This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang +13 more
wiley +1 more source
Are Advanced Glycation End-Products and Skin Autofluorescence Associated with E-Selectin and Pulse Wave Velocity as Markers of Atherosclerosis Risk in Children with Obesity? [PDF]
Medyńska A, Noczyńska A, Zwolińska D.
europepmc +1 more source
Inflammation Control and Tumor Growth Inhibition of Ovarian Cancer by Targeting Adhesion Molecules of E-Selectin. [PDF]
Yang B, Yin S, Zhou Z, Huang L, Xi M.
europepmc +1 more source
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang +8 more
wiley +1 more source
Restricted human CD45 isoglycoforms serve as functional E-selectin ligands and delineate hematopoietic maturity. [PDF]
Ales E, Sackstein R.
europepmc +1 more source
Computationally guided conversion of the specificity of E-selectin to mimic that of Siglec-8. [PDF]
Wang X, Hanes MS, Cummings RD, Woods RJ.
europepmc +1 more source
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang +6 more
wiley +1 more source
Vasculoprotective role of del Nido cardioplegia in open-heart surgery via modulation of E-Selectin, Endocan, and TNF-alpha coronary sinus blood samples. [PDF]
Kızılyel F +7 more
europepmc +1 more source
E-Selectin/AAV Gene Therapy Promotes Myogenesis and Skeletal Muscle Recovery in a Mouse Hindlimb Ischemia Model. [PDF]
Ribieras AJ +9 more
europepmc +1 more source
Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang +7 more
wiley +1 more source

