Results 31 to 40 of about 28,261 (176)
PLoS Pathogens, 2021 Ebola virus (EBOV) expresses three different glycoproteins (GPs) from its GP gene. The primary product, soluble GP (sGP), is secreted in abundance during infection. EBOV sGP has been discussed as a potential pathogenicity factor, however, little is known
Wakako Furuyama +3 more
doaj +1 more source
Viruses, 2016 The 2014 outbreak of Ebola virus (EBOV) in Western Africa highlighted the need for anti-EBOV therapeutics. Clomiphene is a U.S. Food and Drug Administration (FDA)-approved drug that blocks EBOV entry and infection in cells and significantly protects EBOV-
Elizabeth A. Nelson +5 more
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Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.This review summarises the detection methods for severe fever with thrombocytopenia syndrome virus based on CRISPR platforms. (A) CRISPR with fluorescent reporter. (B) CRISPR with lateral flow test strip. (C) CRISPR with DNAzyme. (D) Digital CRISPR. (E) CRISPR with single micro‐ring resonator biosensor. (F) self‐amplifying signal amplification strategy
Junhu Wang +8 more
wiley +1 more source
Engineered Human Cathelicidin Antimicrobial Peptides Inhibit Ebola Virus Infection
iScience, 2020 Summary: The 2014–2016 West Africa Ebola virus (EBOV) outbreak coupled with the most recent outbreaks in Central Africa underscore the need to develop effective treatment strategies against EBOV.
Yangsheng Yu +13 more
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VIEW, Volume 7, Issue 5, October 2026.2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu +11 more
wiley +1 more source
Sequence optimized diagnostic assay for Ebola virus detection
Scientific Reports, 2023 Rapid pathogen identification is a critical first step in patient isolation, treatment, and controlling an outbreak. Real-time PCR is a highly sensitive and specific approach commonly used for infectious disease diagnostics.
Jeffrey W. Koehler +8 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Drying in Blood Reduces Viability of EBOV/Yam-May More Than EBOV/Mak-C05.
, 2016 Drops of human whole blood (10 μL) spiked with either EBOV/Mak-C05 (blue) or EBOV/Yam-May (red) were spotted onto surface coupons. The spots were either recovered immediately (pre-dry) or dried at (A) 22°C/41% RH for one hour, or (B) 28°C/90% RH for four
Artemas Herzog (2155816) +9 more
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Anti-EBOV GP IgGs lacking alpha 1-3-galactose and neu5Gc prolong survival and decrease blood viral load in EBOV-Infected guinea pigs [PDF]
, 2016 Polyclonal xenogenic IgGs, although having been used in the prevention and cure of severe infectious diseases, are highly immunogenic, which may restrict their usage in new applications such as Ebola hemorrhagic fever.
Hélène Perreault (2825738) +67 more
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Impact of cell passaging on EBOV infection.
, 2018 Vero E6 (A) and Huh 7 (B) cells were passaged and infected with EBOV/Mak at an MOI of 1 at 48 hpi, the plates were fixed, stained, and the percentage of EBOV-positive cells was determined by HCI. Each point is the mean of 3 replicate wells and represents
Nicole Deiuliis (4994453) +17 more
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