Results 81 to 90 of about 16,526 (218)

New cell wall-affecting antifungal antibiotics [PDF]

open access: yes, 2013
Capítulo 9.Fungi have emerged worldwide as increasingly frequent causes of healthcare-associated infections. Invasive fungal infections can be life-threatening.
Cortés, Juan Carlos G.   +2 more
core   +2 more sources

Integrated Genomic and Phenotypic Analyses Reveal Convergent Resistance Patterns in Clinical Candida tropicalis Isolates

open access: yesMycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background The incidence of Candida tropicalis isolation is increasing in hospital settings. High azole resistance and mortality rates make it a pathogen that requires further analysis. Methods Fourteen azole resistant Candida glabrata clinical isolates were collected from a Lebanese hospital and analysed through whole genome sequencing for ...
Christy Chedraoui   +9 more
wiley   +1 more source

Investigating the Chemical, Antifungal, and Cytotoxic Properties of Cochlospermum vitifolium Leaves and Stem Bark Extracts

open access: yesChemistry &Biodiversity, Volume 23, Issue 4, April 2026.
This figure contains images created by Freepik from Flaticon. ABSTRACT Comprehensive analysis of the chemical properties and bioactivities of plant extracts is essential for identifying compounds with therapeutic potential. This study analyzed hydroethanolic extracts from the leaves and stem bark of Cochlospermum vitifolium, investigating their ...
Francisco A. S. D. Pinheiro   +9 more
wiley   +1 more source

Breakthrough Bloodstream Infections Caused by Echinocandin-Resistant Candida tropicalis: An Emerging Threat to Immunocompromised Patients with Hematological Malignancies

open access: yesJournal of Fungi, 2020
Background. Candida tropicalis is a virulent fungal pathogen for which echinocandins are the primary therapy. Emergence of resistance to echinocandins of C. tropicalis carries potentially ominous therapeutic implications. Methods.
Maroun M. Sfeir   +8 more
doaj   +1 more source

Acute Invasive Pulmonary Aspergillosis With CNS Dissemination in an Immunocompetent Individual: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Invasive pulmonary aspergillosis can occur in patients without classical immunosuppression, particularly those with COPD and corticosteroid exposure. Early recognition, prompt antifungal therapy, and vigilance for neurological symptoms are essential to prevent central nervous system dissemination, which carries high mortality and significant ...
Barbare Khatiashvili   +8 more
wiley   +1 more source

Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi [PDF]

open access: yes, 2015
Genomics has revolutionized the research on fungal secondary metabolite (SM) biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the biosynthesis of a specific SM compound, the important first step is often to find the genes that
Cacho, Ralph A.   +2 more
core   +1 more source

Visible Photosensitizing Disinfectant Spray for Combating Multidrug‐Resistant Candidozyma Auris in Healthcare Settings

open access: yesExploration, Volume 6, Issue 2, April 2026.
We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu   +16 more
wiley   +1 more source

Susceptibility of Candida glabrata biofilms to echinocandins: alterations in the matrix composition [PDF]

open access: yes, 2018
Candidiases are the most recurrent fungal infections, especially among immunosuppressed patients. Although Candida albicans is still the most widespread isolated species, non-Candida albicans Candida species have been increasing.
Arendrup MC   +9 more
core   +1 more source

[Echinocandins].

open access: yesRevista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2012
The echinocandins, caspofugin, micafungin, and anidulafungin, are lipopeptides that inhibit fungal growth by binding to β - (1.3) d glucan synthase. This enzyme is responsible for the formation of the peptidoglycan cell wall, and it is essential in fungi such as Candida spp, but less important in the case of Aspergillus and Fusarium species.
Jorge A, Cortés L, July A, Russi N
openaire   +1 more source

The Influence of COVID‐19 on the Composition and Drug Resistance of Pleural Effusion in Shandong Province

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Our results show that the COVID‐19 pandemic has a significant impact on the detection of pathogens and drug resistance in pleural effusion in Shandong Province. ABSTRACT To analyze the composition and drug resistance changes of pleural effusion in Shandong region from 2017 to 2024, and to provide a basis for clinical empirical treatment and future ...
Wenwen Yu   +60 more
wiley   +1 more source

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