Results 81 to 90 of about 57,660 (246)

New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines

Infectious Agents and Cancer
Background Development of immunotherapies and vaccines to treat HPV16-associated cancer requires reliable/effective small animal models. We developed such a model based on the murine mammary gland adenocarcinoma cells engineered to express HPV16 ...
Juris Jansons, Daria Avdoshina, Alesja Dudorova, Elena Royo Rubio, Liba Sokolovska, Dmitry Perminov, Ilze Lindenberga, Hannes Nicolai, Svetlana Gebrila, Sona Chowdhury, Dace Skrastina, Jurijs Nazarovs, Joel M. Palefsky, Maria Isaguliants   +13 more
doaj   +1 more source

Two Hundred Eighty Characters of Environment: Relative Environmental Performance, Strategic Communication, and Firm Value

Business Strategy and the Environment, EarlyView.
ABSTRACT Corporate environmental communication has become an essential aspect of modern business practices, as stakeholders increasingly demand transparency and accountability regarding sustainability efforts. Within this context, we examine whether firms use environmental communication on X/Twitter to offset weaker relative environmental performance ...
Ivan Russo, Federico Bertacchini, Ugo Rizzo, Maria Cristina Arcuri   +3 more
wiley   +1 more source

MmuPV1 E7 promotes phenotypes associated with “high-risk” HPV infection in mouse keratinocytes

Journal of Virology
The E7 oncoprotein of mouse papillomavirus (MmuPV1) plays a pivotal role in both viral infection and cancer development. While earlier studies have identified key cellular targets of MmuPV1 E7, such as pRB and PTPN14, the broader impact of MmuPV1 E7 on ...
Kayla R. Duxbury, Liyan Zhang, Laura K. Muelhbauer, Mitchell Hayes, Joshua J. Coon, Megha Padi, James C. Romero-Masters   +6 more
doaj   +1 more source

Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA

Virology Journal, 2007
Background Human papillomavirus (HPV) infection is known to be the most important etiologic factor of cervical cancer. There is no HPV specific therapy available for treatment of invasive squamous cell carcinoma of the cervix and its precursor lesions ...
Johansson Bo, Syrjänen Stina, Kari Ilkka, Peri Piritta, He Bin, Roizman Bernard, Hukkanen Veijo   +6 more
doaj   +1 more source

Gen‐AI Is Not an Option for Environment Sustainability‐Enabling of Gen‐AI for Responsible and Green Supply Chains Using a Grey Network Map (GNM)

Business Strategy and the Environment, EarlyView.
ABSTRACT Environmental sustainability in supply chains is no longer considered a compliance concern. It has become a strategic capability challenge, as firms seek to use Generative artificial intelligence (Gen‐AI) to improve decision quality, resource efficiency and responsible operations.
Anbesh Jamwal, Anil Kumar, Ashutosh Samadhiya, Sunil Luthra   +3 more
wiley   +1 more source

Prosumers and Sustainable Market Governance: Development of the Community‐Oriented Marketing Approach Scale

Business Strategy and the Environment, EarlyView.
ABSTRACT This research develops and empirically validates the Community‐Oriented Marketing Approach (COMA), a 20‐item multidimensional scale designed to measure prosumer perceptions within participatory market systems. COMA conceptualizes prosumers as active co‐value creators and institutional agents, driving sustainable market governance.
Alpaslan Kelleci, Oguzhan Essiz
wiley   +1 more source

HPV16 E7 modulates the cell surface expression of MET and CD109 via the AP2 complex

Tumour Virus Research
Multiple cellular pathways are affected by HPV E6 and E7 oncoproteins, including endocytic and cellular trafficking. HPV-16 E7 can target the adaptor protein (AP) complex, which contains proteins important during endocytosis transport.
Oscar Trejo-Cerro, Om Basukala, Michael P. Myers, Lawrence Banks   +3 more
doaj   +1 more source

Unlocking Circular Economy Potentials: Testing the Moderating and Mediating Roles of Cultural Diversity, Technological Innovation, and Digitalization

Business Strategy and the Environment, EarlyView.
ABSTRACT Green finance (GF) has emerged as a key policy instrument for advancing the circular economy (CE), yet its impact varies considerably across OECD countries. Existing research has not sufficiently examined how institutional, technological, and cultural contexts shape this relationship.
Mohammed Ibrahim Gariba, Solomon Gyamfi, Viktor Prokop, Jan Stejskal, Vikas Kumar, Cali Nuur   +5 more
wiley   +1 more source

A Strategy Cycle Nexus for Circular Economy and Industry 4.0 Integration: A Global Expert Perspective

Business Strategy and the Environment, EarlyView.
ABSTRACT The adoption of circular economy (CE) practices supported by Industry 4.0 (I4.0) technologies remains limited, despite their strong potential to enhance sustainable performance (SP). Organizations continue to face practical challenges in identifying effective strategies, enabling technologies, and implementation conditions.
Than'a Alsaoudi, Adolf Acquaye
wiley   +1 more source

Negative dimensions and E7 symmetry

Nuclear Physics B, 1981
Abstract The invariant length and volume which characterize the Lorentz group are extended to a quadratic and a quartic supersymmetric invariant. The symmetry group of the Grassmann sector can be SO(2), SU(2), SU(2) × SU(2) × SU(2), Sp(6), SU(6), SO(12) or E 7 , which are also possible global symmetries of extended supergravities.
openaire   +1 more source