Results 51 to 60 of about 12,455 (266)

Epidemiology of Ebolaviruses from an Etiological Perspective

open access: yesPathogens, 2023
Since the inception of the ebolavirus in 1976, 32 outbreaks have resulted in nearly 15,350 deaths in more than ten countries of the African continent. In the last decade, the largest (2013–2016) and second largest (2018–2020) ebolavirus outbreaks have ...
Sahil Jain   +4 more
doaj   +1 more source

Ebolavirus: Infection, Vaccination and Control [PDF]

open access: bronzeMolecular Genetics, Microbiology and Virology, 2021
Members of the genus Ebolavirus (family Filoviridae) are among the deadliest viral pathogens spread throughout the world with severe rate of mortality, at least 90% in some outbreaks. Their virions are filamentous and enveloped with enclosed negative-sense single-stranded RNA genome.
Abdul Ahad   +4 more
openalex   +2 more sources

Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway

open access: yesAutophagy, 2022
Zaire ebolavirus (EBOV) causes a severe hemorrhagic fever in humans and non-human primates with high morbidity and mortality. EBOV infection is dependent on its structural glycoprotein (GP), but high levels of GP expression also trigger cell rounding ...
Bin Wang   +10 more
semanticscholar   +1 more source

Ebolavirus: Pseudotypes, Libraries and Standards [PDF]

open access: yesFuture Virology, 2015
Globalization, accompanied by increasing levels of international travel and trade, climate change, altered human behavior and demographics, is leading to the emergence of manifold viral diseases, many of which are highly pathogenic and hence are considered of great public and animal health importance to the global populace [1].
Nigel J. Temperton, Mark Page
openaire   +3 more sources

Flow cytometry evaluation of the rhesus monkey cellular immunity following the Zaire ebolavirus (Filoviridae; Ebolavirus: Zaire ebolavirus) experimental infection

open access: yesProblems of Virology, 2021
Introduction. The outbreaks of the Zaire ebolavirus (ZE) disease (ZED) that have arisen in the last decade determine the need to study the infection pathogenesis, the formation of specific immunity forming as well as the development of effective preventive and therapeutic means.
G. V. Borisevich   +15 more
openaire   +5 more sources

Ebolavirus Evolution: Past and Present

open access: yesPLOS Pathogens, 2015
The past year has marked the most devastating Ebola outbreak the world has ever witnessed, with over 28,000 cases and over 11,000 deaths. Ebola virus (EBOV) has now been around for almost 50 years. In this review, we discuss past and present outbreaks of EBOV and how those variants evolved over time.
Derek R. Stein   +4 more
openaire   +7 more sources

RNF185 regulates proteostasis in Ebolavirus infection by crosstalk between the calnexin cycle, ERAD, and reticulophagy

open access: yesNature Communications, 2022
Virus infection affects cellular proteostasis and provides an opportunity to study this cellular process under perturbation. The proteostasis network in the endoplasmic reticulum (ER) is composed of the calnexin cycle, and the two protein degradation ...
J. Zhang   +7 more
semanticscholar   +1 more source

Data from: A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection [PDF]

open access: yes, 2017
The dataset contains findings and information from 51 seroprevelance studies performed from on samples collected from 1961 to 2016. These investigated 84 exposure-defined subgroups of subjects reported to have had no symptoms of EVD during the outbreak ...
Bower, Hilary, Glynn, Judith
core   +2 more sources

Tenacious Researchers Identify a Weakness in All Ebolaviruses. [PDF]

open access: yes, 2018
The Ebolavirus genus has at least five members, four of which are known to cause deadly disease in humans. An ideal therapy or a vaccine would protect against all ebolaviruses, but identifying a common weakness in all of them has remained elusive.
DuBois, Rebecca M
core   +1 more source

Ebola virus disease (EVD) outbreak re-emergence regulation in East Africa: preparedness and vaccination perspective [PDF]

open access: yes, 2023
Sudan ebolavirus (SUDV), Bundibugyo ebolavirus, Taï Forest ebolavirus, and Zaire ebolavirus (EBOV) are the most potentially life-threatening and grievous species reported among the Ebolavirus genus.
Bora, Jutishna   +8 more
core   +1 more source

Home - About - Disclaimer - Privacy