Results 21 to 30 of about 57,881 (149)

SOC1 inhibits HPV-E7-mediated transformation by inducing degradation of E7 protein [PDF]

Oncogene, 2004
Human papilloma viruses (HPVs) are small double-stranded DNA viruses that infect mucosal and cutaneous epithelium and induce cervical cancer. It has been shown that interferon (IFN)gamma suppresses proliferation of HPV-infected cells by suppressing expression of HPV E7.
Masaki Kamio, Takafumi Yoshida, Hisanobu Ogata, Tsutomu Douchi, Yukihiro Nagata, Makoto Inoue, Mamoru Hasegawa, Yoshikazu Yonemitsu, Akihiko Yoshimura   +8 more
openaire   +1 more source

Economic modelling of residential energy communities, including thermal flexibilities: a business case for prosumers and grid operators?

International Journal of Sustainable Energy
The increasing decentralisation and volatility of electricity generation and consumption pose significant challenges for distribution grids. The concept of energy communities leveraging demand-side flexibility is emerging as a promising solution. However,
Guntram Pressmair, Alina Peischl, Sama Schoisengeier   +2 more
doaj   +1 more source

Identification and characterisation of novel potential phospho-acceptor sites in HPV-16 E7

Tumour Virus Research, 2023
Several studies have described functional regulation of high-risk human papillomaviruses (HPVs), E6 and E7 oncoproteins via posttranslational modifications (PTMs).
Oscar Trejo-Cerro, Justyna Broniarczyk, Nezka Kavcic, Michael Myers, Lawrence Banks   +4 more
doaj   +1 more source

MODERN ASPECTS OF HUMAN PAPILLOMAVIRUS VACCINATION

Безопасность и риск фармакотерапии, 2018
Human papillomavirus refers to DNA-containing viruses and infects the skin and mucosal epithelium. One common way is to change the  expression of cellular genes by integrating the viral genome into  cellular DNA.
O. S. Alyautdina, M. A. Darmostukova
doaj   +1 more source

The human papillomavirus E7 oncoprotein

Virology, 2009
The human papillomavirus (HPV) E7 oncoprotein shares functional similarities with such proteins as adenovirus E1A and SV40 large tumor antigen. As one of only two viral proteins always expressed in HPV-associated cancers, E7 plays a central role in both the viral life cycle and carcinogenic transformation.
McLaughlin-Drubin, Margaret E., Münger, Karl   +1 more
openaire   +2 more sources

Analysis of Energy Requirements for Massive Integration of Electric Buses in Ambato City, Ecuador

Engineering Proceedings
Ecuador’s Energy Efficiency Law mandates that “as of 2030, all vehicles incorporated into urban public transport services must be electric”. This legal framework sets the stage for the country’s transition to electric mobility. This research examines the
Paola Quintana, Angélica Vaca Yánez, Henry Acurio, Sebastián Villacrés, Verónica Guayanlema   +4 more
doaj   +1 more source

Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine

Journal of Biomedical Science, 2021
Background Human Papillomavirus type 16 (HPV16) has been associated with a subset of head and neck cancers. Two HPV encoded oncogenic proteins, E6 and E7, are important for the malignant progression of HPV-associated cancers.
Ssu-Hsueh Tseng, Li Liu, Shiwen Peng, Jinhwi Kim, Louise Ferrall, Chien-Fu Hung, T. -C. Wu   +6 more
doaj   +1 more source

Distributed Storage Manager System for Synchronized and Scalable AV Services across Networks

International Journal of Digital Multimedia Broadcasting, 2011
This paper provides an innovative solution, namely, the distributed storage manager that opens a new path for highly interactive and personalized services.
Frank X. Sun, John Cosmas, Muhammad Ali Farmer, Abdul Waheed   +3 more
doaj   +1 more source

Effect of polyp regression and reduction on treatment efficacy in polypoidal choroidal vasculopathy treated with aflibercept

Scientific Reports
Intravitreal injection of aflibercept (IVA) has successfully treated polypoidal choroidal vasculopathy (PCV), and polyp morphology is an important indicator of treatment efficacy.
Kaori Sayanagi, Satoko Fujimoto, Chikako Hara, Yoko Fukushima, Kazuichi Maruyama, Ryo Kawasaki, Shigeru Sato, Kohji Nishida   +7 more
doaj   +1 more source

HPV-16 E7 Interacts with the Endocytic Machinery via the AP2 Adaptor μ2 Subunit

mBio, 2022
Human papillomavirus (HPV) E7 plays a major role in HPV-induced malignancy, perturbing cell cycle regulation, and driving cell proliferation. Major targets of cancer-causing HPV E7 proteins are the pRB family of tumor suppressors, which E7 targets for ...
Om Basukala, Oscar Trejo-Cerro, Michael P. Myers, David Pim, Paola Massimi, Miranda Thomas, Corrado Guarnaccia, David Owen, Lawrence Banks   +8 more
doaj   +1 more source