Results 71 to 80 of about 12,523 (206)

Treatment of invasive candidiasis with echinocandins [PDF]

Mycoses, 2009
SummaryBlood stream infections by Candida spp. represent the majority of invasive fungal infections in intensive care patients. The high crude mortality of invasive candidiasis remained essentially unchanged during the last two decades despite new treatment options that became available.
Andreas, Glöckner, Angela, Steinbach, Jörg Janne, Vehreschild, Oliver A, Cornely   +3 more
openaire   +2 more sources

Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris

, 2018
Candida auris has simultaneously emerged on five continents as a fungal pathogen causing nosocomial outbreaks. The challenges in the treatment of C.
David S. Perlin, Steven Park, Lee, Annie, Anuradha Chowdhary, Chowdhary, Anuradha, Zhao, Yanan, Indira Berrio, Kordalewska, Milena, Park, Steven, Perlin, David S., Annie Lee, Milena Kordalewska, Berrio, Indira, Yanan Zhao   +13 more
core   +1 more source

Breakthrough Bloodstream Infections Caused by Echinocandin-Resistant Candida tropicalis: An Emerging Threat to Immunocompromised Patients with Hematological Malignancies

Journal of Fungi, 2020
Background. Candida tropicalis is a virulent fungal pathogen for which echinocandins are the primary therapy. Emergence of resistance to echinocandins of C. tropicalis carries potentially ominous therapeutic implications. Methods.
Maroun M. Sfeir, Cristina Jiménez-Ortigosa, Maria N. Gamaletsou, Audrey N. Schuetz, Rosemary Soave, Koen Van Besien, Catherine B. Small, David S. Perlin, Thomas J. Walsh   +8 more
doaj   +1 more source

Candida glabrata Isolated From Tubo‐Ovarian Abscess Cultures in Two Immunocompetent Patients

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Persistent 7.3 × 5.8 cm TOA unresponsive to 4 weeks of antibiotic treatment and percutaneous drainage, growing Candida glabrata on cultures. ABSTRACT In this clinical case report, we present two immunocompetent patients with tubo‐ovarian abscesses (TOAs) that were positive for Candida glabrata.
Marlee Hirsch, Rosalie DePaola, Jordan Eisenberg, Amir Shay, Tyler M. Moore, Adi Katz, Richard A. Stein   +6 more
wiley   +1 more source

Fluconazole versus an echinocandin for Candida glabrata fungaemia: a retrospective cohort study

, 2014
Objectives: We studied whether fluconazole or echinocandin treatment of Candida glabrata fungaemia results in superior outcomes. Methods: A multicentre, retrospective study was performed with 224 adult patients who received >= 5 days of therapy with ...
Eschenauer, Gregory A.;Carver, Peggy L.;Lin, Shu-Wen;Klinker, Kenneth P.;Chen, Yee-Chun;Potoski, Brian A.;Shields, Ryan K.;Clancy, Cornelius J.;Nguyen, Minh-Hong;Lam, Simon W., 林淑文 ;陳宜君   +1 more
core   +1 more source

Epidemiology of Echinocandin Resistance in Candida [PDF]

Current Fungal Infection Reports, 2014
Echinocandins are the newest antifungal agents approved for use in treating Candida infections in the US. They act by interfering with 1,3-β-D-glucan synthase and therefore disrupt cell wall production and lead to Candida cell death. There is no intrinsic resistance to echinocandins among Candida species, and isolates from historic collections archived
Nina T, Grossman, Tom M, Chiller, Shawn R, Lockhart   +2 more
openaire   +2 more sources

Synergistic activity of caspofungin and posaconazole against Candida (Candidozyma) auris biofilms based on phenotypic, transcriptomic, and in vivo insights

Microbiology Spectrum
Candida (Candidozyma) auris is an emerging multidrug-resistant fungal pathogen capable of establishing persistent skin colonization, contaminating the environment, and causing nosocomial outbreaks associated with high mortality rates.
Fruzsina Kovács, Andrea Harmath, Dávid Balázsi, Lajos Forgács, Ágota Ragyák, Noémi Balla, Zoltán Tóth, Aliz Bozó, Andrew M. Borman, László Majoros, Renátó Kovács, Ágnes Jakab   +11 more
doaj   +1 more source

Probiotic‐based strategies in vulvovaginal candidiasis management: A comprehensive review of mechanisms and future directions

Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.
This review focuses on vulvovaginal candidiasis (VVC), examining its epidemiology, the pathogenesis of Candida albicans, and its relationships with vaginal microbiota. It comprehensively reviews probiotic‐based management strategies and their mechanisms of action, and concludes by discussing current limitations, challenges and future research ...
Tong Chen, Yuwei Wu, Ya Chen, Ying Li, Hui Zhao, Lei Wu, He Gao, Tong Jiang, Xiaohong Wang, Moutong Chen, Jumei Zhang, Xinqiang Xie, Tingting Liang, Qingping Wu   +13 more
wiley   +1 more source

[Echinocandins].

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2012
The echinocandins, caspofugin, micafungin, and anidulafungin, are lipopeptides that inhibit fungal growth by binding to β - (1.3) d glucan synthase. This enzyme is responsible for the formation of the peptidoglycan cell wall, and it is essential in fungi such as Candida spp, but less important in the case of Aspergillus and Fusarium species.
Jorge A, Cortés L, July A, Russi N
openaire   +1 more source

Antifungal Echinocandin

, 2019
Infeksi fungal invasif (IFI) masih menjadi penyebab utama morbiditas dan mortalitas pasien immunocompromised. Pilihan antifungal yang tersedia untuk IFI terbatas pada polyene, triazole, dan echinocandin.
Lukito, J. I. (Johan)
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