Results 51 to 60 of about 11,522 (197)

Ebolavirus and Haemorrhagic Syndrome

Sultan Qaboos University Medical Journal, 2015
The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world's most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in up to 90% of patients.
Gerald A. Matua, Dirk M. Van der Wal, Rozzano C. Locsin   +2 more
openaire   +4 more sources

Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors

mAbs, 2020
Ebola virus (EBOV) can cause severe hemorrhagic fever in humans, and no approved treatment is currently available. Although several antibodies have achieved good protection in animal models, the potential emerging isolates of ebolavirus and the unknown ...
Pengfei Fan, Xiangyang Chi, Guodong Liu, Guanying Zhang, Zhengshan Chen, Yujiao Liu, Ting Fang, Jianmin Li, Logan Banadyga, Shihua He, Changming Yu, Xiangguo Qiu, Wei Chen   +12 more
doaj   +1 more source

Ebolavirus diagnosis made simple, comparable and faster than molecular detection methods: preparing for the future

Virology Journal, 2018
Background The 2014/2015 Ebolavirus outbreak resulted in more than 28,000 cases and 11,323 reported deaths, as of March 2016. Domestic transmission of the Guinea strain associated with the outbreak occurred mainly in six African countries, and ...
Ameh S. James, Shawn Todd, Nina M. Pollak, Glenn A. Marsh, Joanne Macdonald   +4 more
doaj   +1 more source

Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats [PDF]

, 2015
Biological factors that influence the host range and spillover of Ebola virus (EBOV) and other filoviruses remain enigmatic. While filoviruses infect diverse mammalian cell lines, we report that cells from African straw-colored fruit bats (Eidolon helvum)
Agnarsson, Allison, Almeida, Amman, Amman, Baker, Biesold, Bolger, Carette, Carroll, Carstea, Chandran, Cui, Côté, Daugherty, Deffieu, Delport, Demogines, Demogines, Drexler, Ebihara, Feldmann, Ge, Gire, Grabherr, He, Herbert, Hueffer, Jahrling, Jangra, Jayme, Jones, Kaelber, Kamins, Katzourakis, Krishnan, Kugelman, Kuhn, Kühl, Lee, Leroy, Li, Mali, Maruyama, Meyerson, Miller, Miller, Miller-Butterworth, Murrell, Negredo, Ng, Olival, Park, Parker, Paweska, Peel, Pond, Radoshitzky, Radoshitzky, Raj, Ren, Robertson, Ross, Runz, Ruxton, Sheahan, Swenson, Swenson, Takada, Taylor, Taylor, Taylor, Tong, Towner, Vanier, Volchkov, Wahl-Jensen, Wong, Yang   +78 more
core   +2 more sources

The Molecular Genetic Peculiarities of Genomic Structure of Members of the Ebolavirus Genus

Проблемы особо опасных инфекций, 2015
The molecular genetic peculiarities of genomic structure of the Ebolavirus genus members are viewed in the review. The Ebola virus disease outbreaks in West African countries constitute a threat not only for Africa, but for the whole world in view of ...
A. A. Petrov, V. N. Lebedev, L. F. Stovba, T. E. Sizikova, T. M. Plekhanova, O. N. Sidorova, N. S. Pyshnaya, D. I. Paveliev, S. V. Borisevich   +8 more
doaj   +1 more source

[Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations].

Voprosy virusologii, 2021
Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the largest of which escalated into an epidemic in 2014-2016 and caused the death of more than 11,000 people.
I. V. Dolzhikova, D. N. Shcherbinin, D. Yu. Logunov, A. L. Gintsburg   +3 more
openaire   +2 more sources

Assessment of healthcare worker protocol deviations and self-contamination during personal protective equipment donning and doffing [PDF]

, 2017
OBJECTIVETo evaluate healthcare worker (HCW) risk of self-contamination when donning and doffing personal protective equipment (PPE) using fluorescence and MS2 bacteriophage.DESIGNProspective pilot study.SETTINGTertiary-care hospital.PARTICIPANTSA total ...
Burnham, Carey-Ann D, Cass, Candice, Dubberke, Erik R, Fraser, Victoria J, Hink, Tiffany, Kwon, Jennie H, Liang, Stephen Y, Reske, Kimberly A, Seiler, Sondra, Shupe, Angela, Wallace, Meghan A   +10 more
core   +2 more sources

Ebolavirus Classification Based on Natural Vectors [PDF]

DNA and Cell Biology, 2015
According to the WHO, ebolaviruses have resulted in 8818 human deaths in West Africa as of January 2015. To better understand the evolutionary relationship of the ebolaviruses and infer virulence from the relationship, we applied the alignment-free natural vector method to classify the newest ebolaviruses.
Hui, Zheng, Changchuan, Yin, Tung, Hoang, Rong Lucy, He, Jie, Yang, Stephen S-T, Yau   +5 more
openaire   +2 more sources

Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda.

PLoS Pathogens, 2008
Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case.
Jonathan S Towner, Tara K Sealy, Marina L Khristova, César G Albariño, Sean Conlan, Serena A Reeder, Phenix-Lan Quan, W Ian Lipkin, Robert Downing, Jordan W Tappero, Samuel Okware, Julius Lutwama, Barnabas Bakamutumaho, John Kayiwa, James A Comer, Pierre E Rollin, Thomas G Ksiazek, Stuart T Nichol   +17 more
doaj   +1 more source

Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma

Frontiers in Immunology, 2021
Three clinically relevant ebolaviruses – Ebola (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) viruses, are responsible for severe disease and occasional deadly outbreaks in Africa.
Pavlo Gilchuk, Adrian Guthals, Stefano R. Bonissone, Jared B. Shaw, Philipp A. Ilinykh, Philipp A. Ilinykh, Kai Huang, Kai Huang, Robin G. Bombardi, Jenny Liang, Ariadna Grinyo, Edgar Davidson, Elaine C. Chen, Bronwyn M. Gunn, Galit Alter, Erica Ollmann Saphire, Benjamin J. Doranz, Alexander Bukreyev, Alexander Bukreyev, Alexander Bukreyev, Larry Zeitlin, Natalie Castellana, James E. Crowe, James E. Crowe, James E. Crowe   +24 more
doaj   +1 more source