Results 81 to 90 of about 1,365 (152)
The recent West African Ebola virus pandemic, which affected >28,000 individuals increased interest in anti-Ebolavirus vaccination programs. Here, we systematically analyzed the requirements for a prophylactic vaccination program based on the basic ...
Mark N. Wass (614017) +4 more
core +1 more source
Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. [PDF]
Ebolaviruses cause severe disease in humans, and identification of monoclonal antibodies (mAbs) that are effective against multiple ebolaviruses are important for therapeutics development.
Flinko, Robin +31 more
core +1 more source
Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates
Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV).
Jennifer M. Brannan +18 more
doaj +1 more source
Immune Memory to Sudan Virus: Comparison between Two Separate Disease Outbreaks
Recovery from ebolavirus infection in humans is associated with the development of both cell-mediated and humoral immune responses. According to recent studies, individuals that did not survive infection with ebolaviruses appear to have lacked a robust ...
Ariel Sobarzo +14 more
doaj +1 more source
Accounting for population structure reveals ambiguity in the Zaire Ebolavirus reservoir dynamics.
Ebolaviruses pose a substantial threat to wildlife populations and to public health in Africa. Evolutionary analyses of virus genome sequences can contribute significantly to elucidate the origin of new outbreaks, which can help guide surveillance ...
Bram Vrancken +13 more
doaj +1 more source
The recent West African Ebola virus pandemic, which affected >28,000 individuals increased interest in anti-Ebolavirus vaccination programs. Here, we systematically analyzed the requirements for a prophylactic vaccination program based on the basic ...
Mark N. Wass (614017) +4 more
core +1 more source
Background Ebolaviruses induce lethal viral hemorrhagic fevers (VHFs) in humans and non-human primates, with the exceptions of Reston virus (RESTV), which is not pathogenic for humans.
Taniguchi Satoshi +14 more
doaj +1 more source
The recent West African Ebola virus pandemic, which affected >28,000 individuals increased interest in anti-Ebolavirus vaccination programs. Here, we systematically analyzed the requirements for a prophylactic vaccination program based on the basic ...
Mark N. Wass (614017) +4 more
core +1 more source
Aerosol Transmission of Filoviruses
Filoviruses have become a worldwide public health concern because of their potential for introductions into non-endemic countries through international travel and the international transport of infected animals or animal products.
Berhanu Mekibib, Kevin K. Ariën
doaj +1 more source
An exploration of conditions proposed to trigger the Ebola virus glycoprotein for fusion.
Ebolaviruses continue to inflict horrific disease and instill fear. The 2013-2016 outbreak in Western Africa caused unfathomable morbidity and mortality (over 11,000 deaths), and the second largest outbreak is on-going in the Democratic Republic of the ...
Lucie Fénéant +3 more
doaj +1 more source

