Results 21 to 30 of about 57,660 (246)

Anti-Interleukin-6 Receptor Antibody Therapy-Induced Retinopathy in a Patient with Rheumatoid Arthritis

Case Reports in Rheumatology, 2012
Tocilizumab, a humanized anti-human interleukin-6 (IL-6) receptor monoclonal antibody, is beneficial for treating autoimmune conditions such as rheumatoid arthritis (RA).
Asumi Tada, Noriyasu Hashida, Toshio Tanaka, Kohji Nishida   +3 more
doaj   +1 more source

Distributed Storage Manager System for Synchronized and Scalable AV Services across Networks

International Journal of Digital Multimedia Broadcasting, 2011
This paper provides an innovative solution, namely, the distributed storage manager that opens a new path for highly interactive and personalized services.
Frank X. Sun, John Cosmas, Muhammad Ali Farmer, Abdul Waheed   +3 more
doaj   +1 more source

Economic modelling of residential energy communities, including thermal flexibilities: a business case for prosumers and grid operators?

International Journal of Sustainable Energy
The increasing decentralisation and volatility of electricity generation and consumption pose significant challenges for distribution grids. The concept of energy communities leveraging demand-side flexibility is emerging as a promising solution. However,
Guntram Pressmair, Alina Peischl, Sama Schoisengeier   +2 more
doaj   +1 more source

Identification and characterisation of novel potential phospho-acceptor sites in HPV-16 E7

Tumour Virus Research, 2023
Several studies have described functional regulation of high-risk human papillomaviruses (HPVs), E6 and E7 oncoproteins via posttranslational modifications (PTMs).
Oscar Trejo-Cerro, Justyna Broniarczyk, Nezka Kavcic, Michael Myers, Lawrence Banks   +4 more
doaj   +1 more source

The human papillomavirus E7 oncoprotein

Virology, 2009
The human papillomavirus (HPV) E7 oncoprotein shares functional similarities with such proteins as adenovirus E1A and SV40 large tumor antigen. As one of only two viral proteins always expressed in HPV-associated cancers, E7 plays a central role in both the viral life cycle and carcinogenic transformation.
McLaughlin-Drubin, Margaret E., Münger, Karl   +1 more
openaire   +2 more sources

New Water Oxidation Mechanism in Photosystem II Resolves Major Experimental Controversies

Angewandte Chemie, EarlyView.
In Photosystem II Oxygen Evolving Complex, we discovered the O3‐O6 peroxide at lower energy. Assignment of the O3 ligated by histidine (His337) as a slow exchanging substrate and its coupling with O6 give the O─O bond formation mechanism most consistent with all currently available experimental data. Proposal shows how protein environment can steer the
Yulia Pushkar
wiley   +2 more sources

MODERN ASPECTS OF HUMAN PAPILLOMAVIRUS VACCINATION

Безопасность и риск фармакотерапии, 2018
Human papillomavirus refers to DNA-containing viruses and infects the skin and mucosal epithelium. One common way is to change the  expression of cellular genes by integrating the viral genome into  cellular DNA.
O. S. Alyautdina, M. A. Darmostukova
doaj   +1 more source

Thermostable Bioluminescent Intercalating Dyes for Real‐Time, Integrated Nucleic Acid Amplification and Detection

Angewandte Chemie, EarlyView.
We present a bioluminescent diagnostic platform that integrates DNA amplification and detection in a single step. The engineering of thermostable luciferase‐intercalating dye conjugates and controlled release of caged luciferin substrates enable real‐time, detection of attomolar concentrations of viral DNA within 30 min.
Yosta de Stigter, Harmen J. van der Veer, Sterre de Lignie, Robbert J. de Haas, Renko de Vries, Joost P. H. Schoeber, Anne J. M. Loonen, Adriaan J. C. van den Brule, Maarten Merkx   +8 more
wiley   +2 more sources

Analysis of Energy Requirements for Massive Integration of Electric Buses in Ambato City, Ecuador

Engineering Proceedings
Ecuador’s Energy Efficiency Law mandates that “as of 2030, all vehicles incorporated into urban public transport services must be electric”. This legal framework sets the stage for the country’s transition to electric mobility. This research examines the
Paola Quintana, Angélica Vaca Yánez, Henry Acurio, Sebastián Villacrés, Verónica Guayanlema   +4 more
doaj   +1 more source

Full Vectorial Field Sensing Using Liquid Crystal Droplet Arrays

Advanced Materials, EarlyView.
An inkjet‐printed liquid crystal droplet array enables compact, low‐cost, single‐shot sensing of the full vectorial light field. Within a single platform, it simultaneously retrieves intensity, polarization, and phase, while dual‐wavelength operation highlights its capability for multi‐wavelength optical field characterization. ABSTRACT Determining the
Xuke Qiu, Jinge Guo, Jiahe Cui, Runchen Zhang, Zimo Zhao, Yifei Ma, Waqas Kamal, Steve J. Elston, Alfonso A. Castrejón‐pita, Stephen M. Morris, Chao He   +10 more
wiley   +1 more source