Results 71 to 80 of about 16,526 (218)

Caspofungin Induced Cell Wall Changes of Candida Species Influences Macrophage Interactions

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Candida species are known to differ in their ability to cause infection and have been shown to display varied susceptibilities to antifungal drugs. Treatment with the echinocandin, caspofungin, leads to compensatory alterations in the fungal cell wall ...
Louise A. Walker, Carol A. Munro
doaj   +1 more source

Clumping Morphology Influences Virulence Uncoupled from Echinocandin Resistance in Candida glabrata

open access: yesMicrobiology Spectrum, 2022
Here, we report two paired sets of an index wild-type Candida glabrata bloodstream isolate and subsequent echinocandin-resistant FKS mutant. One paired set exhibited a higher proportion of clumping cells and was more virulent in the invertebrate host ...
Chenlin Hu   +4 more
doaj   +1 more source

The seizure of illicit assets: patterns of civil forfeiture in Canada and Ireland [PDF]

open access: yes, 2013
No description ...
Gallant, M Michelle, King, Colin
core   +1 more source

Host Transcriptomics and Culture‐Independent Testing for the Management of Febrile Neutropenia: Data From an Observational Study Conducted in a Bone Marrow Transplant Unit

open access: yesEuropean Journal of Haematology, Volume 116, Issue 5, Page 625-634, May 2026.
ABSTRACT Background Managing febrile neutropenia is challenging due to the limited sensitivity of blood culture (BC) and the lack of tools differentiating infectious from non‐infectious fever. T2 magnetic resonance (T2MR) is a culture‐independent system detecting bacteria (T2Bacteria) and yeasts (T2Candida); SeptiCyte RAPID is a host response assay ...
Anna Maria Peri   +6 more
wiley   +1 more source

Comparison of echinocandin antifungals

open access: yesTherapeutics and Clinical Risk Management, 2007
The incidence of invasive fungal infections, especially those due to Aspergillus spp. and Candida spp., continues to increase. Despite advances in medical practice, the associated mortality from these infections continues to be substantial. The echinocandin antifungals provide clinicians with another treatment option for serious fungal infections ...
Gregory, Eschenauer   +2 more
openaire   +3 more sources

Candida Drug Resistance in Patients With Diabetic Foot Ulcers: A Systematic Review and Meta‐Analysis

open access: yesInternational Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Diabetic foot ulcers (DFUs) are one of the most serious and common complications that, if not treated properly, can lead to potential damage and even amputation. The aim of this systematic review and meta‐analysis was to assess the drug‐resistant Candida species in DFU.
Mohammad Hossein Ekvan   +7 more
wiley   +1 more source

Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance In Vitro and In Vivo

open access: yesmBio, 2022
Antifungal drug resistance and tolerance pose a serious threat to global public health. In the human fungal pathogen, Candida auris, resistance to triazole, polyene, and echinocandin antifungals is rising, resulting in multidrug resistant isolates. Here,
Laura S. Burrack   +4 more
doaj   +1 more source

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation [PDF]

open access: yes, 2014
Funding: JW and NARG thank the Wellcome Trust (080088, 086827, 075470), The Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology (097377) and the European Union ALLFUN (FP7/2007 2013, HEALTH-2010-260338) for funding. MGN was supported
Biedermann, Tilo   +12 more
core   +4 more sources

Invasive Fungal Infections After Intestine Transplantation: Epidemiology and Outcomes

open access: yesMycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background Invasive fungal infections (IFIs) represent a major complication after intestine transplantation, with reported incidence rates between 40% and 49%. These infections are associated with high morbidity and allograft loss. This study evaluates the impact of post‐transplant IFIs on graft outcomes in intestine transplant recipients ...
Mayyadah H. Alabdely   +4 more
wiley   +1 more source

Genomic and Molecular Identification of Genes Contributing to the Caspofungin Paradoxical Effect in Aspergillus fumigatus

open access: yesMicrobiology Spectrum, 2022
Aspergillus fumigatus is a deadly opportunistic fungal pathogen responsible for ~100,000 annual deaths. Azoles are the first line antifungal agent used against A.
Shu Zhao   +7 more
doaj   +1 more source

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