Results 161 to 170 of about 21,662,479 (296)

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

E-selectin, but not CRP, partially mediates the association between metabolic indices and insulin resistance in older adults: a mediation analysis. [PDF]

Asian Biomed (Res Rev News)
Ashour L, Albweitel T, Rahmeh JA, Alfawadleh M, El Sharabi A, Shareah RA, Alomari Z, Alhawwari A, Alkalouti M, Al-Nawaiseh NF, Ababneh MS, Kaoukji A.   +11 more
europepmc   +1 more source

Allopurinol increased the risk of COVID-19 hospitalization mediated by E-Selectin downregulation. [PDF]

J Infect, 2023
Zhang K, Chen R, Jiang Q.
europepmc   +1 more source

Pulsed Electric Field Processing Enhances the Endothelial Bioefficacy of Red Beet (Beta vulgaris L.) Extracts by Restoring Endothelial Nitric Oxide Synthase–Nitric Oxide Signaling in High‐Fat Diet Rats

eFood, Volume 7, Issue 4, August 2026.
Pulsed electric field (PEF) processing qualitatively reshapes the phytochemical profile of red beet extracts, resulting in enhanced endothelial bioefficacy. Compared with conventional extraction, PEF‐treated extracts more effectively restore nitric oxide signaling, suppress endothelial inflammation, and normalize vascular structure in high‐fat diet ...
Eunju Jang, Tae‐Baek Lee, Lisa Tonini, Soobin Choi, YoonA Jeon, Taehyun Kim, Taeyoung Kang, Hyuk‐Joon Choi, Changhwan Ahn   +8 more
wiley   +1 more source

Altered DNA methylation of the ABO gene is associated with differential plasma levels of von willebrand factor and E-selectin. [PDF]

Transfusion
Lou T, Sugrue JA, Patin E, Milieu Intérieur Consortium, Quintana-Murci L, Duffy D, O'Farrelly C.   +6 more
europepmc   +1 more source

siRNA Lipid-Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy. [PDF]

Cell Mol Bioeng, 2023
Figueroa-Espada CG, Guimarães PPG, Riley RS, Xue L, Wang K, Mitchell MJ.   +5 more
europepmc   +1 more source

Implications of the E-selectin S128R mutation for drug discovery

, 2017
The C-type lectin E-selectin mediates the rolling of circulating leukocytes on vascular endothelial cells during the inflammatory process. In numerous studies, the S128R mutation of the E-selectin was associated with cardiovascular and autoimmune ...
Rabbani, Said, Preston, Roland C., Binder, Florian P C., Moes, Suzette, Magnani, John L., Ernst, Beat   +5 more
core  

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

TNF-α and E-Selectin as Valuable Biomarkers in Patients with Acute Coronary Artery Syndrome. [PDF]

Int J Mol Cell Med
Auda HJ, Barakat AM, Sachet HS, Aboqader RF, Thamer AT.   +4 more
europepmc   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source