Results 101 to 110 of about 434,910 (305)

The morphology of the inner ear of squamate reptiles and its bearing on the origin of snakes [PDF]

, 2017
The inner ear morphology of 80 snake and lizard species, representative of a range of ecologies, is here analysed and compared to that of the fossil stem snake Dinilysia patagonica, using three-dimensional geometric morphometrics. Inner ear morphology is
Caldwell, M., Hutchinson, M., Lee, M., Palci, A.   +3 more
core   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Flexibility within the middle ears of vertebrates [PDF]

, 2012
Introduction and aims: Tympanic middle ears have evolved multiple times independently among vertebrates, and share common features. We review flexibility within tympanic middle ears and consider its physiological and clinical implications.
Baird, Bell, Burda, Dahmann, Feenstra, Fleischer, Goode, Goode, Ingelstedt, Jørgensen, Kirikae, Kobrak, Larsen, Lenhardt, M J Mason, M R B Farr, Manley, Marquet, Mason, Mason, Mason, Mason, Mills, Narins, Nishihara, Pau, Rosowski, Schuknecht, Segall, Smith, Tideholm, Werner, Wever, Wever, Wever, Yamada, Özcan   +36 more
core   +1 more source

Next‐Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiological Monitoring

Advanced Science, EarlyView.
An analysis of literature trends and a historical overview of organic and inorganic piezoelectric materials, focusing on their structural diversity, functional mechanisms, and inherent characteristics. It then explores cutting‐edge developments in material synthesis, fabrication processes, and performance optimization, highlighting their applicability ...
Bangul Khan, Umay Amara, Bilawal Khan, Wasim Ullah Khan, Rafi u Shan Ahmad, Muhammad Shehzad Khan, Mohamed Elhousseini Hilal, Bee Luan Khoo   +7 more
wiley   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin Sam George, Anthony J. Ricci
wiley   +1 more source

Inner Ear Disease

, 2006
Publisher Summary It is now evident that the inner ear is not an “immunologically privileged” site and may mount an immune response against both foreign and self-antigens. This chapter focuses on sensorineural hearing loss (SNHL). This has been described and termed in different ways: autoimmune SNHL, immunemediated inner ear disease (IMIED ...
LUNARDI, Claudio, PUCCETTI, Antonio
openaire   +3 more sources

Inner ear development in cetaceans

Journal of Anatomy, 2016
AbstractCetaceans face the challenge of maintaining equilibrium underwater and obtaining sensory input within a dense, low‐visibility medium. The cetacean ear represents a key innovation that marked their evolution from terrestrial artiodactyls to among the most fully aquatic mammals in existence.
Thean, T, Kardjilov, N, Asher, RJ
openaire   +3 more sources

Comparative Cochlear Transcriptomics in Echolocating Bats and Mouse Reveals Hras as Protector Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen, Chenhao Che, Lingjie Wu, Changjie Sun, Dongming Xu, Qinyang Hua, Yunzhong Zhang, Yi‐Quan Tang, Peng Shi, Shan Sun   +9 more
wiley   +1 more source

Balance function after cochlear implant and inner ear anomaly: Comparison of dynamic posturography

Laryngoscope Investigative Otolaryngology, 2020
Introduction Patients with sensorineural hearing loss suffer concomitant vestibular dysfunction that is more prevalent in patients with inner ear anomaly and could be aggravated with cochlear implantation. To assess the vestibular dysfunction in patients
Farideh Hosseinzadeh, Alimohamad Asghari, Maziar Moradi‐Lakeh, Mohammad Farhadi, Ahmad Daneshi, Mohammad Mohseni, S.Saeed Mohammadi   +6 more
doaj   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source