Results 151 to 160 of about 12,455 (266)

Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop

Cell Reports, 2018
Summary: Monoclonal antibodies (mAbs) with pan-ebolavirus cross-reactivity are highly desirable, but development of such mAbs is limited by a lack of a molecular understanding of cross-reactive epitopes.
Charles D. Murin, Jessica F. Bruhn, Zachary A. Bornholdt, Jeffrey Copps, Robyn Stanfield, Andrew B. Ward   +5 more
doaj  

Clinical prognostic factors determining the survival of patients with the Ebola virus

Revista Cubana de Medicina Militar, 2020
Introduction: Ebola virus disease has a high lethality, which is why it is of great interest to carry out research that addresses clinical manifestations that could be prognostic factors for survival.
Osvaldo Miranda Gómez, Carlos Manuel Castro Baras, Yoel Alberto Fleites Alonso, José Eduardo Díaz Gómez, Yanetsi Contreras Olive, Sara Anneris Urgellés Carrera   +5 more
doaj   +2 more sources

Ebolavirus: preparados ou não?

Revista Eletronica Gestão & Saúde, 2015
O atual surto de ebola tem devastado centenas de vidas, preocupando a comunidade cientifica devido à alta letalidade e difícil controle. Objetivamos observar quais os principais desafios para o controle do vírus e entender a importância de uma gestão prévia para diminuir a propagação da doença, visando precaver um possível surto.
Odanir Garcia Guerra, Julie Massayo Maeda Oda, Alex Martins Machado, Rachid Figueirôa Souza, Aline Rafaela da Silva Rodrigues Machado   +4 more
openaire   +2 more sources

Secreted Glycoprotein from Live Zaire ebolavirus—Infected Cultures: Preparation, Structural and Biophysical Characterization, and Thermodynamic Stability [PDF]

, 2007
Laura G. Barrientos, Amy Martin, Robert M. Wohlhueter, Pierre E. Rollin   +3 more
openalex   +1 more source

Modular Polymerase Synthesis and Internal Protein Domain Swapping via Dual Opposed Frameshifts in the Ebola Virus L Gene

Pathogens
Sequence analysis of the Zaire ebolavirus (EBOV) polymerase (L gene) mRNA, using online tools, identified a highly ranked −1 programmed ribosomal frameshift (FS) signal including an ideal slippery sequence heptamer (UUUAAAA), with an overlapping coding ...
David B. Stubbs, Jan A. Ruzicka, Ethan W. Taylor   +2 more
doaj   +1 more source

Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Zaire ebolavirus, Sudan ebolavirus, Marburg and Lassa viruses

bioRxiv, 2023
A. Flaxman, Sarah Sebastian, Sofia Appelberg, Kuan M Cha, M. Ulaszewska, Jyothi N. Purushotham, Ciarán Gilbride, Hannah Sharpe, Alexandra J. Spencer, S. Bibi, Daniel Wright, S. Dowall, L. Easterbrook, Stephen Findlay-Wilson, Sarah C. Gilbert, A. Mirazimi, T. Lambe   +16 more
semanticscholar   +1 more source

The Tyro3 Receptor Kinase Axl Enhances Macropinocytosis of Zaire Ebolavirus [PDF]

, 2010
Catherine L. Hunt, Andrey A. Kolokoltsov, Robert A. Davey, Wendy Maury   +3 more
openalex   +1 more source

Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes

Cell Reports, 2023
E. Chen, P. Gilchuk, Seth J. Zost, Philipp A. Ilinykh, E. Binshtein, Kai Huang, Luke Myers, Stefano Bonissone, Samuel B. Day, Chandrahaas R. Kona, Andrew Trivette, Joseph X. Reidy, Rachel E. Sutton, Christopher Gainza, S. Diaz, Jazmean K. Williams, Christopher N Selverian, E. Davidson, E. Saphire, B. Doranz, N. Castellana, A. Bukreyev, R. Carnahan, James E. Crowe   +23 more
semanticscholar   +1 more source

Rapid Sequence Identification of Potential Pathogens Using Techniques from Sparse Linear Algebra

, 2015
The decreasing costs and increasing speed and accuracy of DNA sample collection, preparation, and sequencing has rapidly produced an enormous volume of genetic data. However, fast and accurate analysis of the samples remains a bottleneck. Here we present
Chiu, Nelson, Dodson, Stephanie, Kepner, Jeremy, Ricke, Darrell O., Shcherbina, Anna   +4 more
core   +1 more source

Structure and Function of the Fusion Loop from Ebolavirus GP2 [PDF]

, 2011
Sonia M. Gregory, E. Harada, Binyong Liang, Sue E. Delos, Judith M. White, Lukas K. Tamm   +5 more
openalex   +1 more source