Results 101 to 110 of about 86,081 (238)

Unlocking Federated Learning for ESG Reporting: Prioritizing Critical Adoption Challenges in an Emerging Economy Context

Business Strategy and the Environment, EarlyView.
ABSTRACT The growing focus on environmental, social, and governance (ESG) issues has prompted organizations to explore innovative ways to manage their businesses. It has become imperative for organizations to adopt ESG reporting. The applications of federated learning help to enhance the scalability and credibility of ESG reporting in contemporary ...
Naveen Virmani, Srikant Gupta, Koppiahraj Karuppiah, Jose Arturo Garza‐Reyes   +3 more
wiley   +1 more source

Mechanism of HPV8-E7 mediated keratinocyte invasion [PDF]

, 2016
High-risk patient groups, such as immunosuppressed organ-transplant recipients and patients with the inherited skin disease Epidermodysplasia verruciformis, exhibit cancerisation of the skin, which are positive for human papillomaviruses (HPV) of the ...
Heuser, Sandra
core   +1 more source

New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines

Infectious Agents and Cancer
Background Development of immunotherapies and vaccines to treat HPV16-associated cancer requires reliable/effective small animal models. We developed such a model based on the murine mammary gland adenocarcinoma cells engineered to express HPV16 ...
Juris Jansons, Daria Avdoshina, Alesja Dudorova, Elena Royo Rubio, Liba Sokolovska, Dmitry Perminov, Ilze Lindenberga, Hannes Nicolai, Svetlana Gebrila, Sona Chowdhury, Dace Skrastina, Jurijs Nazarovs, Joel M. Palefsky, Maria Isaguliants   +13 more
doaj   +1 more source

RNA Interference of Human Papillomavirus Type 16 E7 Increases HLA Class I Antigen Expression in HaCaT-E7 Cells

, 2011
Background:High-risk human papillomaviruses (HPVs) are the major causative agents of cervical cancer. The E7 protein of high-risk HPV disturbs cell cycle control and down-regulates components of the antigen presentation pathway, suggesting an ideal ...
Li-Li Wang, Lu-Tao Du, Ni Zheng, Shun Wang, Gui-Xi Zheng, Xu-Hua Zhang, Zhao-Gang Dong, Xin Zhang, Wei Li, Xiao-Mei Deng, Xiao Zhang, Chuan-Xin Wang   +11 more
core   +1 more source

Dual‐Function Electrocatalysis: Simultaneous Wastewater Remediation and Hydrogen Evolution—A Comprehensive Review

Carbon Energy, EarlyView.
Replacing the oxygen evolution reaction with the electro‐oxidation of pollutants and waste streams offers an energy‐efficient route for simultaneous hydrogen production and pollutant remediation. This review summarizes the reaction mechanisms, catalyst design principles, and emerging paired‐electrolysis strategies that govern activity, selectivity ...
Safa Al‐Yahyaey, Rashid Al‐Hajri, Ala'a H. Al‐Muhtaseb, Hussein A. Younus, Mohammed Al‐Abri   +4 more
wiley   +1 more source

MmuPV1 E7 promotes phenotypes associated with “high-risk” HPV infection in mouse keratinocytes

Journal of Virology
The E7 oncoprotein of mouse papillomavirus (MmuPV1) plays a pivotal role in both viral infection and cancer development. While earlier studies have identified key cellular targets of MmuPV1 E7, such as pRB and PTPN14, the broader impact of MmuPV1 E7 on ...
Kayla R. Duxbury, Liyan Zhang, Laura K. Muelhbauer, Mitchell Hayes, Joshua J. Coon, Megha Padi, James C. Romero-Masters   +6 more
doaj   +1 more source

Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA

Virology Journal, 2007
Background Human papillomavirus (HPV) infection is known to be the most important etiologic factor of cervical cancer. There is no HPV specific therapy available for treatment of invasive squamous cell carcinoma of the cervix and its precursor lesions ...
Johansson Bo, Syrjänen Stina, Kari Ilkka, Peri Piritta, He Bin, Roizman Bernard, Hukkanen Veijo   +6 more
doaj   +1 more source

Bmi1 cooperates with E7 in cell immortalization.

, 2013
HFKs were doubly infected with pX-Bmi1 and pLXSN-E7, pLXSN-E7 alone, or empty vector. (A) Growth curve. Cells were passaged as described in the Methods section to determine the growth rate and lifespan of the cell populations.
Jonathan Miller (79680), Nancy Palechor-Ceron (399059), Richard Schlegel (4309), Aleksandra Dakic (399057), Bhaskar Kallakury (197766), Yuhai Dai (399060), Xuefeng Liu (130787), Renxiang Chen (399058)   +7 more
core   +1 more source

Supplier Environmental Assessment in Sustainability Reporting: Evidence From Top ESG‐Performing Brazilian Firms

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the maturity of supplier‐related environmental disclosures in sustainability reports of top environmental, social, and governance (ESG)‐performing Brazilian companies. A content analysis of 67 reports from firms listed on the Corporate Sustainability Index (CSI) was conducted using the CRITIC method to weight disclosure ...
João Vyctor Brás dos Santos, Tiago F. A. C. Sigahi, Deoclécio Junior Cardoso da Silva, Silvia Regina Stuchi Cruz, Milena Pavan Serafim, Walter Leal Filho, Rosley Anholon   +6 more
wiley   +1 more source

Monoclonal antibodies against human papillomavirus E7 oncoprotein for diagnosis of cervical neoplasia and cancer [PDF]

, 2012
Cervical cancer is the second most common cancer among women worldwide with half a million of new cases every year. Cervical cancer is caused by oncogenic human papillomaviruses (HPVs), with HPV16 and 18 being the most frequently detected types.
Lidqvist, Maria
core   +1 more source