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Epidemiology of Ebolaviruses from an Etiological Perspective
Since the inception of the ebolavirus in 1976, 32 outbreaks have resulted in nearly 15,350 deaths in more than ten countries of the African continent. In the last decade, the largest (2013–2016) and second largest (2018–2020) ebolavirus outbreaks have ...
Sahil Jain+4 more
doaj +1 more source
Ebolavirus: Infection, Vaccination and Control [PDF]
Members of the genus Ebolavirus (family Filoviridae) are among the deadliest viral pathogens spread throughout the world with severe rate of mortality, at least 90% in some outbreaks. Their virions are filamentous and enveloped with enclosed negative-sense single-stranded RNA genome.
Abdul Ahad+4 more
openalex +2 more sources
Zaire ebolavirus (EBOV) causes a severe hemorrhagic fever in humans and non-human primates with high morbidity and mortality. EBOV infection is dependent on its structural glycoprotein (GP), but high levels of GP expression also trigger cell rounding ...
Bin Wang+10 more
semanticscholar +1 more source
Ebolavirus: Pseudotypes, Libraries and Standards [PDF]
Globalization, accompanied by increasing levels of international travel and trade, climate change, altered human behavior and demographics, is leading to the emergence of manifold viral diseases, many of which are highly pathogenic and hence are considered of great public and animal health importance to the global populace [1].
Nigel J. Temperton, Mark Page
openaire +3 more sources
Introduction. The outbreaks of the Zaire ebolavirus (ZE) disease (ZED) that have arisen in the last decade determine the need to study the infection pathogenesis, the formation of specific immunity forming as well as the development of effective preventive and therapeutic means.
G. V. Borisevich+15 more
openaire +5 more sources
Ebolavirus Evolution: Past and Present
The past year has marked the most devastating Ebola outbreak the world has ever witnessed, with over 28,000 cases and over 11,000 deaths. Ebola virus (EBOV) has now been around for almost 50 years. In this review, we discuss past and present outbreaks of EBOV and how those variants evolved over time.
Derek R. Stein+4 more
openaire +7 more sources
Virus infection affects cellular proteostasis and provides an opportunity to study this cellular process under perturbation. The proteostasis network in the endoplasmic reticulum (ER) is composed of the calnexin cycle, and the two protein degradation ...
J. Zhang+7 more
semanticscholar +1 more source
Data from: A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection [PDF]
The dataset contains findings and information from 51 seroprevelance studies performed from on samples collected from 1961 to 2016. These investigated 84 exposure-defined subgroups of subjects reported to have had no symptoms of EVD during the outbreak ...
Bower, Hilary, Glynn, Judith
core +2 more sources
Tenacious Researchers Identify a Weakness in All Ebolaviruses. [PDF]
The Ebolavirus genus has at least five members, four of which are known to cause deadly disease in humans. An ideal therapy or a vaccine would protect against all ebolaviruses, but identifying a common weakness in all of them has remained elusive.
DuBois, Rebecca M
core +1 more source
Ebola virus disease (EVD) outbreak re-emergence regulation in East Africa: preparedness and vaccination perspective [PDF]
Sudan ebolavirus (SUDV), Bundibugyo ebolavirus, Taï Forest ebolavirus, and Zaire ebolavirus (EBOV) are the most potentially life-threatening and grievous species reported among the Ebolavirus genus.
Bora, Jutishna+8 more
core +1 more source