Results 211 to 220 of about 21,662,479 (296)

Landscape of Immune Remodeling and NAP1L1‐Driven Epithelial Reprogramming in Gastric Cancer Metastasis

open access: yesChronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 126-138, June 2026.
High‐resolution single‐cell atlas of normal gastric tissue, primary gastric cancer, and metastatic lesions. (A) Schematic diagram of experimental design. (B) Bar plot for qualified cell numbers in each lesion. (C) Cells annotation by canon markers for all cells. (D) Bubble chart for canon marker genes for each cell subtype.
Min Sun   +3 more
wiley   +1 more source

Adjunctive Methylprednisolone After Thrombectomy: A Secondary Analysis Stratified by Admission White Blood Cell Count

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Admission WBC identified who benefited from adjunctive methylprednisolone after thrombectomy. Improved 90‐day function and lower mortality/pneumonia occurred only with WBC ≥ 10 × 109/L, supporting WBC‐guided corticosteroid targeting. ABSTRACT Background Leukocyte‐driven inflammation may contribute to reperfusion–outcome mismatch after thrombectomy.
Chengsong Yue   +9 more
wiley   +1 more source

Codon-Optimized and de novo-Synthesized E-Selectin/AAV2 Dose-Response Study for Vascular Regeneration Gene Therapy. [PDF]

open access: yesAnn Surg
Voza FA   +15 more
europepmc   +1 more source

Orexin B Reduces Cerebral Aneurysms Through Inhibition of SP‐1

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Orexin B/OX2R signaling attenuates cerebral aneurysm formation by suppressing SP‐1‐mediated inflammation, macrophage infiltration, and endothelial adhesion, with OX2R knockdown abolishing these protective effects. The study highlights Orexin B as a therapeutic candidate targeting vascular inflammation and remodeling in aneurysms.
Lei Chen   +4 more
wiley   +1 more source

Tacrolimus versus hydrocortisone in management of atopic dermatitis in children, a randomized controlled double-blind study: New insights on TARC, CTACK, TSLP, and E-selectin. [PDF]

open access: yesImmun Inflamm Dis
Binsaleh AY   +12 more
europepmc   +1 more source

Extracellular Vesicles as Drivers of Lung Endothelial Dysfunction in ARDS: Mechanisms and Therapeutic Opportunities

open access: yesComprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how extracellular vesicles from diverse pulmonary and extrapulmonary sources contribute to endothelial dysfunction in ARDS and evaluates emerging endothelial‐targeted therapies for their potential to mitigate EV‐mediated pathogenic mechanisms.
Mohammed Yaman Al Matni   +3 more
wiley   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

open access: yeseFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam   +4 more
wiley   +1 more source

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