Results 231 to 240 of about 131,570 (298)

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

The FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath, Subhoja Chakraborty, Sampa Biswas   +2 more
wiley   +1 more source

High-Yield Expression of Arylmalonate Decarboxylase in Escherichia coli Through High-Cell-Density Cultivation Strategies. [PDF]

Chembiochem
Gerstenberger J, Werbilo T, Kourist R, Kara S.   +3 more
europepmc   +1 more source

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

The FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu, Maximilian J. L. J. Fürst, Oscar P. Kuipers   +2 more
wiley   +1 more source

Application of NMRK immobilized enzymes in the synthesis of NMN. [PDF]

PLoS One
Yang S, Xiang T, Qian J, Sun W, Liu W, Yi N, Qin ZH.   +6 more
europepmc   +1 more source

Efficacy Assessment of Montanide GEL 02 PR and Liposome‐Based Encapsulation as Adjuvants for an FrpA Subunit Vaccine Against Photobacteriosis in Solea senegalensis

Journal of Fish Diseases, EarlyView.
ABSTRACT Photobacteriosis is a major threat to marine aquaculture, and the siderophore transporter FrpA represents a promising target for effective subunit vaccine development. In this study, we evaluated Montanide GEL 02 PR and phosphatidylcholine‐based liposomes as aqueous and safer alternatives to Freund's adjuvant for an FrpA‐based subunit vaccine ...
Marta A. Lages, Miguel Balado, Abel M. Forero, Lucía Ageitos, Jaime Rodríguez, Carlos Jiménez, Manuel L. Lemos, Beatriz Magariños   +7 more
wiley   +1 more source

Microgravity-induced constraints on melanin bioproduction: investigating E. coli metabolic responses aboard the international space station. [PDF]

NPJ Microgravity
Hennessa TM, VanArsdale ES, Leary D, Yang J, Davis RR, Barrila J, Schultzhaus Z, Romsdahl J, Smith AD, Scholes AN, Hervey J, Compton JR, Katilie CJ, Nickerson CA, Wang Z.   +14 more
europepmc   +1 more source

The GmGT‐2F, a trihelix transcription factor, regulates seed oil content by directly activating GmAGAL transcription in soybean

Journal of Integrative Plant Biology, EarlyView.
In soybean, the trihelix transcription factor GmGT‐2F positively regulates the expression of the α‐galactosidase gene GmAGAL, thereby modulating seed oil content. The cyclophilin GmCYP2 interacts with GmGT‐2F and suppresses GmAGAL activation. Haplotype diversity analysis of GmGT‐2F, GmCYP2, and GmAGAL identified favorable haplotype combinations ...
Shuangzhe Li, Yifan Cui, Yang Liu, Mingliang Yang, Xiaoxia Wu, Qingshan Chen, Ying Zhao   +6 more
wiley   +1 more source

Enhancing Caffeic Acid Production in Escherichia coli Through Heterologous Enzyme Combinations and Semi-Rational Design. [PDF]

Metabolites
Luo Q, Wang W, Huang Q, Wang C, Yan L, Kang J, Zhang J, Cheng J.   +7 more
europepmc   +1 more source

OsFKBP20‐1b stabilizes OsUPF1 and OsUPF2 to promote the degradation of aberrant mRNAs during dehydration stress

Journal of Integrative Plant Biology, EarlyView.
The rice protein OsFKBP20‐1b protects key RNA‐surveillance factors from breakdown, so they can better eliminate defective messages. This RNA quality‐control boost reduces errors and helps plants survive drought, revealing a link between RNA control and drought tolerance.
Haemyeong Jung, Hyun Ji Park, Seung Hee Jo, Ki‐Hong Jung, Choonkyun Jung, Hye Sun Cho   +5 more
wiley   +1 more source

lincRNA6679 promotes FnPR1B expression via phosphorylation‐activated FnWRKY14 to enhance strawberry resistance to Botrytis cinerea

Journal of Integrative Plant Biology, EarlyView.
In strawberry, Botrytis cinerea induces the expression of the long, intergenic non‐coding RNA lincRNA667，which upregulates the transcription factor gene FnWRKY14. FnWRKY14 then binds to the promoter of the pathogenesis‐related gene FnPR1B, enhancing strawberry resistance to B. cinerea.
Yuhan Guan, Zhuo Zhang, Zihui Zhang, Yan Wang, Wei Guo, Zhihong Zhang, He Li   +6 more
wiley   +1 more source