Results 51 to 60 of about 12,924 (266)
Epidemiology of Ebolaviruses from an Etiological Perspective
Pathogens, 2023 Since the inception of the ebolavirus in 1976, 32 outbreaks have resulted in nearly 15,350 deaths in more than ten countries of the African continent. In the last decade, the largest (2013–2016) and second largest (2018–2020) ebolavirus outbreaks have ...
Sahil Jain +4 more
doaj +1 more source
Natural history of Sudan ebolavirus infection in rhesus and cynomolgus macaques
Emerging Microbes and Infections, 2022 Due to its high mortality rate and continued re-emergence, Ebolavirus disease (EVD) continues to pose a serious threat to global health. A group of viruses within the genus Ebolavirus causes this severe hemorrhagic disease in humans: Ebola virus (EBOV ...
Courtney Woolsey +10 more
semanticscholar +1 more source
Autophagy, 2022 Zaire ebolavirus (EBOV) causes a severe hemorrhagic fever in humans and non-human primates with high morbidity and mortality. EBOV infection is dependent on its structural glycoprotein (GP), but high levels of GP expression also trigger cell rounding ...
Bin Wang +10 more
semanticscholar +1 more source
Ebolavirus: Pseudotypes, Libraries and Standards [PDF]
Future Virology, 2015 Globalization, accompanied by increasing levels of international travel and trade, climate change, altered human behavior and demographics, is leading to the emergence of manifold viral diseases, many of which are highly pathogenic and hence are considered of great public and animal health importance to the global populace [1].
Nigel J. Temperton, Mark Page
openaire +3 more sources
Ebolavirus vaccines for humans and apes [PDF]
Current Opinion in Virology, 2012 Because of high case fatality proportions, person-to-person transmission, and potential use in bioterrorism, the development of a vaccine against ebolavirus remains a top priority. Although no licensed vaccine or treatment against ebolavirus is currently available, progress in preclinical testing of countermeasures has been made.
Hugues Fausther-Bovendo +2 more
openaire +3 more sources
Ebolavirus Evolution: Past and Present
PLOS Pathogens, 2015 The past year has marked the most devastating Ebola outbreak the world has ever witnessed, with over 28,000 cases and over 11,000 deaths. Ebola virus (EBOV) has now been around for almost 50 years. In this review, we discuss past and present outbreaks of EBOV and how those variants evolved over time.
Derek R. Stein +4 more
openaire +7 more sources
Problems of Virology, 2021 Introduction. The outbreaks of the Zaire ebolavirus (ZE) disease (ZED) that have arisen in the last decade determine the need to study the infection pathogenesis, the formation of specific immunity forming as well as the development of effective preventive and therapeutic means.
G. V. Borisevich +15 more
openaire +5 more sources
Data from: A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection [PDF]
, 2017 The dataset contains findings and information from 51 seroprevelance studies performed from on samples collected from 1961 to 2016. These investigated 84 exposure-defined subgroups of subjects reported to have had no symptoms of EVD during the outbreak ...
Bower, Hilary, Glynn, Judith
core +2 more sources
Vaccines, 2023 (1) Background and Purpose: Ebola virus (EBOV) is the causative agent of Ebola virus disease (EVD), which causes extremely high mortality and widespread epidemics.
Junqi Zhang +17 more
semanticscholar +1 more source
Ebolavirus and Marburgvirus: Insight the Filoviridae family [PDF]
Molecular Aspects of Medicine, 2008 Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins. No significant homology is observed between filovirus proteins and any known macromolecule.
P. Ascenzi +7 more
openaire +9 more sources