes and diabetes. The present study aimed to investigate the relation between E-selectin and carotid intima media thickness (
Öztürk, İlknur Ünsal +4 more
openaire +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Oxidative Stress Induces E-Selectin Expression through Repression of Endothelial Transcription Factor ERG. [PDF]
J Immunol, 2023 Zhang J +8 more
europepmc +1 more source
PAR1 Agonists Stimulate APC-Like Endothelial Cytoprotection and Confer Resistance to Thromboinflammatory Injury [PDF]
, 2018 Stimulation of protease-activated receptor 1 (PAR1) on endothelium by activated protein C (APC) is protective in several animal models of disease, and APC has been used clinically in severe sepsis and wound healing.
Aisiku, Omozuanvbo +10 more
core +1 more source
Adjunctive Therapies in Periodontitis: Current Concepts and the Future
Journal of Periodontal Research, EarlyView.This graphical abstract summarizes the translational pathway from preclinical research to clinical implementation of adjunctive therapies for periodontitis, highlighting key barriers, innovative therapeutic strategies, and emerging tools that aim to bridge experimental discoveries with patient care.
Rafael Scaf de Molon +4 more
wiley +1 more source
The biology of E-selectin ligands in leukemogenesis. [PDF]
Adv Cancer Res, 2023 Ales E, Sackstein R.
europepmc +1 more source
Transfusion, EarlyView.Abstract Background Traumatic brain injury (TBI) carries significant mortality and morbidity in civilian and military populations. Current treatment guidelines for TBI are primarily supportive, and no pharmacological agent exists to attenuate the progression of brain injury.
Maxime A. Visa +9 more
wiley +1 more source
Plasma levels of E-selectin are associated with retinopathy in sickle cell disease. [PDF]
Eur J Haematol, 2023 Agouti I +11 more
europepmc +1 more source