HPV16-E7-Specific Activated CD8 T Cells in E7 Transgenic Skin and Skin Grafts [PDF]
Frontiers in Immunology, 2017 Human papillomavirus (HPV) 16 E7 (E7) protein expression in skin promotes epithelial hyperproliferation and transformation to malignancy. Grafts of murine skin expressing E7 protein as a transgene in keratinocytes are not rejected from immunocompetent ...
Seyed Davoud Jazayeri +3 more
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Self-Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines. [PDF]
Adv Sci (Weinh)Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Yang X +6 more
europepmc +2 more sources
Additional file 1 of MPS1 is involved in the HPV16-E7-mediated centrosomes amplification
, 2021 Additional file 1: Figure S1. E7 relative expression. E7 expression was calculated in control cells and U2OS-E7 transfected cells. We measure E7 expression values of cervical cancer cell lines reportedly with (SiHa) and without (c-33a) HPV16 integrated ...
José Díaz-Chávez (11651106) +7 more
core +1 more source
The E6E7 oncoproteins of cutaneous human papillomavirus type 38 interfere with the interferon pathway [PDF]
, 2008 Non-melanoma skin cancer is the most frequent malignancy in Caucasian populations. Evidence suggests the involvement of cutaneous Human Papillomavirus (HPV) of the genus beta () in this disease. The ability of E6 and E7 of mucosal HPV to promote cellular
Tommasino, M. +13 more
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Cell cycle control and its modulation in HPV infected cells [PDF]
, 2010 A key effect of human papillomavirus (HPV) infection is to disrupt the normal cell cycle in order to subvert the cellular DNA replication machinery. Morphologically, condylomata induced by high and low risk HPV types cannot be distinguished and many ...
Lyman, Rachel C.
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HPV-18 transformed cells fail to arrest in G1 in response to quercetin treatment [PDF]
, 2005 Previous work with primary human keratinocytes demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 with concomitant elevation of the cyclin-dependent kinase inhibitor (cdki ...
Beniston, R.G., Campo, M.S.
core +1 more source
, 2022 The major HPV oncogenes, E6 and E7, are known for its notoriety in driving the carcinogenic process in human papilloma virus (HPV) driven cancers. It is well-established that the removal of E7 dampens HPV cancer cell growth and proliferation.
Assis Ferreira, Danyelle +2 more
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Regulation of the Human Papillomavirus E7 Oncoprotein [PDF]
, 2023 HPV-induced carcinogenesis is mainly associated with the uncontrolled expression of the oncoproteins E6 and E7. HPV E7 lacks enzymatic activity, however, it can target several cellular proteins to induce cell transformation and promote unregulated ...
Trejo Cerro, Oscar
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The canine papillomavirus and gamma HPV E7 proteins use an alternative domain to bind and destabilize the retinoblastoma protein. [PDF]
PLoS Pathogens, 2010 The high-risk HPV E6 and E7 proteins cooperate to immortalize primary human cervical cells and the E7 protein can independently transform fibroblasts in vitro, primarily due to its ability to associate with and degrade the retinoblastoma tumor suppressor
Jingang Wang +4 more
doaj +1 more source
Toward a cognitive science of markets: economic agents as sense-makers
Economics: Journal Articles, 2019 Behavioral economics aspires to replace the agents of neoclassical economics with living, breathing human beings. Here, the author argues that behavioral economics, like its neoclassical counterpart, often neglects the role of active sense-making that ...
Johnson Samuel G.B.
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