Results 21 to 30 of about 35,169 (184)
MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells. [PDF]
ImmunologyThis study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Si W, Zhu G, Jiang Q, Ma X, Yang G.
europepmc +2 more sources
NLRP3 Inflammasome and MS/EAE [PDF]
Autoimmune Diseases, 2013 Inflammasomes are cytosolic sensors that detect pathogens and danger signals in the innate immune system. The NLRP3 inflammasome is currently the most fully characterized inflammasome and is known to detect a wide array of microbes and endogenous damage-associated molecules.
Makoto Inoue, Mari L. Shinohara
openaire +2 more sources
Estudios sobre el Mensaje Periodístico, 2012 This work tries to analyze whether economic information in newspapers is perceived as a credible source for individuals to make their investment decisions considering two main aspects: they have little knowledge in this matter and they do not have many ...
José Ramón Sánchez-Galán
doaj +1 more source
Isolation and characterization of Shiga toxigenic Escherichia coli of animal and bird origin by multiplex polymerase chain reaction [PDF]
Veterinary World, 2016 Aim: The purpose of this study was to determine the virulence genes and serotype of Shiga toxin producing Escherichia coli (STEC) strains isolated from animals and birds.
S. Neher +5 more
doaj +1 more source
Cuadernos de Investigación Histórica, 2021 Las causas del desastre de Annual de 1921, se enraízan con la perdida de las últimas colonias españolas en América en 1898, y los problemas consecuentes para un ejercito anticuado, sobredimensionado en número de oficiales, con materiales obsoletos y ...
Emilio Sánchez de Rojas Díaz
doaj +1 more source
Qué hacer cuándo arde la red: gestión de crisis de comunicación on-line
La Revista Icono 14, 2021 RESEÑA Qué hacer cuándo arde la red: gestión de crisis de comunicación on-line José Manuel Burgueño UOC, Barcelona, 2018.
David López Jiménez
doaj +1 more source
Ingested (oral) SST inhibits EAE
Autoimmunity, 2011 Ingested immunoactive proteins type I interferon, soluble immune response suppressor peptide 1-21 and melanocyte-stimulating hormone inhibit clinical attacks and inflammation in acute experimental autoimmune encephalomyelitis (EAE).We examined whether another immunoactive protein, somatostatin (SST), would have similar anti-inflammatory effects on EAE ...
Staley A, Brod, Zachary M, Hood
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang +13 more
wiley +1 more source
BMC Research Notes, 2018 Objectives The aetiology of several human diarrhoeas has been increasingly associated with the presence of virulence factors rather than with the bacterial species hosting the virulence genes, exemplified by the sporadic emergence of new bacterial hosts.
Marc B. Anglès d’Auriac +1 more
doaj +1 more source
Advanced Science, EarlyView.Astrocytic TIA1‐mediated stress granules (SGs) promote demyelination by sequestering the mRNA of cholesterol synthesis genes. In this model, astrocytic TIA1‐mediated SGs were increased in the optic nerves of EAE mice, leading to the downregulation of cholesterol synthesis genes such as HMGCS1 through sequestration of their mRNA into SGs, which ...
Zheyu Fang +11 more
wiley +1 more source