Results 111 to 120 of about 13,766 (257)
Mycology, 2018 The purpose of this study was to determine whether fungicidal versus fungistatic pharmacotherapy of invasive candidiasis/candidemia yields superior outcomes. Data sources included MEDLINE (1966–June 2017), EMBASE (1980–June 2017), PubMed (1966–June 2017),
Anand Kumar +5 more
doaj +1 more source
New cell wall-affecting antifungal antibiotics [PDF]
, 2013 Capítulo 9.Fungi have emerged worldwide as increasingly frequent causes of healthcare-associated infections. Invasive fungal infections can be life-threatening.
Cortés, Juan Carlos G. +2 more
core +2 more sources
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi [PDF]
, 2015 Genomics has revolutionized the research on fungal secondary metabolite (SM) biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the biosynthesis of a specific SM compound, the important first step is often to find the genes that
Cacho, Ralph A. +2 more
core +1 more source
Therapeutic Effects of Water-Soluble Echinocandin Compounds on Pneumocystis Pneumonia in Mice [PDF]
, 1998 Takahisa Furuta +5 more
openalex +1 more source
Microbiology SpectrumThe minimum inhibitory concentration (MIC) of echinocandins against Aspergillus spp. does not represent the actual inhibition threshold of echinocandins.
Assaf Potruch +5 more
doaj +1 more source
Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]
, 2020 There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus +8 more
core +1 more source
The Effect of the Echinocandin Analogue Caspofungin on Cell Wall Glucan Synthesis byCryptococcus neoformans [PDF]
, 2000 Marta Feldmesser +3 more
openalex +1 more source
3 Biotech, 2019 Anidulafungin, a new class of antifungal agent used for the treatment of chronic fungal infections, is derived from Echinocandin B nucleus, an intermediate metabolite of Echinocandin B produced by Aspergillus nidulans. The enzyme acylase plays a key role in the bioconversion of Echinocandin B to Echinocandin B nucleus.
J. Savitha +5 more
openaire +3 more sources
mSphereAspergillus fumigatus is a major invasive mold pathogen and the most frequent etiologic agent of invasive aspergillosis. The currently available treatments for invasive aspergillosis are limited in both number and efficacy.
Harrison I. Thorn +6 more
doaj +1 more source
In vitro antifungal activity of FK463, a new water-soluble echinocandin-like lipopeptide [PDF]
, 2000 Hiroshige Mikamo +2 more
openalex +1 more source