Results 41 to 50 of about 3,779,020 (301)

Early Diagnosis of Hemoglobinopathies [PDF]

Pediatric Research, 1978
Summary: Antibodies specific for human hemoglobins F, A, S, and C were isolated by affinity chromatography from antisera produced in rabbits and goats. These reagents were shown to possess adequate sensitivity for identifying and quantifying hemoglobins A, S, and C in cord blood by radial immunodiffusion (RID).
V E, Headings, S I, Anyaibe, S P, Bhattacharya, E L, Hopkins   +3 more
openaire   +2 more sources

Diagnosis and management of iridocorneal endothelial syndrome [PDF]

, 2015
The iridocorneal endothelial (ICE) syndrome is a rare ocular disorder that includes a group of conditions characterized by structural and proliferative abnormalities of the corneal endothelium, the anterior chamber angle, and the iris.
Ambrosio, Oriella, Macchi, Ilaria, Mantelli, Flavio, Marenco, Marco, Rama, Paolo, SACCHETTI, MARTA   +5 more
core   +2 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Integrated transcriptomic and immunoinformatics analysis identifies tpx2, bub1b, and ube2c as diagnostic biomarkers and therapeutic targets in endometrial carcinoma

Discover Oncology
Objective This study aimed to identify novel diagnostic and prognostic biomarkers in endometrial carcinoma (EC) using integrative bioinformatics and immunohistochemical validation, with a focus on potential therapeutic targets and immune correlations ...
Shuyang Zhou, Jirui Sun, Jinmei Li, Xing Zhou, Xiaoyu Shi, Minghan Yang, Yanjing Wang, Jinku Zhang   +7 more
doaj   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia

Frontiers in Cell and Developmental Biology, 2022
Preeclampsia (PE) is a serious disease during pregnancy that affects approximately eight million mothers and infants worldwide each year and is closely related to abnormal trophoblast function.
Hao Wang, Hao Wang, Xiaowei Zhang, Xiaowei Zhang, Chunfeng Liu, Chunfeng Liu, Shengfu Chen, Xinyang Liu, Xinyang Liu, Shangrong Fan, Shangrong Fan   +10 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Efficacy and safety of lenvatinib plus pembrolizumab in patients with advanced and recurrent endometrial cancer: a systematic review and meta-analysis

Frontiers in Immunology
BackgroundVarious trials have demonstrated the clinical benefits of lenvatinib plus pembrolizumab in patients with advanced or recurrent endometrial cancer, regardless of mismatch repair (MMR) status or histologic subtype.
Guangwei Yan, Guangwei Yan, Yanmin Du, Yanmin Du, Huanhuan Zhang, Huanhuan Zhang, Jinxiang Yan, Jinxiang Yan, Yixuan Liu, Yixuan Liu, Zhenying Ban, Zhenying Ban, Yong-Zhen Guo, Yong-Zhen Guo, Xianxu Zeng, Xianxu Zeng   +15 more
doaj   +1 more source

Tumor-Infiltrating PD-1hiCD8+-T-Cell Signature as an Effective Biomarker for Immune Checkpoint Inhibitor Therapy Response Across Multiple Cancers

Frontiers in Oncology, 2021
BackgroundStratification of patients who could benefit from immune checkpoint inhibitor (ICI) therapy is of much importance. PD-1hiCD8+ T cells represent a newly identified and effective biomarker for ICI therapy response biomarker in lung cancer ...
Zhenyu Yang, Zhenyu Yang, Yulan Deng, Yulan Deng, Jiahan Cheng, Jiahan Cheng, Shiyou Wei, Shiyou Wei, Hao Luo, Hao Luo, Lunxu Liu, Lunxu Liu   +11 more
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source