Results 31 to 40 of about 17,129 (220)
Bab2 Functions as an Ecdysone-Responsive Transcriptional Repressor during Drosophila Development
Cell Reports, 2020 Summary: Drosophila development is governed by distinct ecdysone steroid pulses that initiate spatially and temporally defined gene expression programs. The translation of these signals into tissue-specific responses is crucial for metamorphosis, but the
Jianli Duan +7 more
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Increased insulin/insulin growth factor signaling advances the onset of metamorphosis in Drosophila. [PDF]
PLoS ONE, 2009 Mechanisms by which attainment of specific body sizes trigger developmental transitions to adulthood (e.g. puberty or metamorphosis) are incompletely understood.
Magdalena A Walkiewicz, Michael Stern
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Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death [PDF]
, 2006 Histolysis refers to a widespread disintegration of tissues that is morphologically distinct from apoptosis and often associated with the stimulation of autophagy. Here, we establish that a component of the apoptosome, and pivotal regulator of apoptosis,
Abrams, John M. +11 more
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Mechanisms regulating nutrition-dependent developmental plasticity through organ-specific effects in insects [PDF]
, 2013 Nutrition, via the insulin/insulin-like growth factor (IIS)/Target of Rapamycin (TOR) signaling pathway, can provide a strong molding force for determining animal size and shape.
Koyama, Takashi +2 more
core +2 more sources
PLoS ONE, 2023 Ecdysteroids control ovary growth and egg production through a complex gene hierarchy. In the female Rhodnius prolixus, a blood-gorging triatomine and the vector of Chagas disease, we have identified the ecdysone response genes in the ovary using ...
Samiha Benrabaa +2 more
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Steroid Hormone Signaling Is Essential to Regulate Innate Immune Cells and Fight Bacterial Infection in Drosophila [PDF]
, 2013 Coupling immunity and development is essential to ensure survival despite changing internal conditions in the organism. Drosophila metamorphosis represents a striking example of drastic and systemic physiological changes that need to be integrated with ...
Brandão, Ana S. +6 more
core +2 more sources
Nature Communications, 2021 Pupariation in Drosophila is triggered by the steroid-hormone ecdysone and requires coordination between associated behavioral and body-reshaping motor subprograms.
Fabiana Heredia +19 more
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Juvenile hormone regulates body size and perturbs insulin signaling in Drosophila [PDF]
, 2014 The role of juvenile hormone (JH) in regulating the timing and nature of insect molts is well-established. Increasing evidence suggests that JH is also involved in regulating final insect size.
Gokhale, R. H. +8 more
core +1 more source
Nature Communications, 2017 InDrosophila, ecdysone-regulated genes are bound by a heterodimer of ecdysone receptor (EcR) and Ultraspiracle. Here, the authors provide evidence of a non-canonical complex containing EcR and the nucleosome remodeller dMi-2 that limits transcription of ...
Judith Kreher +10 more
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Deep sequencing of the prothoracic gland transcriptome reveals new players in insect ecdysteroidogenesis. [PDF]
PLoS ONE, 2017 Ecdysteroids are steroid hormones that induce molting and determine developmental timing in arthropods. In insect larva, the prothoracic gland (PG) is a major organ for ecdysone synthesis and release.
Takayoshi Nakaoka +8 more
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