Pseudomonas aeruginosa and Candida spp. are biofilm-forming pathogens commonly found colonizing medical devices, being mainly associated with pneumonia and bloodstream infections.
Luciana Fernandes +3 more
doaj +1 more source
Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and Pathogenesis. [PDF]
Calcineurin signaling plays diverse roles in fungi in regulating stress responses, morphogenesis and pathogenesis. Although calcineurin signaling is conserved among fungi, recent studies indicate important divergences in calcineurin-dependent cellular ...
Juvvadi, P.R. +2 more
core +1 more source
Efficacy of caspofungin dose escalation against Candida albicans and Candida glabrata clinical isolates [PDF]
Munkánk során meghatároztuk a caspofungin által kifejtett ölési rátát RPMI-1640-ben, valamint 50% humán szérummal kiegészített tápközegben C. albicans és C. glabrata klinikai izolátumok ellen.
Domán, Marianna
core
The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K +11 more
core +3 more sources
BJU International, Volume 136, Issue 3, Page 408-411, September 2025.
Anne Sofie Frøkiær Mathiasen +3 more
wiley +1 more source
Rapid emergence of FKS mutations in Candida glabrata isolates in a peritoneal candidiasis
We report a rapid acquisition of echinocandin resistance after 12 days of micafungin treatment, without prior exposure, in a patient with peritoneal candidiasis due to C. glabrata. Isolates recovered before and after treatment were compared by multilocus
Milène Sasso +2 more
doaj +1 more source
Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis [PDF]
The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds.
Ana C. A. de Paula e Silva +8 more
core +1 more source
Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata. [PDF]
The echinocandins are relatively new antifungal drugs that represent, together with the older azoles, the recommended and/or preferred agents to treat candidaemia and other forms of invasive candidiasis in human patients.
De Carolis, E. +6 more
core +2 more sources
Echinocandin Resistance in Two Candida haemulonii Isolates from Pediatric Patients [PDF]
We report 3 cases of patients with Candida haemulonii isolates that were obtained from hemocultures. in 2 of the 3 cases, isolates exhibited resistance to echinocandins and fluconazole.
Azevedo Melo, Analy Salles de +4 more
core +1 more source
Drug Resistance in Eukaryotic Microorganisms [PDF]
Eukaryotic microbial pathogens are major contributors to illness and death globally. Although much of their impact can be controlled by drug therapy as with prokaryotic microorganisms, the emergence of drug resistance has threatened these treatment ...
A Abdolrasouli +193 more
core +4 more sources

