Results 71 to 80 of about 13,385 (164)
New approaches to the detection of echinocandin resistance in Candida glabrata in clinical diagnostic laboratories [PDF]
Candidaemia is widely reported as the fourth most common form of bloodstream infection worldwide. Reports of cases of candidaemia whilst patients are in receipt of antifungal therapy are increasing, and this is especially relevant as prescribing ...
Fraser, Mark Andrew
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浙江大学学报. 农业与生命科学版, 2017 Echinocandins are the first class of antifungals to target fungal cell wall. Two antifungals, including micafungin and anidulafungin, have been widely used in clinic.
FENG Guodong +6 more
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Practices of Antifungal Prophylaxis Among Italian Pediatric Oncology–Hematology Centers
eJHaem, Volume 7, Issue 4, August 2026.ABSTRACT Background IFD is a significant cause of illness and death among pediatric patients undergoing chemotherapy or HSCT. Application of AFP in children varies widely and is frequently off‐label. This survey aims to describe real‐world AFP practices across centers within AIEOP and provide an estimate of IFD incidence.
Martina Colli +23 more
wiley +1 more source
Fluconazole versus an echinocandin for Candida glabrata fungaemia: a retrospective cohort study
, 2014 Objectives: We studied whether fluconazole or echinocandin treatment of Candida glabrata fungaemia results in superior outcomes. Methods: A multicentre, retrospective study was performed with 224 adult patients who received >= 5 days of therapy with ...
Eschenauer, Gregory A.;Carver, Peggy L.;Lin, Shu-Wen;Klinker, Kenneth P.;Chen, Yee-Chun;Potoski, Brian A.;Shields, Ryan K.;Clancy, Cornelius J.;Nguyen, Minh-Hong;Lam, Simon W. +1 more
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MicrobiologyOpen, Volume 15, Issue 4, August 2026.This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino +10 more
wiley +1 more source
Echinocandin termelő törzs molekuláris genetikai törzsfejlesztése
, 2018 A dolgozatban bemutatásra kerül egy ipari és orvosi jelentőségű fonalas gomba, és annak iparilag releváns megközelítése. Továbbá ismertetésre kerül számos ipari technológia, mely segítségével a fonalas gomba hatóanyag termelése optimalizálható ...
Bodnár, Veronika
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Cryptic Production of trans -3-Hydroxyproline in Echinocandin B Biosynthesis
, 2018 Echinocandins are antifungal nonribosomal hexapeptides produced by fungi. Two of the amino acids are hydroxy- l -prolines: trans -4-hydroxy- l -proline and, in most echinocandin ...
Stefanie Houwaart +5 more
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Frontiers in Microbiology, 2019 A series of 4-(arylmethylene)-3-isochromanones have been prepared with base-catalyzed Knoevenagel condensation starting from 3-isochromanone and aromatic aldehydes.
Rodrigo Berzaghi +6 more
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Treatment of Invasive Candidiasis: A Narrative Review
Journal of Fungi, 2018 Invasive candidiasis occurs frequently in hospitalized patients, and is associated with high mortality rates due to delays in recognition and initiation of appropriate antifungals.
Ronen Ben-Ami
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Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata
Journal of Fungi, 2018 Candida glabrata has thoroughly adapted to successfully colonize human mucosal membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all the medically relevant Candida species, C.
Kelley R. Healey, David S. Perlin
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