Results 121 to 130 of about 218,916 (388)

Serum cytokine profiling differentiates underlying diseases in cytokine storm syndrome

Arthritis &Rheumatology, Accepted Article.
Objective Cytokine storm syndrome (CSS), commonly associated with hemophagocytic lymphohistiocytosis (HLH), is a fatal hyperinflammatory syndrome. Differentiating the underlying diseases responsible for CSS is essential for timely therapeutic decisions. This study explored the clinical usefulness of serum cytokine profiling in distinguishing underlying
Shuya Kaneko, Maho Hatano, Asami Shimbo, Futaba Miyaoka, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Mao Mizuta, Yasuo Nakagishi, Keiji Akamine, Naomi Iwata, Kenji Furuno, Takayuki Tanaka, Kazuyuki Ueno, Shuhei Fujita, Koji Yokoyama, Toshinori Minato, Kazushi Izawa, Takahiro Yasumi, Tadashi Matsubayashi, Tadashi Hosoya, Hiroki Nishikawa, Junya Fujimura, Ryoko Asano, Yuko Sugita, Kenichi Watanabe, Anna Kobayashi, Takuya Endo, Katsuhide Eguchi, Ryuta Nishikomori, Ryuhei Yasuoka, Takaki Asano, Miyako Kanno, Kazuya Hamada, Yuji Fujita, Daisuke Hayashi, Shojiro Watanabe, Takeshi Shiba, Shinsuke Yasuda, Masaaki Mori, Hirokazu Kanegane, Masatoshi Takagi, Masaki Shimizu   +42 more
wiley   +1 more source

Serodiagnosis of infectious mononucleosis by using recombinant Epstein-Barr virus antigens and enzyme-linked immunosorbent assay technology [PDF]

, 1990
Four recombinant, diagnostically useful Epstein-Barr virus (EBV) proteins representative of the viral capsid antigen (p150), diffuse early antigen (p54), the major DNA-binding protein (p138), and the EBV nuclear antigen (p72) (W. Hinderer, H.
Gorgievski-Hrisoho, M., Hinderer, W., Horn, J., Nebel-Schickel, H., Siegl, G., Sonneborn, H. H., Vornhagen, R., Wolf, Hans J.   +7 more
core   +1 more source

Complexities associated with expression of Epstein-Barr virus (EBV) lytic origins of DNA replication. [PDF]

, 2007
EBV has two lytic origins (oriLyt) of DNA replication lying at divergent sites on the viral genome within a duplicated sequence (DS). The latter contains potential hairpin loops, ‘hinge’ elements and the promoters for transcripts from viral genes BHLF1 ...
Griffin, BE, Xue, SA
core   +2 more sources

EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

OncoTarget, 2014
PD-L1 expression is a feature of Epstein-Barr virus (EBV) associated malignancies such as nasopharyngeal carcinoma (NPC). Here, we found that EBV-induced latent membrane protein 1 (LMP1) and IFN-γ pathways cooperate to regulate programmed cell death ...
W. Fang, Jianwei Zhang, Shaodong Hong, J. Zhan, N. Chen, T. Qin, Yanna Tang, Yaxiong Zhang, Shiyang Kang, Ting Zhou, Xuan Wu, W. Liang, Zhihuang Hu, Yuxiang Ma, Yuanyuan Zhao, Ying Tian, Yunpeng Yang, C. Xue, Yue Yan, X. Hou, Pei-yu Huang, Yan Huang, Hongyun Zhao, Li Zhang   +23 more
semanticscholar   +1 more source

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

Cancer Communications, EarlyView.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li, Jianyuan Zhou, Shuang Wang, Qian Yang, Shulun Nie, Chunwang Ji, Xue Zhang, Shuhan Li, Xuanyu Zhou, Jiahui Chu, Xuehui Wu, Jianqiao Jiao, Ruitao Xu, Qian Xu, Miao Huang, Qiushi Wang, Liliang Dou, Qinqin Hu, Fan Jiang, Xin Dai, Zhaodi Nan, Xinyu Song, Di Zhang, Lian Liu   +23 more
wiley   +1 more source

The oral mucosal and salivary microbial community of Behçet's syndrome and recurrent aphthous stomatitis. [PDF]

, 2015
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is ...
Bankvall M, Bruce Paster, Farida Fortune, Francis Drobniewski, International study group for Behcet's disease, Lesley A. Bergmeier, Noha Seoudi, Soderling E, Sun JB, Toiviainen A   +9 more
core   +3 more sources

EBV-miR-BART10-3p facilitates epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRC

OncoTarget, 2015
Epstein-Barr virus (EBV) infection is closely associated with tumorigenesis and development of nasopharyngeal carcinoma (NPC), but the underlying molecular mechanisms remain poorly understood.
Qijia Yan, Zhaoyang Zeng, Zhaojian Gong, Wenling Zhang, Xiayu Li, Baoyu He, Yali Song, Qiao Li, Yong Zeng, Q. Liao, Pan Chen, Lei Shi, S. Fan, Bo Xiang, Jian Ma, Ming Zhou, Xiaoling Li, Jianbo Yang, W. Xiong, Gui-yuan Li   +19 more
semanticscholar   +1 more source

Profiling of EBV-Encoded microRNAs in EBV-Associated Hemophagocytic Lymphohistiocytosis

The Tohoku Journal of Experimental Medicine, 2015
Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) is a life-threatening complication of EBV infection. MicroRNAs (miRNAs) were small non-coding RNA, and EBV could encode miRNAs that are involved in the progression of infection. However, the profiles of EBV-miRNAs in EBV-HLH were unknown. Here, we aimed to profile the expression
Li Zhang, Junhong Ai, Chunyan Liu, Chen Zhou, Li-Wei Gao, Kunling Shen, Zhengde Xie   +6 more
openaire   +4 more sources

Accurate and Efficient Detection of Nasopharyngeal Carcinoma Using Multi‐Dimensional Features of Plasma Cell‐Free DNA

Head &Neck, EarlyView.
ABSTRACT Background The incidence of Nasopharyngeal carcinoma (NPC) is rising in recent years, especially in some non‐developed parts of the world. Hence, cost‐efficient means for sensitive detection of NPC are vital. Methods We recruited 646 participants, including healthy individuals, patients with benign nasopharyngeal diseases, and NPC patients for
Song Zhang, Jiahui Tang, Pin Cui, Weihuang He, Xiaohui Lin, Shubing Wang, Yuanxian Liu, Xiaohua Tan, Shu Xu, Mingji Feng, Hanming Lai   +10 more
wiley   +1 more source

Sarcopenia Trajectories Predict Survival in Operable Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Sarcopenia is associated with increased treatment toxicity and survival in head and neck squamous cell cancer (HNSCC). This study evaluates sarcopenia trajectories and their association with overall survival (OS) and disease‐free survival (DFS) in operable HNSCC.
Marco A. Mascarella, Alex Mlynarek, Keith Richardson, Karen Kost, Anthony Zeitouni, Khalil Sultanem, Christina Tsien, George Shenouda, Nathaniel Bouganim, Khashayar Esfahani, Michael Hier, Nader Sadeghi, Marie‐Jeanne Kergoat   +12 more
wiley   +1 more source