Results 181 to 190 of about 52,137 (255)

Endothelial Atypical Receptors for Chemoattractants in Lung Immune Surveillance

European Journal of Immunology, Volume 56, Issue 8, August 2026.
Control of chemokine gradients within tissues is achieved by atypical chemokine receptors (ACKRs). The lungs require tightly regulated leukocyte recruitment for effective host defense while preventing tissue damage. In this context, ACKRs expressed by lung endothelial cells are emerging as critical regulators of leukocyte trafficking and inflammatory ...
Mattia Laffranchi, Eleonora Bonanni, Francesca Sozio, Miriam Turchetti, Giuseppe Sciumè, Marcus Thelen, Annalisa Del Prete, Raffaella Bonecchi, Silvano Sozzani   +8 more
wiley   +1 more source

Codon-Optimized and de novo-Synthesized E-Selectin/AAV2 Dose-Response Study for Vascular Regeneration Gene Therapy. [PDF]

Ann Surg
Voza FA, Byrne BJ, Ortiz YY, Li Y, Le N, Osafo L, Ribieras AC, Shao H, Huerta CT, Wei Y, Falero-Diaz G, Franco-Bravo A, Lassance-Soares RM, Vazquez-Padron RI, Liu ZJ, Velazquez OC.   +15 more
europepmc   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Corrigendum to "Depletion of ß1,6-N-acetylglucosaminyltransferase reduces E-selectin binding capacity and migratory potential of human gastrointestinal adenocarcinoma cells" [Neoplasia 59 (2024) 10183]. [PDF]

Neoplasia
Staffeldt L, Maar H, Beimdiek J, Chambers S, Riecken K, von Itzstein M, Buettner FF, Everest-Dass A, Lange T.   +8 more
europepmc   +1 more source

Tumour‐Derived Extracellular Vesicles Containing dsRNA Induce Degradation of Ribosomal Protein mRNA in Platelets

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
ABSTRACT Extracellular vesicles (EVs) mediate intercellular communication within the tumour microenvironment by carrying cargoes from paracrine parent cells. EVs have attracted great research interest for their ability to carry nucleic acids into recipient cells and modulate cellular functions.
Gaoge Sun, Yuhuan Tao, Zihan Liu, Kaixiang Zhang, Shuai Zuo, Shanwen Chen, Shufang Ning, Tianyi Zhang, Pengyuan Wang, Ying Zhang, Zhi John Lu, Hang Hubert Yin   +11 more
wiley   +1 more source

Tacrolimus versus hydrocortisone in management of atopic dermatitis in children, a randomized controlled double-blind study: New insights on TARC, CTACK, TSLP, and E-selectin. [PDF]

Immun Inflamm Dis
Binsaleh AY, Kotkata FA, Bahaa MM, Hamouda AO, El-Gammal MA, Elberri AI, Selim HM, El-Samongy MA, Hamouda MA, Mokhtar FA, Fahmy SA, Elmasri TA, Elberri EI.   +12 more
europepmc   +1 more source

Shear‐Activated von Willebrand Factor Captures Extracellular Vesicles to Promote Platelet Activation and Metastasis

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
Under shear flow, stretched vWF captures platelets and EVs, and TF‐positive EVs amplify platelet activation and aggregation. Although tumour cells do not bind vWF directly, the resulting microthrombi trap circulating tumour cells and promote metastatic progression.
Yuanyuan Wang, Xiaobo Liu, Pascal Nakielski, Katrin Nekipelov, Amanda Salviano‐Silva, Alper Topuz, Alexander T. Bauer, Julian Kött, Jannis Akrivakis, Santra Brenna, Tomasz Downar, Neus Feliu, Gerd Bendas, Berta Puig, Stefan W. Schneider, Dmitry A. Fedosov, Christian Gorzelanny   +16 more
wiley   +1 more source

Analysis of ICAM-1 rs3093030, VCAM-1 rs3783605, and E-Selectin rs1805193 Polymorphisms in African Women Living with HIV and Preeclampsia. [PDF]

Int J Mol Sci
Sibiya S, Mlambo ZP, Mthembu MH, Mkhwanazi NP, Naicker T.   +4 more
europepmc   +1 more source

Altered MicroRNA Signatures in Circulating Extracellular Vesicles Reflect Aortic Dilation in Takayasu Arteritis

Journal of Extracellular Biology, Volume 5, Issue 8, August 2026.
ABSTRACT Takayasu arteritis (TAK) is a large‐vessel vasculitis that can lead to aneurysmal dilation, yet reliable circulating biomarkers for vascular remodelling remain lacking. Extracellular vesicles (EVs) carry miRNAs implicated in vascular biology, but their relevance to TAK has not been fully explored. Circulating EVs were isolated from serum of 54
Kohei Kawajiri, Shun Nakagama, Tetsuo Sasano, Yasuhiro Maejima   +3 more
wiley   +1 more source