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Progress in EBV Vaccines [PDF]
The Epstein-Barr virus (EBV) is a ubiquitous pathogen that imparts a significant burden of disease on the human population. EBV is the primary cause of infectious mononucleosis and is etiologically linked to the development of numerous malignancies.
Dwain G. van Zyl +7 more
openaire +5 more sources
Gene Therapy for Pediatric Cancer: State of the Art and Future Perspectives [PDF]
While modern treatments have led to a dramatic improvement in survival for pediatric malignancy, toxicities are high and a significant proportion of patients remain resistant.
Biagi, Ettore +3 more
core +5 more sources
Epstein–Barr virus (EBV) infects up to 95% of the adult human population, with primary infection typically occurring during childhood and usually asymptomatic. However, EBV can cause infectious mononucleosis in approximately 35–50% cases when infection occurs during adolescence and early adulthood.
Pagano, Joseph S. +2 more
openaire +3 more sources
The role of viral infection in bronchial asthma (BA) is well-known being reflected particularly in GINA. An effect of pneumotropic intracellular persistent herpesviruses on the course of BA is of particular interest. The most common viruses of this group
Evgeniy N. Suprun +5 more
doaj +1 more source
EBV expresses a number of viral noncoding RNAs (ncRNAs) during latent infection, many of which have known regulatory functions and can post-transcriptionally regulate viral and/or cellular gene expression. With recent advances in RNA sequencing technologies, the list of identified EBV ncRNAs continues to grow.
Rebecca L, Skalsky, Bryan R, Cullen
openaire +2 more sources
The Modulation of Apoptotic Pathways by Gammaherpesviruses
Apoptosis or programmed cell death is a tightly regulated process fundamental for cellular development and elimination of damaged or infected cells during the maintenance of cellular homeostasis. It is also an important cellular defense mechanism against
Shuvomoy eBanerjee +4 more
doaj +1 more source
Posttransplant lymphoproliferative disorders in neuronal xenotransplanted macaques [PDF]
Posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of lymphoid proliferations that occur in the setting of depressed T-cell function due to immunosuppressive therapy used following solid organ transplantation, hematopoietic ...
Aron Badin, R. +12 more
core +1 more source
Early-life infections with persistent Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are delayed in affluent countries, probably due to alterations in early environmental exposures, such as maternal age, siblings and day care attendance.
Claudia Carvalho-Queiroz +10 more
doaj +1 more source
Helicobacter pylori and Epstein-Barr virus infection in gastric diseases: Correlation with IL-10 and IL1RN polymorphism. [PDF]
Introduction: Helicobacter pylori and Epstein-Barr virus (EBV) infection have recently 23 been shown to be associated with gastric diseases. Polymorphisms in genes encoding 24 cytokines such as interleukin 10 (IL-10) and interleukin 1 Receptor (IL-1RN ...
Anna Giammanco +11 more
core +1 more source
Assessing the fitness of Epstein-Barr virus following its reactivation
Epstein-Barr virus (EBV) is usually maintained latently on passaging in cell culture, as are most herpesviruses in vivo. Its fitness, or its ability to infect and replicate in naïve cells, cannot be ascertained by serially passaging it in host cells ...
Yen-Fu Adam Chen +6 more
doaj +1 more source

