Steroid Control of Longevity in Drosophila melanogaster [PDF]
, 2003 Ecdysone, the major steroid hormone of Drosophila melanogaster, is known for its role in development and reproduction. Flies that are heterozygous for mutations of the ecdysone receptor exhibit increases in life-span and resistance to various stresses ...
Benzer, Seymour +3 more
core +1 more source
The role of cytochrome c in caspase activation in Drosophila melanogaster cells [PDF]
, 2002 The release of cytochrome c from mitochondria is necessary for the formation of the Apaf-1 apoptosome and subsequent activation of caspase-9 in mammalian cells.
Cakouros, Dimitrios +5 more
core +3 more sources
Ecdysteroids: A novel class of anabolic agents? [PDF]
, 2015 Increasing numbers of dietary supplements with ecdysteroids are marketed as “natural anabolic agents”. Results of recent studies suggested that their anabolic effect is mediated by estrogen receptor (ER) binding. Within this study the anabolic potency of
BOTRE', Francesco +5 more
core +2 more sources
Bab2 Functions as an Ecdysone-Responsive Transcriptional Repressor during Drosophila Development
Cell Reports, 2020 Summary: Drosophila development is governed by distinct ecdysone steroid pulses that initiate spatially and temporally defined gene expression programs. The translation of these signals into tissue-specific responses is crucial for metamorphosis, but the
Jianli Duan +7 more
doaj +1 more source
Mechanisms regulating nutrition-dependent developmental plasticity through organ-specific effects in insects [PDF]
, 2013 Nutrition, via the insulin/insulin-like growth factor (IIS)/Target of Rapamycin (TOR) signaling pathway, can provide a strong molding force for determining animal size and shape.
Koyama, Takashi +2 more
core +2 more sources
Increased insulin/insulin growth factor signaling advances the onset of metamorphosis in Drosophila. [PDF]
PLoS ONE, 2009 Mechanisms by which attainment of specific body sizes trigger developmental transitions to adulthood (e.g. puberty or metamorphosis) are incompletely understood.
Magdalena A Walkiewicz, Michael Stern
doaj +1 more source
Juvenile hormone regulates body size and perturbs insulin signaling in Drosophila [PDF]
, 2014 The role of juvenile hormone (JH) in regulating the timing and nature of insect molts is well-established. Increasing evidence suggests that JH is also involved in regulating final insect size.
Gokhale, R. H. +8 more
core +1 more source
Effects of contaminants of emerging concern on Megaselia scalaris (Lowe, Diptera: Phoridae) and its microbial community. [PDF]
, 2017 Drought, rising temperatures, and expanding human populations are increasing water demands. Many countries are extending potable water supplies by irrigating crops with wastewater.
Gan, Jay +5 more
core +1 more source
Nature Communications, 2021 Pupariation in Drosophila is triggered by the steroid-hormone ecdysone and requires coordination between associated behavioral and body-reshaping motor subprograms.
Fabiana Heredia +19 more
doaj +1 more source
Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death [PDF]
, 2006 Histolysis refers to a widespread disintegration of tissues that is morphologically distinct from apoptosis and often associated with the stimulation of autophagy. Here, we establish that a component of the apoptosome, and pivotal regulator of apoptosis,
Abrams, John M. +11 more
core +1 more source