Results 41 to 50 of about 1,763,176 (361)

Comparison of Aerosol Stability of Different Variants of Ebola Virus and Marburg Virus and Virulence of Aerosolised Ebola Virus in an Immune-Deficient Mouse

Viruses, 2022
During outbreaks of virus diseases, many variants may appear, some of which may be of concern. Stability in an aerosol of several Ebola virus and Marburg virus variants was investigated.
Sophie J. Smither, Lin S. Eastaugh, Mark S. Lever   +2 more
doaj   +1 more source

Rapid bedside inactivation of Ebola virus for safe nucleic acid tests [PDF]

, 2016
Rapid bedside inactivation of Ebola virus would be a solution for the safety of medical and technical staff, risk containment, sample transport and high-throughput or rapid diagnostic testing during an outbreak.
Bragstad, Karoline, Dudman, Susanne Gjeruldsen, Fomsgaard, Anders, Karlberg, Helen, Kran, Anne Marte Bakken, Lindegren, Gunnel, Mirazimi, Ali, Rosenstierne, Maiken Wors\uf8e, Salata, Cristiano, Stoltz, Malin Lundahl   +9 more
core   +1 more source

Innate Immunity to Ebola virus [PDF]

, 2023
Ebola virus is a negative sense RNA virus and belongs to the family of Filoviridae. It can cause severe disease including hemorrhagic fever and multiorgan failure.
Wildemann, Johanna
core   +1 more source

Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization. [PDF]

, 2017
BACKGROUND: The recent West African Ebola epidemic led to accelerated efforts to test Ebola vaccine candidates. As part of the World Health Organisation-led VSV Ebola Consortium (VEBCON), we performed a phase I clinical trial investigating rVSV-ZEBOV (a ...
Addo, MM, Becker, S, Biedenkopf, N, Borregaard, S, Dahlke, C, Eickmann, M, Fehling, SK, Jambrecina, A, Kasonta, R, Krähling, V, Lohse, AW, Lunemann, S, Ly, ML, Lütgehetmann, M, Olearo, F, Rechtien, A, Schmiedel, S, Spohn, M, Stahl, F, Strecker, T, Stubbe, HC, VEBCON Consortium, Zinser, ME   +22 more
core   +1 more source

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Nature, 2016
The most recent Ebola virus outbreak in West Africa, which was unprecedented in the number of cases and fatalities, geographic distribution, and number of nations affected, highlights the need for safe, effective, and readily available antiviral agents ...
Travis K Warren, R. Jordan, Michael K. Lo, A. Ray, R. Mackman, V. Soloveva, D. Siegel, M. Perron, R. Bannister, H. Hui, Nate Larson, R. Strickley, Jay B. Wells, Kelly S. Stuthman, Sean A. van Tongeren, N. Garza, G. Donnelly, A. Shurtleff, Cary J. Retterer, D. Gharaibeh, Rouzbeh Zamani, Tara A. Kenny, Brett Eaton, Elizabeth C. Grimes, Lisa S. Welch, L. Gomba, C. Wilhelmsen, D. Nichols, J. Nuss, Elyse R. Nagle, Jeffrey R. Kugelman, G. Palacios, Edward M. Doerffler, Sean Neville, Ernest A. Carra, M. Clarke, Lijun Zhang, W. Lew, B. Ross, Q. Wang, K. Chun, Lydia Wolfe, D. Babusis, Yeojin Park, Kirsten M. Stray, Iva Trancheva, Joy Y. Feng, O. Barauskas, Yili Xu, Pamela Wong, Molly R. Braun, M. Flint, L. McMullan, Shan-Shan Chen, R. Fearns, S. Swaminathan, D. Mayers, C. Spiropoulou, William A. Lee, S. Nichol, T. Cihlář, S. Bavari   +61 more
semanticscholar   +1 more source

Pre-Ebola virus disease laboratory system and related challenges in Liberia

African Journal of Laboratory Medicine, 2016
Prior to the Ebola virus disease outbreak in Liberia, the laboratory system was duplicativefragmented and minimally coordinated. The National Reference Laboratory was conceptualisedto address the existing challenges by promoting the implementation of ...
Stephen B. Kennedy, John B. Dogba, Christine L. Wasunna, Philip Sahr, Candace B. Eastman, Fatorma K. Bolay, Gloria T. Mason, Mark W.S. Kieh   +7 more
doaj   +1 more source

Increased Likelihood of Detecting Ebola Virus RNA in Semen by Using Sample Pelleting

Emerging Infectious Diseases, 2021
Ebola virus RNA can reside for months or years in semen of survivors of Ebola virus disease and is probably associated with increased risk for cryptic sexual transmission of the virus.
Courtney M. Bozman, Mosoka Fallah, Michael C. Sneller, Catherine Freeman, Lawrence S. Fakoli, Bode I. Shobayo, Bonnie Dighero-Kemp, Cavan S. Reilly, Jens H. Kuhn, Fatorma Bolay, Elizabeth Higgs, Lisa E. Hensley   +11 more
doaj   +1 more source

Exploiting the Reverse Vaccinology Approach to Design Novel Subunit Vaccine against Ebola Virus

medRxiv, 2020
Ebola virus is a highly pathogenic RNA virus that causes haemorrhagic fever in human. With very high mortality rate, Ebola virus is considered as one of the dangerous viruses in the world.
M. Ullah, Bishajit Sarkar, S. Islam
semanticscholar   +1 more source

Recommendations for dealing with waste contaminated with Ebola virus: a Hazard Analysis of Critical Control Points approach [PDF]

, 2016
Objective To assess, within communities experiencing Ebola virus outbreaks, the risks associated with the disposal of human waste and to generate recommendations for mitigating such risks.
Ahmed A Mohamedani, Benedict M Mutua, Brainard, Chepurnov, Diana J Bell, Edward Muchiri, Guy Howard, Harvey Minnigh, Iain Lake, Joseph Matofari, Julii Brainard, Julius M Ndambuki, Katherine Pond, Kelly L Edmunds, Lutendo S Mudau, Maggie Montgomery, Mark D Sobsey, Mark Zeitoun, Mike van der Es, Paul R Hunter, Peter Maes, Roger Few, Samir Dervisevic, Samira Abd Elrahman, Sarah Morter, Tsimbiri P Fedha   +25 more
core   +2 more sources

Involvement of Surfactant Protein D in Ebola Virus Infection Enhancement via Glycoprotein Interaction [PDF]

Viruses, MDPI, 2018, 11 (1), pp.15, 2019
Since the largest 2014-2016 Ebola virus disease outbreak in West Africa, understanding of Ebola virus infection has improved, notably the involvement of innate immune mediators. Amongst them, collectins are important players in the antiviral innate immune defense.
arxiv   +1 more source