Results 211 to 220 of about 52,137 (255)

Harnessing upregulated E-selectin while enhancing SDF-1α sensing redirects infused NK cells to the AML-perturbed bone marrow. [PDF]

Leukemia
Sanz-Ortega L, Andersson A, Carlsten M.
europepmc   +1 more source

Psoriatic Neutrophils Are Primed in Circulation for Enhanced β₂-Integrin-Dependent Recruitment and Effector Function on E-Selectin and ICAM-1. [PDF]

J Invest Dermatol
Garcia G, Chen SJ, Westerland MR, Wu X, Hwang ST, Simon SI.   +5 more
europepmc   +1 more source

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Soluble E-Selectin in Arthritis

Clinical Immunology and Immunopathology, 1993
Cellular adhesion molecules, such as E-selectin, function to recruit leukocytes into inflammatory lesions. Recently, a soluble form of this adhesion molecule, sE-selectin, has been described. In this study we determined soluble E-selectin (sE-selectin) in synovial fluid (SF) and blood samples from patients with rheumatoid arthritis (RA) and other ...
A E, Koch, W, Turkiewicz, L A, Harlow, R M, Pope   +3 more
openaire   +2 more sources

E-Selectin Binding Promotes Neutrophil Activationin Vivoin E-Selectin Transgenic Mice

Biochemical and Biophysical Research Communications, 1996
E-selectin is a membrane protein expressed by endothelial cells activated by cytokines released during the inflammatory process; it plays an important role in neutrophil emigration into inflamed tissues. To further explore in vivo the function of E-selectin, we have generated transgenic mouse line expressing E-selectin under the control of a chicken ...
Araki, Masatake, Araki, Kimi, Miyazaki, Y., Iwamoto, Masahiro, Izui, Shozo, Yamamura, K., Vassalli, Pierre   +6 more
openaire   +4 more sources

Conformation of the oligosaccharide receptor for E‐selectin

Biopolymers, 1994
AbstractA tetrasaccharide related to the blood group oligosaccharides, known as sialyl LewisX, has been proposed as the receptor for the lectin responsible for leukocyte adhesion named alternatively as E‐selectin or ELAM‐1. The 13C‐ and 1H‐nmr spectra have been completely assigned for a tetrasaccharide model of this receptor, Neu5Ac α‐(2 → 3)‐Gal β‐(1 →
C, Mukhopadhyay, K E, Miller, C A, Bush
openaire   +2 more sources

Selective E-selectin ligands

Blood, 2013
In this issue of Blood, Sreeramkumar and colleagues report that E-selectin ligand-1 (ESL-1) is a highly selective ligand for E-selectin on hematopoietic progenitors with unexpected important contributions to their trafficking.
openaire   +2 more sources

Synthesis of a Potent Antagonist of E-Selectin

The Journal of Organic Chemistry, 2002
A synthesis of an antagonist of E-selectin previously reported by a group at Novartis Pharma in Basel is described. An important feature involves the formation of an ether linkage based on a Rh(II)-catalyzed reaction. Stereocontrolled glycosylations rely on the anomeric activation of 2-pyridylthio carbonate as leaving group for the attachment of beta-D-
Stephen, Hanessian, Vincent, Mascitti, Olivier, Rogel   +2 more
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A Ligand Binding Assay for E-Selectin

Analytical Biochemistry, 1994
We describe here a cell-free ligand binding assay for E-selectin. The assay involves immobilizing soluble E-selection onto microtiter plates and incubating with 125I-labeled carcinoembryonic antigen (CEA) which carries the tetrasaccharide sialyl Lewis x (sLex). The bound CEA is eluted by ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N',-tetraacetic
M, Anostario, S H, Li, K S, Huang
openaire   +2 more sources

Neutrophils roll on E-selectin.

The Journal of Immunology, 1993
Abstract Using flow conditions that simulate those in post capillary venules, we have found that neutrophils attach and roll on a substrate bearing purified E-selectin. E-selectin resembles P-selectin (CD62) with regard to the dependence of attachment efficiency on wall shear stress and selectin density.
M B, Lawrence, T A, Springer
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Potential Significance of Circulating E-Selectin

Circulation, 1997
In the accompanying article, Belch and colleagues1 propose a model in which baseline levels of serum E-selectin (CD62E) are predictive of restenosis after percutaneous transluminal angioplasty in patients with peripheral arterial occlusive disease. Their data revealed significantly higher baseline serum E-selectin levels in patients who restenosed ...
openaire   +2 more sources