Results 81 to 90 of about 1,365 (152)

Data_Sheet_4_Herd Immunity to Ebolaviruses Is Not a Realistic Target for Current Vaccination Strategies.PDF

open access: yes, 2018
The recent West African Ebola virus pandemic, which affected >28,000 individuals increased interest in anti-Ebolavirus vaccination programs. Here, we systematically analyzed the requirements for a prophylactic vaccination program based on the basic ...
Mark N. Wass (614017)   +4 more
core   +1 more source

Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. [PDF]

open access: yes, 2018
Ebolaviruses cause severe disease in humans, and identification of monoclonal antibodies (mAbs) that are effective against multiple ebolaviruses are important for therapeutics development.
Flinko, Robin   +31 more
core   +1 more source

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

open access: yesNature Communications, 2019
Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV).
Jennifer M. Brannan   +18 more
doaj   +1 more source

Immune Memory to Sudan Virus: Comparison between Two Separate Disease Outbreaks

open access: yesViruses, 2015
Recovery from ebolavirus infection in humans is associated with the development of both cell-mediated and humoral immune responses. According to recent studies, individuals that did not survive infection with ebolaviruses appear to have lacked a robust ...
Ariel Sobarzo   +14 more
doaj   +1 more source

Accounting for population structure reveals ambiguity in the Zaire Ebolavirus reservoir dynamics.

open access: yesPLoS Neglected Tropical Diseases, 2020
Ebolaviruses pose a substantial threat to wildlife populations and to public health in Africa. Evolutionary analyses of virus genome sequences can contribute significantly to elucidate the origin of new outbreaks, which can help guide surveillance ...
Bram Vrancken   +13 more
doaj   +1 more source

Data_Sheet_5_Herd Immunity to Ebolaviruses Is Not a Realistic Target for Current Vaccination Strategies.PDF

open access: yes, 2018
The recent West African Ebola virus pandemic, which affected >28,000 individuals increased interest in anti-Ebolavirus vaccination programs. Here, we systematically analyzed the requirements for a prophylactic vaccination program based on the basic ...
Mark N. Wass (614017)   +4 more
core   +1 more source

Analysis of the humoral immune responses among cynomolgus macaque naturally infected with Reston virus during the 1996 outbreak in the Philippines

open access: yesBMC Veterinary Research, 2012
Background Ebolaviruses induce lethal viral hemorrhagic fevers (VHFs) in humans and non-human primates, with the exceptions of Reston virus (RESTV), which is not pathogenic for humans.
Taniguchi Satoshi   +14 more
doaj   +1 more source

Data_Sheet_3_Herd Immunity to Ebolaviruses Is Not a Realistic Target for Current Vaccination Strategies.PDF

open access: yes, 2018
The recent West African Ebola virus pandemic, which affected >28,000 individuals increased interest in anti-Ebolavirus vaccination programs. Here, we systematically analyzed the requirements for a prophylactic vaccination program based on the basic ...
Mark N. Wass (614017)   +4 more
core   +1 more source

Aerosol Transmission of Filoviruses

open access: yesViruses, 2016
Filoviruses have become a worldwide public health concern because of their potential for introductions into non-endemic countries through international travel and the international transport of infected animals or animal products.
Berhanu Mekibib, Kevin K. Ariën
doaj   +1 more source

An exploration of conditions proposed to trigger the Ebola virus glycoprotein for fusion.

open access: yesPLoS ONE, 2019
Ebolaviruses continue to inflict horrific disease and instill fear. The 2013-2016 outbreak in Western Africa caused unfathomable morbidity and mortality (over 11,000 deaths), and the second largest outbreak is on-going in the Democratic Republic of the ...
Lucie Fénéant   +3 more
doaj   +1 more source

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