Background The 2014/2015 Ebolavirus outbreak resulted in more than 28,000 cases and 11,323 reported deaths, as of March 2016. Domestic transmission of the Guinea strain associated with the outbreak occurred mainly in six African countries, and ...
Ameh S. James +4 more
doaj +1 more source
Ebola Haemorrhagic Fever in Africa: a Necessary Highlight [PDF]
The purpose of this commentary is to re-evaluate the historic and scientific facts on Ebola haemorrhagic fever and the role of the International community, especially Economic Community of West African States (ECOWAS) in stemming the tide.
Adu-Gyamfi, S. (Samuel)
core +3 more sources
Introducing EbolaCheck: potential for point-of-need infectious disease diagnosis [PDF]
The 2013–2015 Ebolavirus disease humanitarian crisis has spurred the development of laboratory-free, point-of-care nucleic acid testing solutions.
Christie A +6 more
core +1 more source
The Molecular Genetic Peculiarities of Genomic Structure of Members of the Ebolavirus Genus
The molecular genetic peculiarities of genomic structure of the Ebolavirus genus members are viewed in the review. The Ebola virus disease outbreaks in West African countries constitute a threat not only for Africa, but for the whole world in view of ...
A. A. Petrov +8 more
doaj +1 more source
[Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations].
Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the largest of which escalated into an epidemic in 2014-2016 and caused the death of more than 11,000 people.
I. V. Dolzhikova +3 more
openaire +2 more sources
The face of Ebola: changing frequency of haemorrhage in the West African compared with Eastern-Central African outbreaks [PDF]
BACKGROUND: The West-African (WA) Zaire Ebolavirus disease (EVD) outbreak was characterized by an exceptionally high number of cases and deaths as compared with the Eastern-Central African (ECA) outbreaks.
Crispian Scully +4 more
core +4 more sources
Ebolavirus Classification Based on Natural Vectors [PDF]
According to the WHO, ebolaviruses have resulted in 8818 human deaths in West Africa as of January 2015. To better understand the evolutionary relationship of the ebolaviruses and infer virulence from the relationship, we applied the alignment-free natural vector method to classify the newest ebolaviruses.
Hui, Zheng +5 more
openaire +2 more sources
Summary: Monoclonal antibodies (mAbs) with pan-ebolavirus cross-reactivity are highly desirable, but development of such mAbs is limited by a lack of a molecular understanding of cross-reactive epitopes.
Charles D. Murin +5 more
doaj +1 more source
Assessment of healthcare worker protocol deviations and self-contamination during personal protective equipment donning and doffing [PDF]
OBJECTIVETo evaluate healthcare worker (HCW) risk of self-contamination when donning and doffing personal protective equipment (PPE) using fluorescence and MS2 bacteriophage.DESIGNProspective pilot study.SETTINGTertiary-care hospital.PARTICIPANTSA total ...
Burnham, Carey-Ann D +10 more
core +2 more sources
Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein [PDF]
Ebolaviruses cause severe disease in humans, and identification of monoclonal antibodies (mAbs) that are effective against multiple ebolaviruses are important for therapeutics development. Here we describe a distinct class of broadly neutralizing human mAbs with protective capacity against three ebolaviruses infectious for humans: Ebola (EBOV), Sudan ...
Gilchuk, Pavlo +31 more
openaire +4 more sources

