Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection [PDF]
This work was supported by the National Institutes of Health (R01AI080275 and R21AI22352), the NIH Fogarty International Center (R25TW009345), the University of Minnesota Center for Translational Science Institute (UL1TR000114), Wellcome Trust (086827 ...
Gow, Neil A R +5 more
core +1 more source
Emerging Frontiers in Clinical Mycology: Innovations, Insights, and Impacts
ABSTRACT The Mycoses Study Group Education and Research Consortium (MSGERC)—a group comprising clinicians, researchers, patients, and industry partners—meets every 2 years to review the most significant challenges facing the clinical mycology community and plan research, education, and advocacy strategies to prevent fungal infections and improve ...
A. Apostolopoulou +7 more
wiley +1 more source
Can Intravenous Antifungal therapy be safely used in the Outpatient Parenteral Antimicrobial Therapy (OPAT) setting? [PDF]
Outpatient parenteral antimicrobial therapy (OPAT) is an established treatment option for patients with a variety of infections who require a period of intravenous therapy, are clinically stable, and do not require continuous monitoring.
Kenny, Claire +2 more
core +2 more sources
ABSTRACT Background Invasive fungal infections (IFI) are a prominent cause of morbidity and mortality among patients with haematological malignancies (HMs). Diagnostic work‐up excluding IFI is mandatory in case of persistent fever while antifungal treatment (AFT) is started.
Criscuolo Marianna +29 more
wiley +1 more source
A Cross‐Sectional Study to Determine Candida spp. Carriage in Libyan Patients With Type 2 Diabetes
The risk for Candida infections in patients with diabetes mellitus (DM) is three times higher than in the general population. Despite a DM prevalence of 15.8% reported in Libya (2024), the laboratory identification and susceptibility testing of fungal infections in patients with DM are not routinely performed.
Mustafa H. M. Esmaio +3 more
wiley +1 more source
Histone deacetylase inhibition as an alternative strategy against invasive aspergillosis. [PDF]
Invasive aspergillosis (IA) is a life-threatening infection due to Aspergillus fumigatus and other Aspergillus spp. Drugs targeting the fungal cell membrane (triazoles, amphotericin B) or cell wall (echinocandins) are currently the sole therapeutic ...
Juvvadi, P.R. +2 more
core +2 more sources
Asymptomatic Candiduria due to Candida inconspicua in a Patient With Hematologic Malignancy
Candida inconspicua is an uncommon opportunistic yeast, increasingly reported in immunocompromised patients. We describe a case of asymptomatic Candiduria caused by C. inconspicua in a 43‐year‐old woman with Philadelphia chromosome‐positive B‐cell acute lymphoblastic leukemia undergoing chemotherapy.
Andrés Soto +12 more
wiley +1 more source
Portrait of matrix gene expression in Candida glabrata biofilms with stress induced by different drugs [PDF]
(1) Background: Candida glabrata is one of the most significant Candida species associated with severe cases of candidiasis. Biofilm formation is an important feature, closely associated with antifungal resistance, involving alterations of gene ...
Henriques, Mariana, Rodrigues, Célia F.
core +2 more sources
Abstract The qualified presumption of safety (QPS) process was developed to provide a harmonised safety assessment approach to support EFSA Scientific Panels and Units. The QPS approach assesses the taxonomic identity, body of relevant knowledge and safety of microorganisms intentionally added to the food and feed chain.
EFSA Panel on Biological Hazards (BIOHAZ) +28 more
wiley +1 more source
Candida infections, causes, targets and resistance mechanisms. Traditional and alternative antifungal agents [PDF]
The genus Candida includes about 200 different species, but only a few species are human opportunistic pathogens and cause infections when the host becomes debilitated or immunocompromised. Candida infections can be superficial or invasive.
Leonardi, Darío +1 more
core +3 more sources

