Results 241 to 250 of about 176,319 (351)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Preeclampsia (PE) is an obstetric disease that is characterized by reduced migration and invasion of placental trophoblast cells. Here, the effects of the E3 ubiquitin ligase UBE3A on the migration and invasion of trophoblast cells were evaluated.
Xiu‐Jun Li +5 more
wiley +1 more source
Deletion of the E3 ubiquitin ligase LRSAM1 fosters intracellular <i>Staphylococcus aureus</i> survival. [PDF]
Front Cell Infect MicrobiolPlöhn O +10 more
europepmc +1 more source
CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling
Med Research, EarlyView.CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li +8 more
wiley +1 more source
E3 ubiquitin ligase BTRC inhibits the proliferation and tumor growth of glioma cells through the NFAT5/AQP4 axis. [PDF]
J Cancer Res Clin OncolLi Y, Tang S, Jiang K, Deng P, Hu X.
europepmc +1 more source
Pink1 balances reticulophagy and mitophagy by regulating distinct E3 ubiquitin ligases [PDF]
Zhangyuan Yin, Daniel J. Klionsky
openalex +1 more source
LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease
Movement Disorders, EarlyView.Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang +12 more
wiley +1 more source
Genome-wide analysis of the RING-H2 E3 ubiquitin ligase SlATL family in tomato. [PDF]
Sci RepKong X +7 more
europepmc +1 more source