Results 131 to 140 of about 12,943 (270)

Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats [PDF]

, 2015
Biological factors that influence the host range and spillover of Ebola virus (EBOV) and other filoviruses remain enigmatic. While filoviruses infect diverse mammalian cell lines, we report that cells from African straw-colored fruit bats (Eidolon helvum)
Agnarsson, Allison, Almeida, Amman, Amman, Baker, Biesold, Bolger, Carette, Carroll, Carstea, Chandran, Cui, Côté, Daugherty, Deffieu, Delport, Demogines, Demogines, Drexler, Ebihara, Feldmann, Ge, Gire, Grabherr, He, Herbert, Hueffer, Jahrling, Jangra, Jayme, Jones, Kaelber, Kamins, Katzourakis, Krishnan, Kugelman, Kuhn, Kühl, Lee, Leroy, Li, Mali, Maruyama, Meyerson, Miller, Miller, Miller-Butterworth, Murrell, Negredo, Ng, Olival, Park, Parker, Paweska, Peel, Pond, Radoshitzky, Radoshitzky, Raj, Ren, Robertson, Ross, Runz, Ruxton, Sheahan, Swenson, Swenson, Takada, Taylor, Taylor, Taylor, Tong, Towner, Vanier, Volchkov, Wahl-Jensen, Wong, Yang   +78 more
core   +2 more sources

Fc‐FcγR interactions during infections: From neutralizing antibodies to antibody‐dependent enhancement

Immunological Reviews, Volume 328, Issue 1, Page 221-242, November 2024.
Summary Advances in antibody technologies have resulted in the development of potent antibody‐based therapeutics with proven clinical efficacy against infectious diseases. Several monoclonal antibodies (mAbs), mainly against viruses such as SARS‐CoV‐2, HIV‐1, Ebola virus, influenza virus, and hepatitis B virus, are currently undergoing clinical testing
Julia E. Edgar, Stylianos Bournazos
wiley   +1 more source

Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants [PDF]

, 2009
The NS3 protein of rice hoja blanca tenuivirus represents a viral suppressor of RNAi that sequesters small interfering (si)RNAs in vitro. To determine whether this siRNA binding property is the critical determinant for the suppressor activity of NS3, an ...
Goldbach, R.W., Hemmes, J.C., Kaaij, L., Lohuis, H., Prins, M.W., Schnettler, E.   +5 more
core   +2 more sources

Immunotherapeutics for Ebola Virus Disease: Hope on the Horizon

Biologics: Targets & Therapy, 2021
Kyle L O’Donnell, Andrea Marzi Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USACorrespondence: Andrea Marzi Email marzia@niaid.nih ...
O'Donnell KL, Marzi A
doaj  

Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies

Viruses, 2012
The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples ...
Gene G. Olinger, Ana Kuehne, Jennifer L. Audet, Kendra J. Alfson, Anthony Griffiths, Holly A. Bloomfield, Elizabeth E. Zumbrun, Ashley E. Keeney, Julia E. Biggins, Amy C. Shurtleff, Sina Bavari   +10 more
doaj   +1 more source

In vitro assembly of Ebola virus nucleocapsid-like complex expressed in E. coli [PDF]

, 2016
Ebola virus (EBOV) harbors an RNA genome encapsidated by nucleoprotein (NP) along with other viral proteins to form a nucleocapsid complex. Previous Cryo-eletron tomography and biochemical studies have shown the helical structure of EBOV nucleocapsid at ...
A Nanbo, AA Albertini, CL Hunt, CP Alvarez, D Bhella, DR Beniac, DW Leung, EH Egelman, EH Miller, F Iseni, F Yabukarski, GF Gao, H Wang, H Zhou, JA Mindell, JH Kuhn, JM White, K Maclellan, PJ Dziubanska, RG Tawar, RN Kirchdoerfer, RW Ruigrok, S Dong, S Watanabe, SJ Ludtke, T Noda, T Noda, T Noda, TA Bharat, TF Booth, TJ Green, TR Shaikh, X Gong, Y Huang   +33 more
core   +3 more sources

Renaming of genera Ebolavirus and Marburgvirus to Orthoebolavirus and Orthomarburgvirus, respectively, and introduction of binomial species names within family Filoviridae

Archives of Virology, 2023
Nadine Biedenkopf, A. Bukreyev, K. Chandran, Nicholas Di Paola, P. Formenty, Anthony Griffiths, A. Hume, E. Mühlberger, S. Netesov, Gustavo Palacios, J. Pawęska, S. Smither, A. Takada, Victoria Wahl, J. Kuhn   +14 more
semanticscholar   +1 more source

Suspected Ebolavirus Reservoir Species in Anthropogenic Landscapes

The Bulletin of the Ecological Society of America, Volume 106, Issue 2, April 2025.
Matthew LeBreton, Robert L. Cohen
wiley   +1 more source

Vaccine process technology—A decade of progress

Biotechnology and Bioengineering, Volume 121, Issue 9, Page 2604-2635, September 2024.
Abstract In the past decade, new approaches to the discovery and development of vaccines have transformed the field. Advances during the COVID‐19 pandemic allowed the production of billions of vaccine doses per year using novel platforms such as messenger RNA and viral vectors.
Barry Buckland, Gautam Sanyal, Todd Ranheim, David Pollard, Jim A. Searles, Sue Behrens, Stefanie Pluschkell, Jessica Josefsberg, Christopher J. Roberts   +8 more
wiley   +1 more source

Ebola virus VP35 interaction with dynein LC8 regulates viral RNA synthesis [PDF]

, 2015
Ebola virus VP35 inhibits alpha/beta interferon production and functions as a viral polymerase cofactor. Previously, the 8-kDa cytoplasmic dynein light chain (LC8) was demonstrated to interact with VP35, but the functional consequences were unclear. Here
Amarasinghe, Gaya K, Basler, Christopher F, Jordan, David S, Leung, Daisy W, Luthra, Priya   +4 more
core   +2 more sources