Results 131 to 140 of about 12,455 (266)

Computational and experimental identification of keystone interactions in Ebola virus matrix protein VP40 dimer formation

Protein Science, Volume 33, Issue 5, May 2024.
Abstract The Ebola virus (EBOV) is a lipid‐enveloped virus with a negative sense RNA genome that can cause severe and often fatal viral hemorrhagic fever. The assembly and budding of EBOV is regulated by the matrix protein, VP40, which is a peripheral protein that associates with anionic lipids at the inner leaflet of the plasma membrane.
Yogesh Narkhede, Roopashi Saxena, Tej Sharma, Jacob P. Conarty, Valentina Toro Ramirez, Balindile B. Motsa, Souad Amiar, Sheng Li, Prem P. Chapagain, Olaf Wiest, Robert V. Stahelin   +10 more
wiley   +1 more source

Ebolavirus:

Revista Gestão & Saúde, 2015
O atual surto de ebola tem devastado centenas de vidas, preocupando a comunidade cientifica devido à alta letalidade e difícil controle. Objetivamos observar quais os principais desafios para o controle do vírus e entender a importância de uma gestão ...
Rachid Figueirôa Souza, Aline Rafaela da Silva Rodrigues Machado, Julie Massayo Maeda Oda, Odanir Garcia Guerra, Alex Martins Machado   +4 more
doaj  

Seroprevalence of Ebola virus infection in Bombali District, Sierra Leone [PDF]

, 2017
A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of
Antonella Minutolo, Brima Kargbo, Carla Montesano, Ebola Study Group, Emmanuel Iwerima, Gianluca Russo, Marta Giovanetti, Massimo Amicosante, Mattei Maurizio, Nadege Goumkwa Mafopa, Patrick Turay, Raoul Emeric Guetiya Wadoum, Thomas B. Turay, Vincent Batwala   +13 more
core   +2 more sources

Cat–wildlife interactions and zoonotic disease risk: a call for more and better community science data

Mammal Review, Volume 54, Issue 2, Page 93-104, April 2024.
Domestic cats play a significant role in wildlife predation and they are likely involved in disease transmission. Abstract Due to their close interaction with both wildlife and humans, free‐ranging domestic animals are well‐suited to act as conveyors of zoonotic pathogens.
Tamara Szentivanyi, Malik Oedin, Ricardo Rocha   +2 more
wiley   +1 more source

Renaming of genera Ebolavirus and Marburgvirus to Orthoebolavirus and Orthomarburgvirus, respectively, and introduction of binomial species names within family Filoviridae

Archives of Virology, 2023
Nadine Biedenkopf, A. Bukreyev, K. Chandran, Nicholas Di Paola, P. Formenty, Anthony Griffiths, A. Hume, E. Mühlberger, S. Netesov, Gustavo Palacios, J. Pawęska, S. Smither, A. Takada, Victoria Wahl, J. Kuhn   +14 more
semanticscholar   +1 more source

Generalidades de la familia Filoviridae y el virus del Ébola: una actualización de sus implicaciones en la población humana

, 2020
Characteristics of the family Filoviridae and the Ebola virus: an update of its implications in the human population The family Filoviridae is integrated by a group of filamentous RNA viruses that cause severe hemorrhagic fevers in primates and other ...
Burgueño-Sosa, E., Esquivel Gómez, L., León-López, A., Rivadeneyra-Gutiérrez, E.   +3 more
core   +1 more source

Resource asynchrony and landscape homogenization as drivers of virulence evolution: The case of a directly transmitted disease in a social host

Ecology and Evolution, Volume 14, Issue 2, February 2024.
During disease outbreaks, pathogenic virulence is a key trait for successful spread. Global change comes with an increasing frequency of novel zoonotic diseases or disease outbreaks. Here, we use an individual‐based host–pathogen model to study how global change drivers affect virulence in a directly transmitted evolving pathogen in a social host.
Tobias Kürschner, Cédric Scherer, Viktoriia Radchuk, Niels Blaum, Stephanie Kramer‐Schadt   +4 more
wiley   +1 more source

Reston Ebolavirus Antibodies in Bats, the Philippines

Emerging Infectious Diseases, 2011
Reston Ebolavirus Antibodies in Bats, the PhilippinesPara el editor: Los filovirus causan fiebre hemorrágica altamente letal en humanos y primates no humanos, a excepción del Reston Ebolavirus (REBOV), que causa fiebre hemorrágica severa en macacos (1,2). Las epizootias de REBOV entre macacos cynomolgus ocurrieron en 1989, 1990, 1992 y 1996 (2) y entre
Hikaru Fujii, Shigeru Kyuwa, Joseph S. Masangkay, Naoya Ueda, Yoshiyuki Ishii, Phillip A. Alviola, Satoshi Taniguchi, Satoshi Taniguchi, Shigeru Morikawa, Yasuhiro Yoshikawa, Tetsuya Mizutani, Koichiro Iha, Koichiro Iha, Tsutomu Omatsu, Masayuki Saijo, Shumpei Watanabe, Shumpei Watanabe, Ichiro Kurane, Shuetsu Fukushi, Tetsuro Ikegami, Hiroomi Akashi   +20 more
openaire   +3 more sources

Bioengineered small extracellular vesicles deliver multiple SARS‐CoV‐2 antigenic fragments and drive a broad immunological response

Journal of Extracellular Vesicles, Volume 13, Issue 2, February 2024.
Abstract The COVID‐19 pandemic highlighted the clear risk that zoonotic viruses pose to global health and economies. The scientific community responded by developing several efficacious vaccines which were expedited by the global need for vaccines. The emergence of SARS‐CoV‐2 breakthrough infections highlights the need for additional vaccine modalities
Hannah K. Jackson, Heather M. Long, Juan Carlos Yam‐Puc, Roberta Palmulli, Tracey A. Haigh, Pehuén Pereyra Gerber, Jin S. Lee, Nicholas J. Matheson, Lesley Young, John Trowsdale, Mathew Lo, Graham S. Taylor, James E. Thaventhiran, James R. Edgar   +13 more
wiley   +1 more source

RIG-I activation inhibits ebolavirus replication

Virology, 2009
Hemorrhagic fever viruses are associated with rapidly progressing severe disease with high case fatality, making them of public health and biothreat importance. Effective antivirals are not available for most of the members of this diverse group of viruses. A broad spectrum strategy for antiviral development would be very advantageous. Perhaps the most
Thomas G. Ksiazek, Takashi Fujita, Stuart T. Nichol, Christina F. Spiropoulou, Suryaprakash Sambhara, Pierre E. Rollin, Shivaprakash Gangappa, César G. Albariño, Melissa B. Pearce, Priya Ranjan, Tara K. Sealy   +10 more
openaire   +3 more sources