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Exploiting the Reverse Vaccinology Approach to Design Novel Subunit Vaccine against Ebola Virus
medRxiv, 2020 Ebola virus is a highly pathogenic RNA virus that causes haemorrhagic fever in human. With very high mortality rate, Ebola virus is considered as one of the dangerous viruses in the world.
M. Ullah, Bishajit Sarkar, S. Islam
semanticscholar +1 more source
A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova +5 more
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Informatics in Medicine Unlocked, 2018 Ebola Virus Disease (EVD), is a national epidemic in Countries affected. It is also a potential global public health pandemic. The menace of the disease outbreak among West and Central African nations, in recent years, has resulted in the death of many ...
Olugbenga Oluwagbemi, Olaitan Awe
doaj +1 more source
Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir
Viruses, 2019 Remdesivir (GS-5734) is a 1′-cyano-substituted adenosine nucleotide analogue prodrug that shows broad-spectrum antiviral activity against several RNA viruses. This compound is currently under clinical development for the treatment of Ebola virus disease (
E. Tchesnokov +3 more
semanticscholar +1 more source
Numerical Simulation of the Fractal-Fractional Ebola Virus
Fractal and Fractional, 2020 In this work we present three new models of the fractal-fractional Ebola virus. We investigate the numerical solutions of the fractal-fractional Ebola virus in the sense of three different kernels based on the power law, the exponential decay and the ...
H. Srivastava, K. Saad
semanticscholar +1 more source
Projections of Ebola outbreak size and duration with and without vaccine use in Équateur, Democratic Republic of Congo, as of May 27, 2018. [PDF]
, 2018 As of May 27, 2018, 6 suspected, 13 probable and 35 confirmed cases of Ebola virus disease (EVD) had been reported in Équateur Province, Democratic Republic of Congo. We used reported case counts and time series from prior outbreaks to estimate the total
Ackley, Sarah +17 more
core +2 more sources
Mediterranean Journal of Infection Microbes and Antimicrobials, 2014 Ebola virus is one of the cause of viral hemorrhagic fever with high mortality rate. This recent West African outbreak is the largest Ebola outbreak in history. The current Ebola outbreak is caused by Zaire Ebola virus species. Ebola virus disease can be transmitted by direct contact with blood, body fluids and skin of infected patient and also person ...
Hakan Leblebicioğlu, İlkay Bozkurt
openaire +2 more sources
Ebola Virus Antibody Prevalence in Dogs and Human Risk
Emerging Infectious Diseases, 2005 During the 2001–2002 outbreak in Gabon, we observed that several dogs were highly exposed to Ebola virus by eating infected dead animals. To examine whether these animals became infected with Ebola virus, we sampled 439 dogs and screened them by Ebola ...
Loïs Allela +8 more
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A review of epidemiological parameters from Ebola outbreaks to inform early public health decision-making. [PDF]
, 2015 The unprecedented scale of the Ebola outbreak in West Africa has, as of 29 April 2015, resulted in more than 10,884 deaths among 26,277 cases. Prior to the ongoing outbreak, Ebola virus disease (EVD) caused relatively small outbreaks (maximum outbreak ...
Bento, AI +4 more
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Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda
PLoS Pathogens, 2008 Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case.
J. Towner +17 more
semanticscholar +1 more source